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Gap Junction Protein, alpha 1, 43kDa (GJA1) (Middle Region) Peptide

GJA1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN977414
发货至: 中国
  • 抗原 See all Connexin 43/GJA1 (GJA1) products
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    蛋白结构域
    Middle Region
    宿主
    资源
    • 10
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-GJA1 antibody (Catalog #: ARP36597_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))
    别名
    AVSD3 Peptide, CX43 Peptide, DFNB38 Peptide, GJAL Peptide, HLHS1 Peptide, HSS Peptide, ODDD Peptide, Cx43 Peptide, AU042049 Peptide, AW546267 Peptide, Cnx43 Peptide, Cx43alpha1 Peptide, Gja-1 Peptide, Npm1 Peptide, connexin43 Peptide, cx43a1 Peptide, gja1 Peptide, zfCx43.3 Peptide, connexin 43 Peptide, gja1-A Peptide, cx43 Peptide, gjal Peptide, oddd Peptide, dfnb38 Peptide, gap junction protein alpha 1 Peptide, gap junction protein, alpha 1 Peptide, connexin 43 Peptide, gap junction protein alpha 1 L homeolog Peptide, CONNEXIN 43 protein Peptide, GJA1 Peptide, Gja1 Peptide, cx43 Peptide, gja1.L Peptide, gja1 Peptide, CONNEXIN 43 Peptide
    背景
    Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5. This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia and heart malformations. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: CX43, DFNB38, GJAL, ODDD, HSS, AVSD3, HLHS1

    Protein Interaction Partner: SRC,CAV1,CSK,CSNK1D,GJA3,GJA5,MAPK1,MAPK3,MAPK7,NOV,PRKCA,PRKCB,PRKCE,PRKCG,S100A1,SGSM3,SRC,TJP1,CAV1,CSNK1D,GJA1,GJA3,GJA5,MAPK7,PRKCA,PRKCE,S100A1,TJP1

    Protein Size: 382
    分子量
    43 kDa
    基因ID
    2697
    NCBI登录号
    NM_000165, NP_000156
    UniProt
    P17302
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