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Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (Middle Region) Peptide

P2RX7 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN981273
发货至: 中国
  • 抗原 See all P2RX7 products
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 10
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-P2RX7 antibody (Catalog #: ARP35112_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
    别名
    p2xr7 Peptide, P2RX7 Peptide, P2X7 Peptide, AI467586 Peptide, P2X(7) Peptide, P2X7R Peptide, p2x7 Peptide, purinergic receptor P2X 7 Peptide, purinergic receptor P2X, ligand-gated ion channel, 7 Peptide, P2X purinoceptor 7 Peptide, P2RX7 Peptide, p2rx7 Peptide, LOC100458463 Peptide, P2rx7 Peptide
    背景
    The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: MGC20089, P2X7

    Protein Interaction Partner: ACTB,EMP3,PANX1,SVIL

    Protein Size: 595
    分子量
    68 kDa
    基因ID
    5027
    NCBI登录号
    NM_002562, NP_002553
    UniProt
    Q99572
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