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GRB2-Related Adaptor Protein (GRAP) (N-Term) Peptide

GRAP 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN2184413
发货至: 中国
  • 抗原 See all GRAP products
    GRAP (GRB2-Related Adaptor Protein (GRAP))
    蛋白结构域
    N-Term
    宿主
    资源
    • 5
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    SDELAFNKGD TLKILNMEDD QNWYKAELRG VEGFIPKNYI RVKPHPWYSG
    产品特性
    This is a synthetic peptide designed for use in combination with antiGRAP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at 20C. Avoid repeat freezethaw cycles.
  • 抗原
    GRAP (GRB2-Related Adaptor Protein (GRAP))
    别名
    8430435N19Rik Peptide, BB233594 Peptide, GRAP Peptide, grap Peptide, zgc:110202 Peptide, MGC109892 Peptide, si:dkeyp-9d4.1 Peptide, Grap Peptide, GRB2-related adaptor protein Peptide, GRB2-related adapter protein Peptide, GRB2-related adaptor protein a Peptide, GRB2-related adaptor protein b Peptide, GRAP Peptide, Grap Peptide, LOC489534 Peptide, grapa Peptide, grapb Peptide, LOC100727005 Peptide
    背景
    This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligandactivated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCRABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its Nterminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

    Alias Symbols: -

    Protein Size: 217
    分子量
    25 kDa
    基因ID
    10750
    NCBI登录号
    NM_006613, NP_006604
    UniProt
    Q13588
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