电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

p21 抗体

(Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Multiple alternatively spliced variants have been found for this gene. [provided by RefSeq, Nov 2010].
p21 抗体  (AA 43-142) p21 抗体  (AA 43-142) p21 抗体 (AA 43-142) (ABIN3022006)

CDKN1A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

p21 抗体  (AA 65-164) p21 抗体  (AA 65-164) p21 抗体 (AA 65-164) (ABIN560309)

CDKN1A 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2F1 unconjugated

p21 抗体 p21 抗体 p21 抗体 (ABIN7255634)

CDKN1A 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

p21 抗体 by Grade

Find p21 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

p21 抗体 by 适用

Find p21 抗体 for a variety of species such as anti-Human p21, anti-Mouse p21, anti-Rat p21. The species listed below are among those available. Click on a link to go to the corresponding products.

p21 抗体 by 应用范围

Find p21 抗体 validated for a specific application such as WB, ELISA, FACS, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

p21 抗体 by 抗体来源

Find p21 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

p21 抗体 by 抗原表位

Find p21 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

p21 抗体 by 克隆形成能力

Find available monoclonal or polyclonal p21 抗体. Click on a link to go to the corresponding products.

p21 抗体 by 克隆

Find p21 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

p21 抗体 by 标记

Find p21 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular p21 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
  • (7)
Cat. No. ABIN3022006
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, PLA
Validations
  • (2)
  • (5)
Cat. No. ABIN560309
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (6)
Cat. No. ABIN7255634
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (7)
Cat. No. ABIN7266599
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7439048
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
  • (5)
Cat. No. ABIN7258160
Quantity 200 μL
Datasheet Datasheet
Reactivity Synthetic
Application WB, IHC (f)
Validations
  • (5)
Cat. No. ABIN7504137
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Non-Human Primate
Application ELISA, IHC (p), ICC
Validations
  • (2)
  • (4)
Cat. No. ABIN94444
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat, Sheep
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Validations
  • (2)
  • (3)
Cat. No. ABIN1714474
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN2854752
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IHC (f)
Validations
  • (4)
Cat. No. ABIN6939037
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
Cat. No. ABIN6256478
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, DB
Validations
  • (5)
Cat. No. ABIN3031122
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7148907
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (3)
  • (2)
Cat. No. ABIN6263942
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our p21 抗体

Lipskaia, Maisonnasse, Fouillade, Sencio, Pascal, Flaman, Born, London-Vallejo, Le Grand, Bernard, Trottein, Adnot: "Evidence that SARS-CoV-2 Induces Lung-Cell Senescence: Potential Impact on COVID-19 Lung Disease." in: American journal of respiratory cell and molecular biology, (2021) (PubMed).

Tang, Cao, Cai, An, Li, Peng, Chen, Luo, Tao, Li: "Epigallocatechin gallate induces chemopreventive effects on rats with diethylnitrosamine‑induced liver cancer via inhibition of cell division cycle 25A." in: Molecular medicine reports, Vol. 22, Issue 5, pp. 3873-3885, (2021) (PubMed).

Novais, Diekman, Shapiro, Risbud: "p16Ink4a deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence." in: Matrix biology : journal of the International Society for Matrix Biology, (2019) (PubMed).

Couture, Mora, Al Bittar, Najih, Touaibia, Martin: "Luteolin modulates gene expression related to steroidogenesis, apoptosis, and stress response in rat LC540 tumor Leydig cells." in: Cell biology and toxicology, (2019) (PubMed).

Ji, Zheng, Liu, Ren, Gao, Zhang, Li: "Resveratrol promotes oxidative stress to drive DLC1 mediated cellular senescence in cancer cells." in: Experimental cell research, Vol. 370, Issue 2, pp. 292-302, (2018) (PubMed).

Lin, Li, Ye, Chen, Zhang, Wang, Xi, Bu, Qiu: "LncRNA GACAT3 acts as a competing endogenous RNA of HMGA1 and alleviates cucurbitacin B-induced apoptosis of gastric cancer cells." in: Gene, (2018) (PubMed).

Guo, Zhao, Fei, Zhao, Zheng, Su, Wu, Li, Chang: "Dicer1 downregulation by multiple myeloma cells promotes the senescence and tumor-supporting capacity and decreases the differentiation potential of mesenchymal stem cells." in: Cell death & disease, Vol. 9, Issue 5, pp. 512, (2018) (PubMed).

He, Peng, Fan, Chen, Zheng, Li: "Cullin3/KCTD5 induces monoubiquitination of ΔNp63α and impairs its activity." in: FEBS letters, Vol. 592, Issue 13, pp. 2334-2340, (2018) (PubMed).

Aratani, Tagawa, Nagasaka, Sakai, Shimizu, Tsuruoka: "Radiation-induced premature cellular senescence involved in glomerular diseases in rats." in: Scientific reports, Vol. 8, Issue 1, pp. 16812, (2018) (PubMed).

Xiang, Yang, Xin, Gaertig, Reeves, Li, Li: "DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 7, pp. E1224-E1233, (2017) (PubMed).

Aliases for p21 抗体

cyclin D1 (CCND1) 抗体
cyclin dependent kinase inhibitor 1A (CDKN1A) 抗体
cyclin-dependent kinase inhibitor 1A (P21) (Cdkn1a) 抗体
cyclin-dependent kinase inhibitor 1A (Cdkn1a) 抗体
cyclin-dependent kinase inhibitor 1A L homeolog (cdkn1a.L) 抗体
cyclin-dependent kinase inhibitor 1 (cki1) 抗体
cyclin-dependent kinase inhibitor 1A (cdkn1a) 抗体
cyclin dependent kinase inhibitor 1A (Cdkn1a) 抗体
KRAS proto-oncogene, GTPase (KRAS) 抗体
CAP20 抗体
cap20 抗体
CCND1 抗体
CDKI 抗体
CDKN1 抗体
Cdkn1 抗体
cdkn1 抗体
CDKN1A 抗体
CIP1 抗体
Cip1 抗体
cip1 抗体
KRAS2 抗体
MDA-6 抗体
mda-6 抗体
mda6 抗体
p16Xic2 抗体
P21 抗体
p21 抗体
p21CIP1 抗体
p21Cip1 抗体
p21cip1 抗体
p21ras 抗体
p21WAF 抗体
SDI1 抗体
sdi1 抗体
si:ch1073-48m5.2 抗体
UV96 抗体
WAF1 抗体
Waf1 抗体
waf1 抗体
You are here:
客服