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Human Survivin ELISA Kit for Sandwich ELISA - ABIN415309
Nigam, Chandra, Kazmi, Singh, Gupta, Parmar, Srivastava: Expression of serum survivin protein in diagnosis and prognosis of gallbladder cancer: a comparative study. in Medical oncology (Northwood, London, England) 2014
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Mouse (Murine) Survivin ELISA Kit for Sandwich ELISA - ABIN426193
Donskow-?ysoniewska, Brodaczewska, Doligalska: Heligmosomoides polygyrus antigens inhibit the intrinsic pathway of apoptosis by overexpression of survivin and Bcl-2 protein in CD4 T cells. in Prion 2013
survivin expression modes and YAP (显示 YAP1 ELISA试剂盒) localization (Hippo pathway activation modes) were not correlated with survival. In addition, we confirmed that survivin small interference RNA (siRNA) transfection and YM155, an anti-survivin drug, elicited decreased nuclear survivin expression and cell proliferation in ISO-HAS-B cells which expressed survivin consistently
Survivin expression in lung squamous cell carcinoma was increased compared to normal tissue, and was unaffected by methylation status of the surviving gene.
Survivin gene promoter methylation was more frequent in gastric cancer patients than in controls.
These findings uncover the significance of Merlin (显示 NF2 ELISA试剂盒) protein expression and Survivin labeling index as prognosticators for poor clinical outcome in two independent Malignant pleural mesothelioma cohorts.
circulating Survivin in prostate cancer patients was higher compared to controls, with the highest levels in African-American (AA) patients. AA patients with prostate cancer contained higher amounts of extracellular vesicles (EVs) in their plasma and sera than European-American (EA) patients. EVs from AA patients with prostate cancer contained higher amounts of Survivin, XIAP (显示 XIAP ELISA试剂盒) and cIAP-2 (显示 BIRC3 ELISA试剂盒) than EVs from EA patients.
results indicate that survivin is of prognostic signi fi cance in patients with renal cell carcinoma
The aim of this study was to compare the prognostic value of the histopathological grading and the conventional biomarker MIB-1 with expression of the anti-apoptotic protein survivin to see if this biomarker could complement recurrence prediction.
Data suggest that the first 22 bp of exon 3 in BIRC5 contain cis (显示 CISH ELISA试剂盒)-acting elements that enhance the exclusion of exon 3 to generate the survivin DEx3 mRNA isoform via exclusion/deletion of exon 3; Sam68 (显示 KHDRBS1 ELISA试剂盒) is a possible trans-acting factor that binds to this cis (显示 CISH ELISA试剂盒)-acting element and regulates exon 3 splicing. (BIRC5/survivin = baculoviral IAP repeat containing 5; Sam68 (显示 KHDRBS1 ELISA试剂盒) = GAP-associated tyrosine phosphoprotein p62 (显示 KHDRBS1 ELISA试剂盒))
our data suggest the existence of a novel pre-metastatic phase quiescent-breast cancer stem cells (Q-BCSCs) before epithelial to mesenchymal transition and SURVIVIN acts as a marker for Quiescent-BCSCs
Expressions of SDF-1 (显示 CXCL12 ELISA试剂盒), survivin and smac (显示 DIABLO ELISA试剂盒) were significantly higher in epithelial ovarian cancer tissue than those in normal tissue.
HDL (显示 HSD11B1 ELISA试剂盒)-associated sphingosine 1-phosphate inhibits macrophage apoptosis by stimulating STAT3 (显示 STAT3 ELISA试剂盒) activity and survivin expression.
Survivin also attenuates DNA damage related to PARP (显示 PARP1 ELISA试剂盒) activation and inhibits TNFalpha (显示 TNF ELISA试剂盒)-induced lipolysis, suggesting that Survivin may facilitate adipocyte maintenance in response to inflammatory stimuli.
The study assigns a new meiotic function to Cullin9 and reveals that it prevents mouse eggs from aneuploidy by regulating microtubule dynamics via survivin.
this study shows that that sorafenib promotes the survival of bone marrow cells by up-regulating survivin
Survivin was regulated by TGF-beta (显示 TGFB1 ELISA试剂盒) and was found to be highly expressed during mucosal healing following intestinal inflammation
Survivin is a key regulator of gut (显示 GUSB ELISA试剂盒) tissue integrity by regulating epithelial homeostasis in the stem cell niche.
TGFbetaRI inhibition in an injured adult heart could both stimulate the autocrine/paracrine activity of survivin and inhibit Wnt (显示 WNT2 ELISA试剂盒) in CPCs to mediate cardioprotection and improve cardiac function.
Survivin is a key gene for regulating squamous cell carcinoma (SCC (显示 CYP11A1 ELISA试剂盒)) cancer stem cell formation and cancer SCC (显示 CYP11A1 ELISA试剂盒) development.
In colorectal cancer mice with downregulated expression of survivin, there were higher numbers of apoptotic cells and decreased expression levels of bcl2 (显示 BCL2 ELISA试剂盒) and ki67 (显示 MKI67 ELISA试剂盒).
survivin is essential for B cell division but does not affect survival of naive B cells. Survival of proliferating B cells may be impacted indirectly by survivin deficiency because of increased genotoxic stress caused by failed chromosomal segregation.
The present studies aim to examine whether and how cilia function (Pkd1 (显示 PKD1 ELISA试剂盒) or Pkd2 (显示 PKD2 ELISA试剂盒)) and structure (Tg737 (显示 IFT88 ELISA试剂盒)) play a role in cystic kidney and aneurysm through survivin downregulation.
Survivin 1 was identified as a key regulator of neurogenesis, vasculo-angiogenesis, hematopoiesis and cardiogenesis.
the Aurora B (显示 AURKB ELISA试剂盒) chromosome passenger protein complex, including INCENP (显示 INCENP ELISA试剂盒) and survivin, is regulated during oocyte maturation in Xenopus laevis
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
apoptosis inhibitor survivin
, baculoviral IAP repeat-containing 5
, baculoviral IAP repeat-containing protein 5
, baculoviral IAP repeat-containing 5 (survivin)
, apoptosis inhibitor 4
, survivin variant 3 alpha
, survivin 1
, baculoviral IAP repeat-containing protein 5.1
, Survivin 2
, baculoviral IAP repeat-containing 5, gene 2
, baculoviral IAP repeat-containing protein 5.2