CDKN1A (CDKN1A) ELISA试剂盒产品概述

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Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) ELISA试剂盒 (CDKN1A)
在www.antibodies-online.cn可供14 Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) ELISA试剂盒的9不同的供货商。 再加上,我们可以发CDKN1A 抗体 (577)CDKN1A 蛋白 (13)和数多这个蛋白质的别的产品。 总共641 CDKN1A产品已列进来了。
别名:
CAP20, CCND1, CDKI, Cdkn1, CDKN1A, CIP1, MDA-6, mda6, p16Xic2, P21, p21Cip1, p21WAF, SDI1, si:ch1073-48m5.2, UV96, WAF1
list all ELISA KIts 基因 基因ID UniProt
CDKN1A 114851  
CDKN1A 1026 P38936
CDKN1A 12575 P39689

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CDKN1A (CDKN1A) ELISA试剂盒 by Reactivity

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适于 CDKN1A 相互作用对的更多 ELISA 试剂盒

Zebrafish Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) interaction partners

  1. We characterized the effect of the novel loci through pathway analysis and found that pathways involved are not entirely distinct as assumed so far. Further, we identified a novel association between CDKN1A and POAG. Using a zebrafish model we show that six6b (associated with POAG and optic nerve head variation) alters the expression of cdkn1a

  2. intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (显示 CDK1 ELISA试剂盒), wee1 (显示 WEE1 ELISA试剂盒), p21, PCNA (显示 PCNA ELISA试剂盒) and cdk2 (显示 CDK2 ELISA试剂盒), but only weakly influences cyclin B1 (显示 CCNB1 ELISA试剂盒), cyclin B2 (显示 CCNB2 ELISA试剂盒) and cyclin E1 (显示 CCNE1 ELISA试剂盒) expression.

Human Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) interaction partners

  1. SUMO and p21Cip1 regulate the transit of proteins through the nucleolus; disruption of nucleolar export by DNA damage induces SUMO and p21Cip1 to act as hub proteins to form a multiprotein complex in the nucleolus.

  2. HULC activates p53 (显示 TP53 ELISA试剂盒)-p21 pathway and promotes nasopharyngeal carcinoma cell growth.

  3. We characterized the effect of the novel loci through pathway analysis and found that pathways involved are not entirely distinct as assumed so far. Further, we identified a novel association between CDKN1A and POAG. Using a zebrafish model we show that six6b (associated with POAG and optic nerve head variation) alters the expression of cdkn1a

  4. miRNAs miR (显示 MLXIP ELISA试剂盒)-106b and miR (显示 MLXIP ELISA试剂盒)-20a that target p21 were specifically downregulated in HIV-1 infected CD4 (显示 CD4 ELISA试剂盒)+ T cells.

  5. Increased nuclear localization of p21(WAF1/CIP1) in SPRY2 (显示 SPRY2 ELISA试剂盒) downregulated colon cancer cells may explain the inhibition of cell proliferation in colon cancer cells.

  6. This article discusses the controversial aspects of the two-faced involvement of p21 in cancer and speculate on how this new information may increase our understanding of its role in cancer pathogenesis. Prevailing notions indicate that p21 might also act as antiapoptotic agent, which may have relevant implications for future therapeutic strategies. [review]

  7. In this study, we found upregulation of several hemostasis-related genes, including the thrombin (显示 F2 ELISA试剂盒)-activatable receptor PAR-1 (protease-activated receptor-1 (显示 F2R ELISA试剂盒)), in Runx1 (显示 RUNX1 ELISA试剂盒)/Cbfb (显示 CBFB ELISA试剂盒)-deleted MLL (显示 MLL ELISA试剂盒)-AF9 (显示 MLLT3 ELISA试剂盒) cells. Similar to the effect of Runx1 (显示 RUNX1 ELISA试剂盒)/Cbfb (显示 CBFB ELISA试剂盒) deletion, PAR-1 (显示 MARK2 ELISA试剂盒) overexpression induced CDKN1A/p21 expression and attenuated proliferation in MLL (显示 MLL ELISA试剂盒)-AF9 (显示 MLLT3 ELISA试剂盒) cells

  8. Results provide evidence that Foxp3 (显示 FOXP3 ELISA试剂盒) is a downstream target of p53 (显示 TP53 ELISA试剂盒) and that is sufficient to induce p21 expression, ROS (显示 ROS1 ELISA试剂盒) production and p53 (显示 TP53 ELISA试剂盒)-mediated senescence.

  9. both in vitro and in vivo studies proved that CypD (显示 CYPD ELISA试剂盒) inhibitor-based treatment was able to efficiently impair this interaction, leading to a tumor formation reduction. All together, these findings indicate that the countering effect of CypD (显示 CYPD ELISA试剂盒) on the p53 (显示 TP53 ELISA试剂盒)-p21 pathway participates in oncogene (显示 RAB1A ELISA试剂盒)-dependent transformation.

  10. The deletion of CBX3 (显示 CBX3 ELISA试剂盒) directly enforces the expression of CDK6 (显示 CDK6 ELISA试剂盒) and p21.

Cow (Bovine) Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) interaction partners

  1. p21 expression reports on Bovine herpesvirus 4 replication and could represent a host cell defensive response to infection-associated cellular damage.

Mouse (Murine) Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A) interaction partners

  1. Data show that Emu-Myc (显示 MYC ELISA试剂盒) mice lacking both p21 and PUMA (显示 BBC3 ELISA试剂盒) developed lymphoma at a rate considerably longer latency than Emu-Myc (显示 MYC ELISA试剂盒);p53 (显示 TP53 ELISA试剂盒)(+/-)mice.

  2. Study reports that p27 (显示 CDKN1B ELISA试剂盒) normally exerts a negative feedback on p21 expression: p27 (显示 CDKN1B ELISA试剂盒) directly represses the expression of the transcription factor Pitx2 (显示 PITX2 ELISA试剂盒) which in turn maintains decreased p21 levels. Consequently, in cells lacking p27 (显示 CDKN1B ELISA试剂盒), de-repression of Pitx2 (显示 PITX2 ELISA试剂盒) causes the up-regulation of p21 showing a new mechanism by which p27 (显示 CDKN1B ELISA试剂盒) regulates cell cycle progression by transcriptionally regulating the expression of Pitx2 (显示 PITX2 ELISA试剂盒) and p21.

  3. p21-associated inhibition of early-stage malignant progression and the intense expression in papilloma outgrowths, identifies a novel, significant antagonism between p21 and ras(Ha)/ROCK2 (显示 ROCK2 ELISA试剂盒)/NF-kappaB (显示 NFKB1 ELISA试剂盒) signalling in skin carcinogenesis.these data show that ROCK2 (显示 ROCK2 ELISA试剂盒) activation induces malignancy in ras(Ha)-initiated/promoted papillomas in the context of p53 (显示 TP53 ELISA试剂盒) loss and novel NF-kappaB (显示 NFKB1 ELISA试剂盒) expression

  4. In this study, we found upregulation of several hemostasis-related genes, including the thrombin (显示 F2 ELISA试剂盒)-activatable receptor PAR-1 (protease-activated receptor-1 (显示 F2R ELISA试剂盒)), in Runx1 (显示 RUNX1 ELISA试剂盒)/Cbfb (显示 CBFB ELISA试剂盒)-deleted MLL (显示 MLL ELISA试剂盒)-AF9 (显示 MLLT3 ELISA试剂盒) cells. Similar to the effect of Runx1 (显示 RUNX1 ELISA试剂盒)/Cbfb (显示 CBFB ELISA试剂盒) deletion, PAR-1 (显示 MARK2 ELISA试剂盒) overexpression induced CDKN1A/p21 expression and attenuated proliferation in MLL (显示 MLL ELISA试剂盒)-AF9 (显示 MLLT3 ELISA试剂盒) cells

  5. both in vitro and in vivo studies proved that CypD (显示 CYPD ELISA试剂盒) inhibitor-based treatment was able to efficiently impair this interaction, leading to a tumor formation reduction. All together, these findings indicate that the countering effect of CypD (显示 CYPD ELISA试剂盒) on the p53 (显示 TP53 ELISA试剂盒)-p21 pathway participates in oncogene (显示 RAB1A ELISA试剂盒)-dependent transformation.

  6. FLT3 (显示 FLT3 ELISA试剂盒)-ITD is capable of inhibiting FLT3 (显示 FLT3 ELISA试剂盒)-ITD+ cell proliferation through the p21/Pbx1 (显示 PBX1 ELISA试剂盒) axis

  7. These data reveal a novel role for p21/waf1 in the resolution of inflammation via its ability to control neutrophil apoptosis.

  8. the silencing of Cyclin-dependent kinase 5 (显示 CDK5 ELISA试剂盒) preventing memory dysfunction

  9. Results show that p21 expression is regulated by OLA1 (显示 OLA1 ELISA试剂盒) to promote cell proliferation and organogenesis.

  10. AS160 regulates glucose-independent eukaryotic cell proliferation through p21-dependent control of the cell cycle.

CDKN1A 抗原简介

Antigen Summary

This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene.

Alternative names and synonyms associated with CDKN1A

  • cyclin-dependent kinase inhibitor 1A (p21, Cip1) (cdkn1a) Elisa Kit
  • cyclin-dependent kinase inhibitor 1 (cki1) Elisa Kit
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A) Elisa Kit
  • cyclin-dependent kinase inhibitor 1A (cdkn1a) Elisa Kit
  • cyclin-dependent kinase inhibitor 1A (LOC100348489) Elisa Kit
  • cyclin-dependent kinase inhibitor 1A (Cdkn1a) Elisa Kit
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1) (Cdkn1a) Elisa Kit
  • cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a) Elisa Kit
  • CAP20 Elisa Kit
  • CCND1 Elisa Kit
  • CDKI Elisa Kit
  • Cdkn1 Elisa Kit
  • CDKN1A Elisa Kit
  • CIP1 Elisa Kit
  • MDA-6 Elisa Kit
  • mda6 Elisa Kit
  • p16Xic2 Elisa Kit
  • P21 Elisa Kit
  • p21Cip1 Elisa Kit
  • p21WAF Elisa Kit
  • SDI1 Elisa Kit
  • si:ch1073-48m5.2 Elisa Kit
  • UV96 Elisa Kit
  • WAF1 Elisa Kit

Protein level used designations for CDKN1A

cyclin dependent kinase inhibitor p16Xic2 , cyclin-dependent kinase inhibitor 1 , cyclin D1 , cyclin-dependent kinase inhibitor 1A (p21, Cip1) , cip1 , p21 , waf1 , cyclin-dependent kinase inhibitor 1A , cyclin-dependent kinase inhibitor 1A (P21) , CDK-interacting protein 1 , CDK-interaction protein 1 , DNA synthesis inhibitor , melanoma differentiation associated protein 6 , wild-type p53-activated fragment 1 , p21/WAF1 , melanoma differentiation-associated protein , p21

GENE ID SPECIES
492305 Xenopus laevis
606440 Zea mays
747442 Pan troglodytes
100038054 Xenopus (Silurana) tropicalis
100302083 Ovis aries
100151416 Danio rerio
100348489 Oryctolagus cuniculus
114851 Rattus norvegicus
1026 Homo sapiens
474890 Canis lupus familiaris
513497 Bos taurus
100152215 Sus scrofa
100720449 Cavia porcellus
493943 Felis catus
12575 Mus musculus
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