A synthetic peptide for use as a blocking control in assays to test for specificity of PI3 antibody, Alternative Names: PI3 control peptide, PI3 antibody Blocking Peptide, Anti-PI3 Blocking Peptide, Peptidase Inhibitor 3 Skin-Derived Blocking Peptide, Skalp Blocking Peptide, ESI Blocking Peptide, MGC13613 Blocking Peptide, SKALP Blocking Peptide, WAP3 Blocking Peptide, WFDC14 Blocking Peptide, PI3, PI-3, PI 3, PI-3 Blocking Peptide, PI 3 Blocking Peptide
PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.