anti-小鼠 Stratifin 抗体 for Immunofluorescence (Paraffin-embedded Sections)

Recommended Stratifin Antibody (supplied by: Log in to see )

抗原
Stratifin (SFN) 抗体
  • YWHAS
  • Er
  • Mme1
  • Ywhas
  • stratifin
  • SFN
  • Sfn
适用
人, 小鼠, 大鼠
197
67
52
15
14
14
11
10
8
7
5
4
4
2
2
2
1
1
1
1
1
宿主

146
36
21
2
1
克隆类型
多克隆
标记
This Stratifin antibody is conjugated to Alexa Fluor 350
12
9
7
7
6
6
1
1
1
1
1
1
1
1
1
1
应用范围
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
176
81
71
50
43
21
21
18
12
4
3
3
2
1
1
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产品编号 ABIN1693816
产品在该地区无法提供。
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中国 北京 101111
No. 88 KeChuang 6th Street
Room 801-803
Beijing Economic Technological Development Area
4A Biotech Co.,Ltd.
Tel 400-7060-959
传真 +86 10 56315212-8813
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1695638 IF (p) Alexa Fluor 488 Rabbit IgG Log in to see Polyclonal
1 ABIN1697459 IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal
1 ABIN1699270 IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal
1 ABIN1702896 IF (p) Cy3 Rabbit IgG Log in to see Polyclonal
1 ABIN1704707 IF (p) Cy5 Rabbit IgG Log in to see Polyclonal
1 ABIN1706665 IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal
1 ABIN1708476 IF (p) Cy7 Rabbit IgG Log in to see Polyclonal
1 ABIN1710287 IF (p) FITC Rabbit IgG Log in to see Polyclonal
1 ABIN2809284 IF (p) Alexa Fluor 594 Rabbit IgG Log in to see Polyclonal
1 ABIN1714586 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN4995750 IF (p) Alexa Fluor 680 Rabbit IgG Log in to see Polyclonal
1 ABIN4995751 IF (p) Alexa Fluor 750 Rabbit IgG Log in to see Polyclonal

General

抗原 Stratifin (SFN) 抗体
适用 人, 小鼠, 大鼠
(197), (67), (52), (15), (14), (14), (11), (10), (8), (7), (5), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1)
宿主
(146), (36), (21), (2), (1)
克隆类型
多克隆
标记 This Stratifin antibody is conjugated to Alexa Fluor 350
(12), (9), (7), (7), (6), (6), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunofluorescence (Paraffin-embedded Sections) (IF (p))
(176), (81), (71), (50), (43), (21), (21), (18), (12), (4), (3), (3), (2), (1), (1)
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Stratifin抗体详情

Stratifin目标详情 使用细节 贮存及处理 图像
纯化方法 Purified by Protein A.
免疫原 KLH conjugated synthetic peptide derived from human 14-3-3 sigma
亚型 IgG

Stratifin目标详情

Stratifin抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 14-3-3 sigma (SFN Antibody 摘要)
背景

14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms, denoted 14-3-3 b, g, e, z, h, q and s, comprise this family of signaling intermediates. 14-3-3 s, also known as SFN, stratifin, HME1 or YWHAS, is a secreted adaptor protein that is involved in regulating both general and specific signaling pathways. Expressed predominately in stratified squamous keratinising epithelium, 14-3-3 s is able to bind and modify the activity of a large number of proteins, such as KRT17 (Keratin 17), through recognition of a phosphothreonine or phosphoserine motif. When bound to Keratin 17, for example, 14-3-3 s acts to stimulate the Akt/mTOR signaling pathway by upregulating protein synthesis and cell growth. 14-3-3 s also functions to positively mediate IGF-I-induced cell cycle progression and can bind to a variety of translation initiation factors, thus controlling mitotic translation. In response to tumor growth, 14-3-3 s positively regulates the tumor suppressor p53 and increases the rate of p53-regulated inhibition of G2/M cell cycle progression. Multiple isoforms of 14-3-3 s exist due to alternative splicing events.

Synonyms: 14 3 3 protein sigma, 14-3-3 protein sigma, 1433S_HUMAN, Epithelial cell marker protein 1, Er, HME 1, HME1, MGC143283, Mkrn3, Mme1, OTTHUMP00000004242, RP23 137L22.11, SFN, SFN protein, Stratin, YWHAS.

基因ID 2810
途径 p53 Pathway, Myometrial Relaxation and Contraction

使用细节

Stratifin抗体详情 Stratifin目标详情 贮存及处理 图像 回页首
应用备注 IF(IHC-P) 1:50-200
限制 仅限研究用

贮存及处理

Stratifin抗体详情 Stratifin目标详情 使用细节 图像 回页首
状态 Liquid
浓度 1 μg/μL
缓冲液 Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
储存条件 4 °C
储存方法 Store at 4°C
有效期 12 months