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Bone Morphogenetic Protein 10 (BMP10) (C-Term) Peptide

BMP10 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN2183892
发货至: 中国
  • 抗原 See all BMP10 products
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    蛋白结构域
    C-Term
    宿主
    资源
    • 4
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    GYEAYECRGV CNYPLAEHLT PTKHAIIQAL VHLKNSQKAS KACCVPTKLE
    产品特性
    This is a synthetic peptide designed for use in combination with anti-BMP10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    BMP10 (Bone Morphogenetic Protein 10 (BMP10))
    别名
    BMP10 Peptide, si:dkey-13n15.5 Peptide, Bmp10 Peptide, BMP9 Peptide, BMP-10 Peptide, bone morphogenetic protein 10 Peptide, BMP10 Peptide, bmp10 Peptide, LOC662386 Peptide, Bmp10 Peptide
    背景
    BMP10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. It acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.

    Alias Symbols: -

    Protein Size: 424
    分子量
    46 kDa
    基因ID
    27302
    NCBI登录号
    NM_014482, NP_055297
    UniProt
    O95393
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