Angiotensin II Receptor, Type 1 (AGTR1) (N-Term) Peptide
AGTR1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all Angiotensin II Type-1 Receptor (AGTR1) products
- Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-AGTR1 antibody (Catalog #: ARP42198_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))
- 别名
- AG2S Peptide, AGTR1A Peptide, AGTR1B Peptide, AT1 Peptide, AT1AR Peptide, AT1B Peptide, AT1BR Peptide, AT1R Peptide, AT2R1 Peptide, AT2R1A Peptide, AT2R1B Peptide, HAT1R Peptide, 1810074K20Rik Peptide, AI551199 Peptide, AT1a Peptide, Agtr-1a Peptide, Agtr1 Peptide, Angtr-1a Peptide, AT1A Peptide, XAT-1 Peptide, agtr1-A Peptide, agtr1.2 Peptide, AT1-R Peptide, at1 Peptide, AGTR1 Peptide, Agtr-1b Peptide, Angtr-1b Peptide, agtr1 Peptide, agtr1-a Peptide, agtr1-b Peptide, xAT Peptide, angiotensin II receptor type 1 Peptide, angiotensin II receptor, type 1a Peptide, angiotensin II receptor type 1 S homeolog Peptide, uncharacterized AGTR1 Peptide, angiotensin II receptor, type 1b Peptide, angiotensin II receptor type 1 L homeolog Peptide, AGTR1 Peptide, Agtr1a Peptide, agtr1.S Peptide, Agtr1 Peptide, Agtr1b Peptide, agtr1.L Peptide
- 背景
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Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. AGTR1 is the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. AGTR1 may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans.Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants.
Alias Symbols: AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R, AT1R
Protein Interaction Partner: ADRBK1,ADRBK2,AGT,AGTRAP,ARRB1,ARRB2,BDKRB2,DNAJC14,EGFR,GPRASP1,GRK5,HRAS,JAK2,NOS3,PLCG1,RAB5A,RAF1,THOP1,ADRBK1,AGTRAP,BDKRB2,GRK5,RAB5A,ZBTB16
Protein Size: 359 - 分子量
- 41 kDa
- 基因ID
- 185
- NCBI登录号
- NM_004835, NP_004826
- UniProt
- P30556
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