anti-豚鼠 TANK 抗体 for Western Blotting

Recommended TANK Antibody (supplied by: Log in to see )

抗原
TRAF Family Member-Associated NFKB Activator (TANK) 抗体
  • C86182
  • E430026L09Rik
  • I-TRAF
  • ITRAF
  • TRAF2
  • TRAF family member-associated NFKB activator
  • TRAF family member-associated Nf-kappa B activator
  • TANK
  • Tank
抗原表位
N-Term
20
19
14
13
10
5
4
3
2
2
1
1
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 猪, 兔, 大鼠
120
47
43
10
6
5
5
4
3
3
2
2
1
宿主

114
3
2
1
1
克隆类型
多克隆
标记
This TANK antibody is un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
107
44
35
26
16
16
14
13
10
3
3
2
1
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产品编号 ABIN2780571
24,451.51 ¥
(含税, 含运费)
来自4A Biotech Co.,Ltd.(本地经销商)
获取报价
中国 北京 101111
No. 88 KeChuang 6th Street
Room 801-803
Beijing Economic Technological Development Area
4A Biotech Co.,Ltd.
Tel 400-7060-959
传真 +86 10 56315212-8813
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
2.9488602 ABIN2779542 WB Rabbit N-Term Log in to see Polyclonal
2.9488602 ABIN2779297 WB Rabbit N-Term Log in to see Polyclonal
1 ABIN1834091 WB Rabbit AA 48-97 Log in to see Polyclonal

General

抗原 TRAF Family Member-Associated NFKB Activator (TANK) 抗体
抗原表位 N-Term
(20), (19), (14), (13), (10), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1)
适用 牛, 犬, 豚鼠, 马, 人, 小鼠, 猪, 兔, 大鼠
(120), (47), (43), (10), (6), (5), (5), (4), (3), (3), (2), (2), (1)
宿主
(114), (3), (2), (1), (1)
克隆类型
多克隆
标记 This TANK antibody is un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunohistochemistry (IHC), Western Blotting (WB)
(107), (44), (35), (26), (16), (16), (14), (13), (10), (3), (3), (2), (1)
Pubmed 找到1个引用
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TANK抗体详情

TANK目标详情 使用细节 贮存及处理 ProductDetails: References for anti-TANK antibody (ABIN2780571) 图像
Blocking Peptide Blocking peptide for this product available: ABIN984763
序列 DKNIGEQLNK AYEAFRQACM DRDSAVKELQ QKTENYEQRI REQQEQLSLQ
预测反应 Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%
产品特性 This is a rabbit polyclonal antibody against TANK. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
免疫原 The immunogen is a synthetic peptide directed towards the N terminal region of human TANK

TANK目标详情

TANK抗体详情 使用细节 贮存及处理 ProductDetails: References for anti-TANK antibody (ABIN2780571) 图像 回页首
抗原
别名 TANK (TANK Antibody 摘要)
背景 The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, TANK can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation.The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: I-TRAF, TRAF2
Protein Interaction Partner: CEP63, TP53BP2, SRSF11, UBC, TBK1, BIRC3, BIRC2, INPP5K, ATP6V1H, RACGAP1, TANK, IKBKE, IKBKG, AIMP2, TRAF2, TRAF1, SDC4, PLK1, SMAD3, LAMC1, KPNA2, HLA-C, FBLN1, COPB1, BIK, APP, TRAF3, TAB2, MAP3K14, HERC2, CD40, CBLB, TICAM1, APBA3, MARCH5, ZC3H12A, MA
Protein Size: 425
分子量 48 kDa
基因ID 10010
NCBI登录号 NM_004180, NP_004171
UniProt Q92844
研究领域 Immunology, Innate Immunity
途径 p53 Pathway, TLR signaling, Activation of Innate immune Response

使用细节

TANK抗体详情 TANK目标详情 贮存及处理 ProductDetails: References for anti-TANK antibody (ABIN2780571) 图像 回页首
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 425 AA

限制 仅限研究用

贮存及处理

TANK抗体详情 TANK目标详情 使用细节 ProductDetails: References for anti-TANK antibody (ABIN2780571) 图像 回页首
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

ProductDetails: References for anti-TANK antibody (ABIN2780571)

TANK抗体详情 TANK目标详情 使用细节 贮存及处理 图像 回页首
背景

Gatot, Gioia, Chau, Patrascu, Warnier, Close, Chapelle, Muraille, Brown, Siebenlist, Piette, Dejardin, Chariot: "Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF." in: The Journal of biological chemistry, Vol. 282, Issue 43, pp. 31131-46, 2007

图像

TANK抗体详情 TANK目标详情 使用细节 贮存及处理 ProductDetails: References for anti-TANK antibody (ABIN2780571) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-TRAF Family Member-Associated NFKB Activator (TANK) (N-Term) antibody (ABIN2780571) WB Suggested Anti-TANK Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...