Protein Arginine Methyltransferase 2 (PRMT2) (N-Term) Peptide
PRMT2
适用: 人
宿主: 合成
BP, WB, ChIP
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- 抗原 See all PRMT2 products
- PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-PRMT2 antibody (Catalog #: ARP40195_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))
- 别名
- PRMT2 Peptide, DKFZp459N1919 Peptide, HRMT1L1 Peptide, Hrmt1l1 Peptide, AI504737 Peptide, protein arginine methyltransferase 2 Peptide, protein arginine methyltransferase 2 L homeolog Peptide, protein arginine N-methyltransferase 2 Peptide, PRMT2 Peptide, Prmt2 Peptide, prmt2.L Peptide
- 背景
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The protein arginine methyltransferases (PRMTs) include a family of proteins with related putative methyltransferase domains that modify chromatin and regulate cellular transcription. PRMT2 inhibits NF-kappaB-dependent transcription and promotes apoptosis and it exerts this effect by blocking nuclear export of IkappaB-alpha through a leptomycin-sensitive pathway, increasing nuclear IkappaB-alpha and decreasing NF-kappaB DNA binding. PRMT2 also rendered cells susceptible to apoptosis by cytokines or cytotoxic drugs, likely due to its effects on NF-kappaB.
Alias Symbols: HRMT1L1, MGC111373
Protein Interaction Partner: ESR1,ESR2,NCOA1,NCOA6,PGR,PPARG,PRMT2,RARA,RXRA,THRB,BAT2,CPSF7,DMRTB1,ESR1,ESR2,HNRNPUL1,NCOA1,NCOA6,PGR,PRMT2,RB1,RXRA,THRB,BAT2,CPSF7,DMRTB1,ESR1,HNRNPUL1
Protein Size: 433 - 分子量
- 49 kDa
- 基因ID
- 3275
- NCBI登录号
- NM_001535, NP_001526
- UniProt
- P55345
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