anti-大鼠 ATM 抗体 for Immunofluorescence

Recommended ATM Antibody (supplied by: Log in to see )

抗原
Ataxia Telangiectasia Mutated (ATM) 抗体
  • ATM
  • Atm
  • CG6535
  • Dmel\\CG6535
  • Tefu
  • atm
  • atm/tefu
  • dATM
  • tef
  • Xatm
  • at1
  • atdc
  • tel1
  • telo1
  • AT1
  • ATA
  • ATC
  • ATD
  • ATDC
  • ATE
  • TEL1
  • TELO1
  • AI256621
  • C030026E19Rik
  • telomere fusion
  • ataxia telangiectasia mutated
  • ataxia telangiectasia mutated (atm)
  • ataxia telangiectasia mutated homolog (human)
  • tefu
  • atm
  • ATM
  • EDI_100660
  • CpipJ_CPIJ001772
  • BDBG_08252
  • PAAG_02532
  • MCYG_05088
  • VDBG_06833
  • ACLA_015700
  • AaeL_AAEL014900
  • MGYG_07634
  • PGTG_14279
  • Atm
  • LOC100349299
适用
人, 猴, 小鼠, 大鼠
359
157
77
26
8
1
1
1
1
宿主
小鼠
234
98
17
9
3
克隆类型
单克隆
标记
This ATM antibody is un-conjugated
12
11
10
9
6
6
5
5
5
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
应用范围
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
219
125
110
88
85
71
58
45
27
21
13
6
4
4
2
2
2
1
1
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产品编号 ABIN151622
产品在该地区无法提供。
获取报价
中国 北京 101111
No. 88 KeChuang 6th Street
Room 801-803
Beijing Economic Technological Development Area
4A Biotech Co.,Ltd.
Tel 400-7060-959
传真 +86 10 56315212-8813
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN151772 ICC IF IHC (p) IP IHC WB Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12 19
1 ABIN151775 ChIP ELISA FACS ICC IF IHC IHC (p) IP WB Mouse IgG1 full length Log in to see 2C1 114
1 ABIN1721771 ICC IF IHC WB Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282170 ICC IF IHC IHC (p) WB DyLight 650 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282169 ICC IF IHC IHC (p) WB Biotin Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282173 ICC IF IHC IHC (p) WB DyLight 550 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282171 ICC IF IHC IHC (p) WB DyLight 488 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282175 ICC IF IHC IHC (p) FITC Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282178 ICC IF IHC IHC (p) WB DyLight 405 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282179 ICC IF IHC IHC (p) WB DyLight 350 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282190 ICC IF IHC IHC (p) WB DyLight 680 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282188 ICC IF IHC IHC (p) WB DyLight 755 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282184 ICC IF IHC IHC (p) IP WB PerCP Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282200 ICC IF IHC IHC (p) WB Alexa Fluor 488 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282201 ICC IF IHC IHC (p) WB Alexa Fluor 647 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282202 ICC IF IHC IHC (p) WB Alexa Fluor 700 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282199 ICC IF IHC IHC (p) WB Alexa Fluor 405 Mouse IgG1 kappa pSer1981 Log in to see 10H11-E12
1 ABIN4282181 ELISA FACS ICC IF IHC IHC (p) WB DyLight 405 Mouse IgG1 full length Log in to see 2C1
1 ABIN4282185 ELISA ICC IF IHC IHC (p) IP WB PerCP Mouse IgG1 full length Log in to see 2C1
1 ABIN4282180 ELISA FACS ICC IF IHC IHC (p) WB DyLight 350 Mouse IgG1 full length Log in to see 2C1

General

抗原 Ataxia Telangiectasia Mutated (ATM) 抗体
适用 人, 猴, 小鼠, 大鼠
(359), (157), (77), (26), (8), (1), (1), (1), (1)
宿主 小鼠
(234), (98), (17), (9), (3)
克隆类型 (克隆位点)
单克隆   ( )
标记 This ATM antibody is un-conjugated
(12), (11), (10), (9), (6), (6), (5), (5), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
应用范围 Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blotting (WB)
(219), (125), (110), (88), (85), (71), (58), (45), (27), (21), (13), (6), (4), (4), (2), (2), (2), (1), (1)
Pubmed 20个引用可参考
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ATM抗体详情

ATM目标详情 使用细节 贮存及处理 ProductDetails: References for anti-ATM antibody (ABIN151622) 图像
纯化方法 Protein G purified
免疫原 Recombinant protein expressed in E. coli corresponding to amino acids 980-1512.
克隆位点 5C2
亚型 IgG1

ATM目标详情

ATM抗体详情 使用细节 贮存及处理 ProductDetails: References for anti-ATM antibody (ABIN151622) 图像 回页首
抗原
别名 ATM (ATM Antibody 摘要)
背景 Gene Symbol: ATM
分子量 Theoretical MW: 370 kDa
基因ID 472
研究领域 Cancer, DNA/RNA
途径 p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus

使用细节

ATM抗体详情 ATM目标详情 贮存及处理 ProductDetails: References for anti-ATM antibody (ABIN151622) 图像 回页首
应用备注 Western Blot 1:500-1:3000, Immunohistochemistry 1:10 - 1:500, Immunocytochemistry/Immunofluorescence 1:100-1:1000, Immunoprecipitation 1:10 - 1:500IHC usage reported in scientific literature (PMID: 21095582). WB: Predicated molecular weight: 350 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
说明

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

限制 仅限研究用

贮存及处理

ATM抗体详情 ATM目标详情 使用细节 ProductDetails: References for anti-ATM antibody (ABIN151622) 图像 回页首
状态 Liquid
浓度 2.43 mg/mL
缓冲液 PBS
Buffer contains: No Preservative
储存液 Without preservative
注意事项 Avoid freeze-thaw cycles
储存条件 -80 °C,-20 °C
储存方法 Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

ProductDetails: References for anti-ATM antibody (ABIN151622)

ATM抗体详情 ATM目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Barnard, Regan, Hansen, Maycotte, Thorburn, Gustafson: "Autophagy Inhibition Delays Early but Not Late-Stage Metastatic Disease." in: The Journal of pharmacology and experimental therapeutics, Vol. 358, Issue 2, pp. 282-93, 2016 Method employed by authors: Flow Cytometry (FACS)

Aumailley, Garand, Dubois, Johnson, Marette, Lebel: "Metabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null Mice." in: PLoS ONE, Vol. 10, Issue 10, pp. e0140292, 2015 (Sample species: Mouse (Murine)). Further details: Immunocytochemistry,Immunofluorescence

Milan, Perini, Resnati, Orfanelli, Oliva, Raimondi, Cascio, Bachi, Marcatti, Ciceri, Cenci: "A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells." in: Autophagy, Vol. 11, Issue 7, pp. 1161-78, 2015

Hou, Toh, Wang: "NBS1 deficiency promotes genome instability by affecting DNA damage signaling pathway and impairing telomere integrity." in: Cell biochemistry and function, Vol. 30, Issue 3, pp. 233-42, 2012

Mendez, Cilli, Berardinelli, Viganotti, Ascenzi, Tanzarella, Antoccia, di Masi: "Cleavage of the BRCT tandem domains of nibrin by the 657del5 mutation affects the DNA damage response less than the Arg215Trp mutation." in: IUBMB life, Vol. 64, Issue 10, pp. 853-61, 2012

Rankin, Sarkar, Faller: "Mechanism of T-oligo-induced cell cycle arrest in Mia-PaCa pancreatic cancer cells." in: Journal of cellular physiology, Vol. 227, Issue 6, pp. 2586-94, 2012 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Daniel, Pellegrini, Lee, Guo, Filsuf, Belkina, You, Paull, Sleckman, Feigenbaum, Nussenzweig: "Loss of ATM kinase activity leads to embryonic lethality in mice." in: The Journal of cell biology, Vol. 198, Issue 3, pp. 295-304, 2012 (Sample species: Mouse (Murine)). Further details: Western Blotting

Gapud, Dorsett, Yin, Callen, Bredemeyer, Mahowald, Omi, Walker, Bednarski, McKinnon, Bassing, Nussenzweig, Sleckman: "Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 5, pp. 2022-7, 2011 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Vogel, Seyffert, Strasser, de Oliveira, Dresch, Glauser, Jolinon, Salvetti, Weitzman, Ackermann, Fraefel: "Adeno-associated virus type 2 modulates the host DNA damage response induced by herpes simplex virus 1 during coinfection." in: Journal of virology, Vol. 86, Issue 1, pp. 143-55, 2011 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Alimonti, Nardella, Chen, Clohessy, Carracedo, Trotman, Cheng, Varmeh, Kozma, Thomas, Rosivatz, Woscholski, Cognetti, Scher, Pandolfi: "A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis." in: The Journal of clinical investigation, Vol. 120, Issue 3, pp. 681-93, 2010

Craig, Holcakova, Finlan, Nekulova, Hrstka, Gueven, DiRenzo, Smith, Hupp, Vojtesek: "DeltaNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation." in: Molecular cancer, Vol. 9, pp. 195, 2010 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Cam, Easton, High, Houghton: "mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α." in: Molecular cell, Vol. 40, Issue 4, pp. 509-20, 2010 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Efeyan, Murga, Martinez-Pastor, Ortega-Molina, Soria, Collado, Fernandez-Capetillo, Serrano: "Limited role of murine ATM in oncogene-induced senescence and p53-dependent tumor suppression." in: PLoS ONE, Vol. 4, Issue 5, pp. e5475, 2009 (Sample species: Mouse (Murine)). Further details: Western Blotting

Gonzalez-Suarez, Redwood, Perkins, Vermolen, Lichtensztejin, Grotsky, Morgado-Palacin, Gapud, Sleckman, Sullivan, Sage, Stewart, Mai, Gonzalo: "Novel roles for A-type lamins in telomere biology and the DNA damage response pathway." in: The EMBO journal, Vol. 28, Issue 16, pp. 2414-27, 2009 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Siehler, Schrauder, Gerischer, Cantor, Marra, Wiesmüller: "Human MutL-complexes monitor homologous recombination independently of mismatch repair." in: DNA repair, Vol. 8, Issue 2, pp. 242-52, 2009 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Ariumi, Kuroki, Dansako, Abe, Ikeda, Wakita, Kato: "The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replication." in: Journal of virology, Vol. 82, Issue 19, pp. 9639-46, 2008 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Fernandes, Sun, Price: "Activation of the kinase activity of ATM by retinoic acid is required for CREB-dependent differentiation of neuroblastoma cells." in: The Journal of biological chemistry, Vol. 282, Issue 22, pp. 16577-84, 2007 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Sun, Xu, Roy, Price: "DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity." in: Molecular and cellular biology, Vol. 27, Issue 24, pp. 8502-9, 2007 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Shiotani, Kobayashi, Watanabe, Yamamoto, Sugimura, Wakabayashi: "Involvement of the ATR- and ATM-dependent checkpoint responses in cell cycle arrest evoked by pierisin-1." in: Molecular cancer research : MCR, Vol. 4, Issue 2, pp. 125-33, 2006 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

Jiang, Sun, Chen, Roy, Price: "The FATC domains of PIKK proteins are functionally equivalent and participate in the Tip60-dependent activation of DNA-PKcs and ATM." in: The Journal of biological chemistry, Vol. 281, Issue 23, pp. 15741-6, 2006 (Sample species: Human). Further details: Immunocytochemistry,Immunofluorescence

图像

ATM抗体详情 ATM目标详情 使用细节 贮存及处理 ProductDetails: References for anti-ATM antibody (ABIN151622) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) antibody (ABIN151622) Detection of human ATM protein using ATM 5C2 monoclonal antibody (ABIN151622) in Raji...
Western Blotting (WB) image for anti-Ataxia Telangiectasia Mutated (ATM) antibody (ABIN151622) Western Blot: ATM Antibody (5C2) [ABIN151622] - HeLa whole cell extracts and nuclear ...
Immunofluorescence (IF) image for anti-Ataxia Telangiectasia Mutated (ATM) antibody (ABIN151622) Immunocytochemistry/Immunofluorescence: ATM Antibody (5C2) [ABIN151622] - HeLa cells ...