BAX 蛋白 (BAX)产品概述

Full name:
BCL2-Associated X Protein 蛋白 (BAX)
在www.antibodies-online.cn可供19 BCL2-Associated X Protein (BAX) 蛋白的9不同的供货商。 再加上,我们可以发BAX 抗体 (528)BAX 试剂盒 (71)和数多这个蛋白质的别的产品。 总共653 BAX产品已列进来了。
别名:
BAX, bax-A, BAX-ALPHA, BCL2L4, fj16e01, wu:fc50b10, wu:fj16e01, xBax, xlbax
列出全部蛋白 基因 基因ID UniProt
BAX 581 Q07812
BAX 12028 Q07813
大鼠 BAX BAX 24887  

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引用最多的BAX 蛋白

  1. Human BAX Protein expressed in Wheat germ - ABIN1346448 : Bras, Yuste, Roué, Barbier, Sancho, Virely, Rubio, Baudet, Esquerda, Merle-Béral, Sarfati, Susin: Drp1 mediates caspase-independent type III cell death in normal and leukemic cells. in Molecular and cellular biology 2007 (PubMed)

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Zebrafish BCL2-Associated X Protein (BAX) interaction partners

  1. These results suggest a role for mitochondrial p53 (显示 TP53 蛋白) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax and Bcl2 (显示 BCL2 蛋白).

Xenopus laevis BCL2-Associated X Protein (BAX) interaction partners

  1. xlbax is a regulator of muscle fiber death in the regressing tail during metamorphosis.

Cow (Bovine) BCL2-Associated X Protein (BAX) interaction partners

  1. BoHV-5 replication apparently modulates BCL-2 (显示 BCL2 蛋白) expression and gene transcription, enhancing production of virus progeny, but does not increase Bax expression.

  2. It was concluded that the Fas (显示 FAS 蛋白)-FasL (显示 FASL 蛋白) signaling pathway was involved in regulation of bovine oocyte apoptosis, perhaps related to B (显示 TDO2 蛋白) cell lymphoma/leukemia-2 associated X upregulation.

  3. apoptosis-inducing factor (显示 AIFM1 蛋白) was expressed in luminal alveolar cells and, in concert with a change in bax protein to bcl-2 (显示 BCL2 蛋白) protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses

  4. mRNA expression of Bax, Bcl-2 (显示 BCL2 蛋白), caspase-3 (显示 CASP3 蛋白) and-7 cannot be used as a reliable apoptosis detection method.

  5. The effect of culture conditions on expression of heat shock protein 70 (显示 HSP70 蛋白) and Bax protein in bovine blastocysts is reported.

Human BCL2-Associated X Protein (BAX) interaction partners

  1. An autoinhibited dimeric form of BAX regulates the cytosolic BAX activation pathway.

  2. Although TP53 (显示 TP53 蛋白) and BAX immunoreactivity levels were associated with some clinicopathological parameters of the patients, the expression of EP300 (显示 EP300 蛋白), TP53 (显示 TP53 蛋白) and BAX did not reveal any prognostic significance in ccRCC

  3. Cells expressing mitoCERT import ceramides into mitochondria and undergo Bax-dependent apoptosis.

  4. Recent studies that combine experiments in yeast and in mammalian cells have shown the unexpected effect of the anti-apoptotic protein Bcl-xL (显示 BCL2L1 蛋白) on the priming of Bax. As demonstrated with the BH3-mimetic molecule ABT-737, this property of Bcl-xL (显示 BCL2L1 蛋白), and of Bcl-2 (显示 BCL2 蛋白), is crucial to elaborate about how apoptosis could be reactivated in tumoral cells.

  5. Results support the hypothesis that the mitochondrion-specific lipid cardiolipin functions as a first contact site for Bax during its translocation to the mitochondrial outer membrane in the onset of apoptosis. In addition, dye leakage assays revealed that different oxidized phospholipids species in the mitochondrial outer membrane-mimicking vesicles can have opposing effects on Bax pore formation.

  6. These results not only establish Bok (显示 BOK 蛋白) as a Bak (显示 BAK1 蛋白)- and Bax-independent apoptosis inducer, but also suggest a potential impact of Bok (显示 BOK 蛋白) expression in ovarian cancer therapy.

  7. The substitution of proline 168 for alanine favors Bax oligomerization.

  8. Data show that the increased acetylation of Ku autoantigen 70kDa (Ku70 (显示 XRCC6 蛋白)) in sirtuin 6 (显示 SIRT6 蛋白) protein (SIRT6 (显示 SIRT6 蛋白))-depleted cells disrupt its interaction with Bax apoptosis regulator protein (Bax), which finally resulted in Bax mitochondrial translocalization.

  9. Rhaponticum carthamoides extracts from transformed and normal roots increased the ratio of Bax/Bcl-2 (显示 BCL2 蛋白) proteins and increased TP53 (显示 TP53 蛋白) levels to reduce glioma cell proliferation.

  10. these results indicate that EVA71 infection directly impacts the mitochondrial apoptotic pathway by modulating the recruitment and activation of Bax.

Mouse (Murine) BCL2-Associated X Protein (BAX) interaction partners

  1. An autoinhibited dimeric form of BAX regulates the cytosolic BAX activation pathway.

  2. Postnatal synaptic rearrangement needed for acquisition of skilled behaviors requires the activity-dependent, non-apoptotic Bax/Bak (显示 BAK1 蛋白)-caspase (显示 CASP3 蛋白) signaling cascade. Adult Bax/Bak (显示 BAK1 蛋白) mutant mice exhibit aberrant co-activation of antagonistic muscle pairs and skilled grasping deficits but normal reaching and retrieval behaviors.

  3. Study found that emphysema occurred in ku70(-/-) mice at the age of three-months old, and that Bax deficiency was able to suppress it. These results suggest that Bax-mediated apoptosis induces emphysema in ku70(-/-) mice.

  4. The polyglutamine embedded in the ER membrane was observed at the same time as Bax insertion. These results demonstrated that the ER membrane may be a target of polyglutamine, which triggers cell death through Bax.

  5. These results suggest that Bax mediates beta-cell apoptosis in Pdx1 (显示 PDX1 蛋白)-deficient diabetes.

  6. Bim (显示 BCL2L11 蛋白) and Puma (显示 BBC3 蛋白) overlapped apoptosis only partially during physiological apoptotic stage and they were present in non-apoptotic parts of the follicles.

  7. This study demonstated that Bax KO mice show Hyperactivity and depression.

  8. The influence of chronic ethanol consumption on the expression of the Bdnf (显示 BDNF 蛋白), Bax, Bcl-xL (显示 BCL2L1 蛋白), and CASP3 (显示 CASP3 蛋白) genes was studied in the brain structures of B6-1473C (C/C) and B6-1473G (G/G) mice that had been obtained on the base of the C57BL/6 strain.

  9. These data indicate that the rapid and robust microglial activation and PIF (显示 DCD 蛋白) expression observed in situ following acute EtOH exposure is largely driven indirectly by BAX-dependent apoptotic cell death, rather than directly by the EtOH.

  10. lipid profile in the absence of the proapoptotic proteins BAX and BAK (显示 BAK1 蛋白) in mouse embryonic fibroblasts

Pig (Porcine) BCL2-Associated X Protein (BAX) interaction partners

  1. Bid (显示 BID 蛋白) and Bax are signal transduction factors in granulosa cells and play proapoptotic roles.

  2. The data demonstrate that severe hypocapnia results in increased Bax expression, DNA fragmentation, and membrane lipid peroxidation in mitochondria of cerebral cortical neurons of newborn piglets, and may result in apoptotic cell death.

Guinea Pig BCL2-Associated X Protein (BAX) interaction partners

  1. bcl-2 (显示 BCL2 蛋白) and bax were expressed strongly in denervated guinea-pig facial muscle. [bcl-2 (显示 BCL2 蛋白); bax]

Goat BCL2-Associated X Protein (BAX) interaction partners

  1. goat oocytes based on G6PDH (显示 G6PD 蛋白)-activity through the BCB test improves their developmental competence, increases intracellular GSH content, and affects the expression of the apoptosis-related genes9 Bax and Bcl-2 (显示 BCL2 蛋白) ).

Rabbit BCL2-Associated X Protein (BAX) interaction partners

  1. The content of Bax protein in the cardiomyocyte cytoplasm decreased, thus indicating that the mitochondrial pathway was not involved in the realization of the apoptotic program in a model of ventricular overload.

  2. These results indicate that RI-PostC can ameliorate myocardial ischemia-reperfusion injury and increase the Bcl-2/Bax ratio through a mechanism involving protein kinase C.

  3. Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax and decreasing expression of bcl2 (显示 BCL2 蛋白).

  4. Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 (显示 BCL2 蛋白) and increased expression of Bax.

  5. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of BCL2-associated X protein (BAX) transcripts and protein depending on luteal stage.

蛋白简介BAX

蛋白简介

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.

Alternative names and synonyms associated with BAX

  • bcl2-associated X protein, a (baxa)
  • BCL2-associated X protein (bax)
  • BCL2-associated X protein (BAX)
  • BCL2-associated X protein (Bax)
  • Bcl2-associated X protein (Bax)
  • BCL2-associated X protein (LOC100355675)
  • BAX 蛋白
  • bax-A 蛋白
  • BAX-ALPHA 蛋白
  • BCL2L4 蛋白
  • fj16e01 蛋白
  • wu:fc50b10 蛋白
  • wu:fj16e01 蛋白
  • xBax 蛋白
  • xlbax 蛋白

Protein level used designations for BCL2-Associated X Protein 蛋白 (BAX)

zBax1 , bax zeta , apoptosis regulator BAX , BCL2-associated X protein , BCL2-associated X protein omega , BCL2-associated X protein transcript variant delta2 , bcl-2-like protein 4 , bcl2-L-4 , BCL2-associated protein

GENE ID SPECIES
58081 Danio rerio
373637 Xenopus laevis
394793 Xenopus (Silurana) tropicalis
493837 Felis catus
747093 Pan troglodytes
785708 Bos taurus
581 Homo sapiens
12028 Mus musculus
24887 Rattus norvegicus
403523 Canis lupus familiaris
280730 Bos taurus
396633 Sus scrofa
100730890 Cavia porcellus
100846984 Capra hircus
443059 Ovis aries
100355675 Oryctolagus cuniculus
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