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Checkpoint with Forkhead and Ring Finger Domains 蛋白

(Checkpoint with Forkhead and Ring Finger Domains (CHFR))
E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the 'Lys-48'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. May also promote the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating ubc13-mms2 (ube2n-ube2v2) heterodimer. Substrates that are polyubiquitinated at 'Lys-63' are usually not targeted for degradation, but are rather involved in signaling cellular stress (By similarity).
CHFR Protein (AA 136-194) (GST tag) CHFR Protein (AA 136-194) (GST tag) CHFR Protein (AA 136-194) (GST tag) (ABIN1349314)

CHFR 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

CHFR Protein (AA 1-652) (GST tag) CHFR Protein (AA 1-652) (GST tag) CHFR Protein (AA 1-652) (GST tag) (ABIN1349312)

CHFR 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

CHFR Protein (AA 1-664) (His tag) CHFR Protein (AA 1-664) (His tag) CHFR Protein (AA 1-664) (His tag) (ABIN3091433)

Crystallography grade CHFR 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

Checkpoint with Forkhead and Ring Finger Domains 蛋白 by Grade

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Checkpoint with Forkhead and Ring Finger Domains 蛋白 by Origin

Find Checkpoint with Forkhead and Ring Finger Domains 蛋白 for a variety of species such as anti-Human Checkpoint with Forkhead and Ring Finger Domains, anti-Mouse Checkpoint with Forkhead and Ring Finger Domains. The species listed below are among those available. Click on a link to go to the corresponding products.

Checkpoint with Forkhead and Ring Finger Domains 蛋白 by Source

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Checkpoint with Forkhead and Ring Finger Domains 蛋白 by 蛋白类型

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Checkpoint with Forkhead and Ring Finger Domains 蛋白 by 应用范围

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Popular Checkpoint with Forkhead and Ring Finger Domains 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349314
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349312
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3091433
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136097
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2713969
Quantity 20 μg
Datasheet Datasheet

Aliases for Checkpoint with Forkhead and Ring Finger Domains 蛋白

checkpoint with forkhead and ring finger domains (CHFR) 蛋白
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase (chfr) 蛋白
checkpoint with forkhead and ring finger domains (Chfr) 蛋白
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase L homeolog (chfr.L) 蛋白
5730484M20Rik 蛋白
C230082M18 蛋白
CHFR 蛋白
fc43f10 蛋白
RNF116 蛋白
rnf116 蛋白
RNF196 蛋白
rnf196 蛋白
si:dkey-69h6.7 蛋白
wu:fc43f10 蛋白
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