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Human BAX ELISA Kit for Sandwich ELISA - ABIN365025
Zhou, Zhao, Ma, Ju, Li, Li, Sun, Shi, Zhang, Lu: The anticancer efficacy of paclitaxel liposomes modified with mitochondrial targeting conjugate in resistant lung cancer. in Biomaterials 2013
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Rat (Rattus) BAX ELISA Kit for Sandwich ELISA - ABIN416240
Fang, Yang, Yang, Chen: Chitosan oligosaccharides attenuates oxidative-stress related retinal degeneration in rats. in PLoS ONE 2013
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Mouse (Murine) BAX ELISA Kit for Sandwich ELISA - ABIN424766
Nakano, Marui, Muranaka, Masumoto, Noma, Tabata, Ido, Tsubouchi, Ikeda, Sakata: Effects of hepatocyte growth factor in myocarditis rats induced by immunization with porcine cardiac myosin. in Interactive cardiovascular and thoracic surgery 2014
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Mouse (Murine) BAX ELISA Kit for Sandwich ELISA - ABIN832356
Hao, Huang, Gu, Liu, Li, Liu, Ren, Yang, Peng, Wang, Li: Metallothionein deficiency aggravates depleted uranium-induced nephrotoxicity. in Toxicology and applied pharmacology 2015
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Rat (Rattus) BAX ELISA Kit for Sandwich ELISA - ABIN583629
Zhang, Feng, Gao, Sun, Wang, Li, Wang, Zhao, Hu, Sun, Wei, Sun: Role of pigment epithelium-derived factor (PEDF) in arsenic-induced cell apoptosis of liver and brain in a rat model. in Biological trace element research 2013
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Human BAX ELISA Kit for Sandwich ELISA - ABIN414428
Gornowicz, Bielawska, Czarnomysy, Gabryel-Porowska, Muszyńska, Bielawski: The combined treatment with novel platinum(II) complex and anti-MUC1 increases apoptotic response in MDA-MB-231 breast cancer cells. in Molecular and cellular biochemistry 2015
These results suggest a role for mitochondrial p53 (显示 TP53 ELISA试剂盒) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax and Bcl2 (显示 BCL2 ELISA试剂盒).
xlbax is a regulator of muscle fiber death in the regressing tail during metamorphosis.
BoHV-5 replication apparently modulates BCL-2 (显示 BCL2 ELISA试剂盒) expression and gene transcription, enhancing production of virus progeny, but does not increase Bax expression.
It was concluded that the Fas (显示 FAS ELISA试剂盒)-FasL (显示 FASL ELISA试剂盒) signaling pathway was involved in regulation of bovine oocyte apoptosis, perhaps related to B (显示 TDO2 ELISA试剂盒) cell lymphoma/leukemia-2 associated X upregulation.
apoptosis-inducing factor (显示 AIFM1 ELISA试剂盒) was expressed in luminal alveolar cells and, in concert with a change in bax protein to bcl-2 (显示 BCL2 ELISA试剂盒) protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses
mRNA expression of Bax, Bcl-2 (显示 BCL2 ELISA试剂盒), caspase-3 (显示 CASP3 ELISA试剂盒) and-7 cannot be used as a reliable apoptosis detection method.
The effect of culture conditions on expression of heat shock protein 70 (显示 HSP70 ELISA试剂盒) and Bax protein in bovine blastocysts is reported.
The C-terminal helical conformation of Bax, not its primary sequence, appears to be critical for CASP8 (显示 CASP8 ELISA试剂盒) recruitment and activation culminating in cell death.
An autoinhibited dimeric form of BAX regulates the cytosolic BAX activation pathway.
Although TP53 (显示 TP53 ELISA试剂盒) and BAX immunoreactivity levels were associated with some clinicopathological parameters of the patients, the expression of EP300 (显示 EP300 ELISA试剂盒), TP53 (显示 TP53 ELISA试剂盒) and BAX did not reveal any prognostic significance in ccRCC
Cells expressing mitoCERT import ceramides into mitochondria and undergo Bax-dependent apoptosis.
Recent studies that combine experiments in yeast and in mammalian cells have shown the unexpected effect of the anti-apoptotic protein Bcl-xL (显示 BCL2L1 ELISA试剂盒) on the priming of Bax. As demonstrated with the BH3-mimetic molecule ABT-737, this property of Bcl-xL (显示 BCL2L1 ELISA试剂盒), and of Bcl-2 (显示 BCL2 ELISA试剂盒), is crucial to elaborate about how apoptosis could be reactivated in tumoral cells.
Results support the hypothesis that the mitochondrion-specific lipid cardiolipin functions as a first contact site for Bax during its translocation to the mitochondrial outer membrane in the onset of apoptosis. In addition, dye leakage assays revealed that different oxidized phospholipids species in the mitochondrial outer membrane-mimicking vesicles can have opposing effects on Bax pore formation.
These results not only establish Bok (显示 BOK ELISA试剂盒) as a Bak (显示 BAK1 ELISA试剂盒)- and Bax-independent apoptosis inducer, but also suggest a potential impact of Bok (显示 BOK ELISA试剂盒) expression in ovarian cancer therapy.
The substitution of proline 168 for alanine favors Bax oligomerization.
Data show that the increased acetylation of Ku autoantigen 70kDa (Ku70 (显示 XRCC6 ELISA试剂盒)) in sirtuin 6 (显示 SIRT6 ELISA试剂盒) protein (SIRT6 (显示 SIRT6 ELISA试剂盒))-depleted cells disrupt its interaction with Bax apoptosis regulator protein (Bax), which finally resulted in Bax mitochondrial translocalization.
Rhaponticum carthamoides extracts from transformed and normal roots increased the ratio of Bax/Bcl-2 (显示 BCL2 ELISA试剂盒) proteins and increased TP53 (显示 TP53 ELISA试剂盒) levels to reduce glioma cell proliferation.
Postnatal synaptic rearrangement needed for acquisition of skilled behaviors requires the activity-dependent, non-apoptotic Bax/Bak (显示 BAK1 ELISA试剂盒)-caspase (显示 CASP3 ELISA试剂盒) signaling cascade. Adult Bax/Bak (显示 BAK1 ELISA试剂盒) mutant mice exhibit aberrant co-activation of antagonistic muscle pairs and skilled grasping deficits but normal reaching and retrieval behaviors.
Study found that emphysema occurred in ku70(-/-) mice at the age of three-months old, and that Bax deficiency was able to suppress it. These results suggest that Bax-mediated apoptosis induces emphysema in ku70(-/-) mice.
The polyglutamine embedded in the ER membrane was observed at the same time as Bax insertion. These results demonstrated that the ER membrane may be a target of polyglutamine, which triggers cell death through Bax.
These results suggest that Bax mediates beta-cell apoptosis in Pdx1 (显示 PDX1 ELISA试剂盒)-deficient diabetes.
Bim (显示 BCL2L11 ELISA试剂盒) and Puma (显示 BBC3 ELISA试剂盒) overlapped apoptosis only partially during physiological apoptotic stage and they were present in non-apoptotic parts of the follicles.
This study demonstated that Bax KO mice show Hyperactivity and depression.
The influence of chronic ethanol consumption on the expression of the Bdnf (显示 BDNF ELISA试剂盒), Bax, Bcl-xL (显示 BCL2L1 ELISA试剂盒), and CASP3 (显示 CASP3 ELISA试剂盒) genes was studied in the brain structures of B6-1473C (C/C) and B6-1473G (G/G) mice that had been obtained on the base of the C57BL/6 strain.
These data indicate that the rapid and robust microglial activation and PIF (显示 DCD ELISA试剂盒) expression observed in situ following acute EtOH exposure is largely driven indirectly by BAX-dependent apoptotic cell death, rather than directly by the EtOH.
lipid profile in the absence of the proapoptotic proteins BAX and BAK (显示 BAK1 ELISA试剂盒) in mouse embryonic fibroblasts
Bid (显示 BID ELISA试剂盒) and Bax are signal transduction factors in granulosa cells and play proapoptotic roles.
The data demonstrate that severe hypocapnia results in increased Bax expression, DNA fragmentation, and membrane lipid peroxidation in mitochondria of cerebral cortical neurons of newborn piglets, and may result in apoptotic cell death.
bcl-2 (显示 BCL2 ELISA试剂盒) and bax were expressed strongly in denervated guinea-pig facial muscle. [bcl-2 (显示 BCL2 ELISA试剂盒); bax]
goat oocytes based on G6PDH (显示 G6PD ELISA试剂盒)-activity through the BCB test improves their developmental competence, increases intracellular GSH content, and affects the expression of the apoptosis-related genes9 Bax and Bcl-2 (显示 BCL2 ELISA试剂盒) ).
The content of Bax protein in the cardiomyocyte cytoplasm decreased, thus indicating that the mitochondrial pathway was not involved in the realization of the apoptotic program in a model of ventricular overload.
These results indicate that RI-PostC can ameliorate myocardial ischemia-reperfusion injury and increase the Bcl-2 (显示 BCL2 ELISA试剂盒)/Bax ratio through a mechanism involving protein kinase C (显示 PKC ELISA试剂盒).
Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax and decreasing expression of bcl2 (显示 BCL2 ELISA试剂盒).
Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 (显示 BCL2 ELISA试剂盒) and increased expression of Bax.
In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of BCL2-associated X protein (BAX) transcripts and protein depending on luteal stage.
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
, bax zeta
, apoptosis regulator BAX
, BCL2-associated X protein
, BCL2-associated X protein omega
, BCL2-associated X protein transcript variant delta2
, bcl-2-like protein 4
, BCL2-associated protein