Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC) (Middle Region) Peptide
GCLC
适用: 人
宿主: 合成
BP, IHC, WB
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- 抗原 See all GCLC products
- GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- 序列
- RISKSRYDSI DSYLSKCGEK YNDIDLTIDK EIYEQLLQEG IDHLLAQHVA
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-GCLC Antibody(ARP54577_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- GCLC (Glutamate-Cysteine Ligase, Catalytic Subunit (GCLC))
- 别名
- GCLC Peptide, gclc Peptide, MGC146287 Peptide, 2259 Peptide, CG2259 Peptide, DmGCLC Peptide, DmGCS Peptide, DmGCSh Peptide, Dmel\\CG2259 Peptide, GCL Peptide, GCLc Peptide, GCSh Peptide, Gcs Peptide, Gcsh Peptide, DDBDRAFT_0186120 Peptide, DDBDRAFT_0231403 Peptide, DDB_0186120 Peptide, DDB_0231403 Peptide, GCS Peptide, GLCL Peptide, GLCLC Peptide, D9Wsu168e Peptide, GLCL-H Peptide, Ggcs-hs Peptide, Glclc Peptide, cb1049 Peptide, fe36e11 Peptide, wu:fe36e11 Peptide, glutamate-cysteine ligase catalytic subunit Peptide, glutamate-cysteine ligase, catalytic subunit Peptide, Glutamate-cysteine ligase catalytic subunit Peptide, gamma glutamylcysteine synthetase Peptide, glutamate-cysteine ligase, catalytic subunit L homeolog Peptide, glutamate-cysteine ligase, catalytic subunit S homeolog Peptide, gamma-glutamylcysteine synthetase Peptide, GCLC Peptide, gclc Peptide, Gclc Peptide, LbGCS Peptide, gcsA Peptide, gclc.L Peptide, gclc.S Peptide, GSH1 Peptide
- 背景
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Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC is the catalytic subunit of 637 amino acids with a calculated molecular weight of 72.773 kDa. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia.
Alias Symbols: GCL, GCS, GLCL, GLCLC
Protein Size: 637 - 分子量
- 73 kDa
- 基因ID
- 2729
- NCBI登录号
- NM_001498, NP_001489
- UniProt
- P48506
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