Mediator Complex Subunit 7 (MED7) (C-Term) Peptide
MED7
适用: 人
宿主: 合成
BP, WB, ChIP
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- 抗原 See all MED7 products
- MED7 (Mediator Complex Subunit 7 (MED7))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- 序列
- LASLPDDLPH SEAGMRVKTE PMDADDSNNC TGQNEHQREN SGHRRDQIIE
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-MED7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- MED7 (Mediator Complex Subunit 7 (MED7))
- 背景
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CRSP33, CRSP9, MGC12284, ARC34
Protein Interaction Partner: HGS,MED8,MED9,BARHL1,CDK8,CTDP1,ESR1,ESR2,FXR2,HGS,HNF4A,IKBKG,LZTR1,MED1,MED10,MED14,MED15,MED19,MED22,MED25,MED26,MED28,MED29,MED31,MED9,PARP1,PCBD2,PML,RBFOX2,RELA,RHOXF2,SREBF1,TRIM15,TRIM29,UBAC1,VDR,ZSCAN1
Protein Size: 233 - 分子量
- 27 kDa
- 基因ID
- 9443
- NCBI登录号
- NM_004270, NP_004261
- UniProt
- O43513
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