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N-Acetylneuraminic Acid Synthase (NANS) (C-Term) Peptide

NANS 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN980481
发货至: 中国
  • 抗原 See all NANS products
    NANS (N-Acetylneuraminic Acid Synthase (NANS))
    蛋白结构域
    C-Term
    宿主
    资源
    • 2
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    DMLTVKVGEP KGYPPEDIFN LVGKKVLVTV EEDDTIMEEL VDNHGKKIKS
    产品特性
    This is a synthetic peptide designed for use in combination with anti-NANS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    NANS (N-Acetylneuraminic Acid Synthase (NANS))
    别名
    MGC84329 Peptide, SAS Peptide, N-acetylneuraminate synthase L homeolog Peptide, N-acetylneuraminate synthase Peptide, nans.L Peptide, NANS Peptide, Nans Peptide
    背景
    This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.

    Alias Symbols: SAS

    Protein Interaction Partner: DDA1,UBC

    Protein Size: 359
    分子量
    40 kDa
    基因ID
    54187
    NCBI登录号
    NM_018946, NP_061819
    UniProt
    Q9NR45
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