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Complement Component C4b (C4b) (N-Term) Peptide

C4b 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN974249
发货至: 中国
  • 抗原 See all C4B (C4b) products
    C4B (C4b) (Complement Component C4b (C4b))
    蛋白结构域
    N-Term
    宿主
    资源
    • 1
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-C4B antibody (Catalog #: ARP41841_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    C4B (C4b) (Complement Component C4b (C4b))
    别名
    C4B1 Peptide, C4B12 Peptide, C4B2 Peptide, C4B3 Peptide, C4B5 Peptide, C4BD Peptide, C4B_2 Peptide, C4F Peptide, CH Peptide, CO4 Peptide, CPAMD3 Peptide, C4 Peptide, C4A2 Peptide, C4A3 Peptide, C4A4 Peptide, C4A6 Peptide, C4AD Peptide, C4S Peptide, CPAMD2 Peptide, RG Peptide, wu:fi14a03 Peptide, C4B Peptide, DKFZP469I0332 Peptide, Slp Peptide, Ss Peptide, C4-2 Peptide, C4l Peptide, complement C4B (Chido blood group) Peptide, complement C4A (Rodgers blood group) Peptide, complement component 4 Peptide, complement C4-B Peptide, complement component 4B (Chido blood group) Peptide, complement component 4A (Rodgers blood group) Peptide, C4B Peptide, C4A Peptide, c4 Peptide, LOC462577 Peptide, C4a Peptide, C4b Peptide
    背景
    C4B is the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: C4A, C4A13, C4A91, C4B1, C4B12, C4B2, C4B3, C4B5, C4F, CH, CO4, CPAMD3, MGC164979

    Protein Size: 1744
    分子量
    33 kDa
    基因ID
    432395
    NCBI登录号
    NM_001002029, NP_001002029
    UniProt
    Q6U2E9
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