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Protection of Telomeres 1 (POT1) (Middle Region) Peptide

POT1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN981996
发货至: 中国
  • 抗原 See all POT1 products
    POT1 (Protection of Telomeres 1 (POT1))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 4
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    CPKCHLLQEV PHEGDLDIIF QDGATKTPDV KLQNTSLYDS KIWTTKNQKG
    产品特性
    This is a synthetic peptide designed for use in combination with anti-POT1 Antibody(ARP58318_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    POT1 (Protection of Telomeres 1 (POT1))
    别名
    HPOT1 Peptide, POT1 Peptide, DKFZp469P1825 Peptide, pot1 Peptide, 1500031H18Rik Peptide, AI851169 Peptide, Pot1 Peptide, Pot1a Peptide, protection of telomeres 1 Peptide, protection of telomeres 1 L homeolog Peptide, protection of telomeres 1A Peptide, POT1 Peptide, pot1.L Peptide, Pot1a Peptide, Pot1 Peptide
    背景
    This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

    Alias Symbols: DKFZP586D211, hPot1, HPOT1

    Protein Interaction Partner: ACD,ACD,TERF1,TNKS,ACD,TERF1,TINF2,TNKS

    Protein Size: 503
    分子量
    57 kDa
    基因ID
    25913
    NCBI登录号
    NM_001042594, NP_001036059
    UniProt
    Q9NUX5
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