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POMC 蛋白

(Proopiomelanocortin (POMC))
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used\; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].
POMC Protein (AA 205-267) (GST tag) POMC Protein (AA 205-267) (GST tag) POMC Protein (AA 205-267) (GST tag) (ABIN1315730)

POMC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA

POMC Protein (AA 27-267) (His tag) POMC Protein (AA 27-267) (His tag) POMC Protein (AA 27-267) (His tag) (ABIN7124601)

POMC 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

POMC Protein (AA 27-267) (His-IF2DI Tag) POMC Protein (AA 27-267) (His-IF2DI Tag) POMC Protein (AA 27-267) (His-IF2DI Tag) (ABIN7124600)

POMC 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA

POMC 蛋白 by Origin

Find POMC 蛋白 for a variety of species such as anti-Human POMC, anti-Rat POMC, anti-Acipenser transmontanus POMC. The species listed below are among those available. Click on a link to go to the corresponding products.

POMC 蛋白 by Source

Here you will find POMC 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

POMC 蛋白 by 蛋白类型

Here you can find POMC 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

POMC 蛋白 by 应用范围

Find POMC 蛋白 validated for a specific application such as ELISA, WB, SDS, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular POMC 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1315730
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124601
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124600
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315729
Quantity 25 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7405103
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7393751
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415977
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3011313
Quantity 100 μg
Datasheet Datasheet
Reactivity Guinea Pig
Source Yeast
Validations
Cat. No. ABIN1661110
Quantity 1 mg
Datasheet Datasheet
Reactivity Macaca nemestrina
Source Yeast
Validations
Cat. No. ABIN1666425
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1666424
Quantity 1 mg
Datasheet Datasheet
Reactivity Frog
Source Yeast
Validations
Cat. No. ABIN1663113
Quantity 1 mg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1667025
Quantity 1 mg
Datasheet Datasheet
Reactivity Bullfrog
Source Yeast
Validations
Cat. No. ABIN1660328
Quantity 1 mg
Datasheet Datasheet
Reactivity Pig
Source Yeast
Validations
Cat. No. ABIN1666423
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our POMC 蛋白

La Rosa, Uccella, Dainese, Marchet, Placidi, Vigetti, Capella: "Characterization of c-kit (CD117) expression in human normal pituitary cells and pituitary adenomas." in: Endocrine pathology, Vol. 19, Issue 2, pp. 104-11, (2008) (PubMed).

Aliases for POMC 蛋白

proopiomelanocortin a (pomca) 蛋白
pro-opiomelanocortin-alpha (Pomc) 蛋白
proopiomelanocortin (POMC) 蛋白
proopiomelanocortin (Pomc) 蛋白
ACTH 蛋白
alpha-MSH 蛋白
alphaMSH 蛋白
BE 蛋白
Beta-LPH 蛋白
beta-MSH 蛋白
Clip 蛋白
CLIP 蛋白
Gamma-LPH 蛋白
gamma-MSH 蛋白
LPH 蛋白
MSH 蛋白
Npp 蛋白
NPP 蛋白
POC 蛋白
pomc 蛋白
Pomc-1 蛋白
Pomc1 蛋白
Pomc2 蛋白
SI:bZ36D5.1 蛋白
si:bz36d5.2 蛋白
SI:bZ36D5.4 蛋白
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