RBPJ (RBPJ) ELISA试剂盒产品概述

在www.antibodies-online.cn可供0 Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) ELISA试剂盒的不同的供货商。 再加上,我们可以发RBPJ 抗体 (86)RBPJ 蛋白 (8)和数多这个蛋白质的别的产品。 总共100 RBPJ产品已列进来了。
别名:
AI843960, AOS3, CBF1, csl, Igkjrb, IGKJRB1, Igkrsbp, KBF2, RBP-J, RBP-J kappa, RBPjk, Rbpsuh, Su(H), SUH, XSu(H), xsu(h)1
list all ELISA KIts 基因 基因ID UniProt
大鼠 RBPJ RBPJ 679028  
 RBPJ RBPJ 3516 Q06330
小鼠 RBPJ RBPJ 19664 P31266

适于 RBPJ 相互作用对的更多 ELISA 试剂盒

Human Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) interaction partners

  1. RBPJ links MYC (显示 MYC ELISA试剂盒) and transcriptional control through CDK9 (显示 CDK9 ELISA试剂盒) in brain tumors, providing potential nodes of fragility for therapeutic intervention, potentially distinct from NOTCH (显示 NOTCH1 ELISA试剂盒)

  2. Mean CBF1 expression is significantly increased in isocitrate dehydrogenase 1 (IDH1 (显示 IDH1 ELISA试剂盒)) R132H mutant glioblastoma. Hypoxic regions of glioblastoma have higher CBF1 activation and exposure to low oxygen can induce its expression in glioma cells in vitro.

  3. structural and biophysical studies demonstrate that RITA (显示 ZNF331 ELISA试剂盒) binds RBP-J similarly to the RAM (显示 RAB27A ELISA试剂盒) (RBP-J-associated molecule) domain of Notch (显示 NOTCH1 ELISA试剂盒), our biochemical and cellular assays suggest that RITA (显示 ZNF331 ELISA试剂盒) interacts with additional regions in RBP-J.

  4. The present findings indicate that p53 (显示 TP53 ELISA试剂盒), in turn, decreases CSL expression, which can serve to enhance p53 (显示 TP53 ELISA试剂盒) activity in acute DNA damage response of cells.

  5. RBP-J mediated by miR (显示 MLXIP ELISA试剂盒)-133a probably contributed to the regulation of DCs maturation and activation in osteosarcoma

  6. These results suggest that PSK (显示 TAOK2 ELISA试剂盒) suppresses Hedgehog (显示 SHH ELISA试剂盒) signaling through down-regulation of MAML3 and RBPJ transcription under hypoxia, inhibiting the induction of a malignant phenotype in pancreatic cancer. Our results may lead to development of new treatments for refractory pancreatic cancer using PSK (显示 TAOK2 ELISA试剂盒) as a Hedgehog (显示 SHH ELISA试剂盒) inhibitor

  7. our findings reconcile the 2 biological events and point to a multistep process of CAF (显示 KAT2B ELISA试剂盒) activation under convergent CSL and p53 (显示 TP53 ELISA试剂盒) control. Activation of p53 (显示 TP53 ELISA试剂盒) provides a failsafe mechanism against consequences of compromised CSL activity in stromal cells.

  8. RBPJ polymorphism [rs874040(CC) allele] skews memory T cells toward a pro-inflammatory phenotype involving Notch (显示 NOTCH1 ELISA试剂盒) signaling, thus increasing the susceptibility to develop rheumatoid arthritis.

  9. The role of CSL-dependent and independent Notch (显示 NOTCH1 ELISA试剂盒) signaling pathways in cell apoptosis is described in normal tissue homeostasis and in tumorigenesis. (Review)

  10. These results support a model in which EBNA2 and EBNA3s compete for distinct subsets of RBPJ sites to regulate cell genes and where EBNA3 subset specificity is determined by interactions with other cell transcription factors.

Xenopus laevis Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) interaction partners

  1. findings reveal that, in response to Wnt (显示 WNT2 ELISA试剂盒) signalling, Dishevelled (显示 DVL2 ELISA试剂盒) inhibits CSL (显示 SMPX ELISA试剂盒) transcription factors to regulate Notch (显示 NOTCH1 ELISA试剂盒) signalling and cell-fate decisions in vivo

  2. The study reports the identification and functional characterization of rbpj interacting and tubulin associated (RITA) (C12ORF52 (显示 C12orf52 ELISA试剂盒)) as a novel rbpj/CBF-1-interacting protein.

  3. The results suggest that a cell-to-cell interaction via the Notch (显示 NOTCH1 ELISA试剂盒)/Su(H) pathway has a significant role in the PGC (显示 PGC ELISA试剂盒) migration by regulating cell motility.

  4. This "target protector and rescue assay" demonstrates that the phenotypic defects associated with CUGBP1 inactivation in Xenopus are essentially due to the deregulation of Su(H) mRNA.

Mouse (Murine) Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) interaction partners

  1. RBP-J-mediated Notch (显示 NOTCH1 ELISA试剂盒) signalling is critical for basophil-dependent immunoregulation. Deficiency of RBP-J influences the immunoregulatory functions of BA, which include activation of T cells and their differentiation into T helper cell subtypes.

  2. Data, including data from studies using cells from transgenic/knockout mice, suggest that Med1 (显示 MBD4 ELISA试剂盒) plays role in enamel formation; Med1 (显示 MBD4 ELISA试剂盒) induces Alpl (显示 ALPL ELISA试剂盒) via stimulation of Notch1 (显示 NOTCH1 ELISA试剂盒) signaling by forming Notch1 (显示 NOTCH1 ELISA试剂盒)-RBP-Jk complex on Alpl (显示 ALPL ELISA试剂盒) promoter. (Med1 (显示 MBD4 ELISA试剂盒) = mediator complex subunit 1 (显示 MED1 ELISA试剂盒); Alpl (显示 ALPL ELISA试剂盒) = alkaline phosphatase, liver-bone-kidney; Notch1 (显示 NOTCH1 ELISA试剂盒) = Notch gene homolog 1 (显示 NOTCH1 ELISA试剂盒); RBP-Jk = kappa J region recombining binding protein suppressor of hairless)

  3. study uncovered a regulatory network, where miR (显示 MLXIP ELISA试剂盒)-182 functions as an important new node that receives inputs from RBP-J and TNF-alpha (显示 TNF ELISA试剂盒) signaling and positively regulates inflammatory osteoclastogenesis; suppression of miR (显示 MLXIP ELISA试剂盒)-182 by RBP-J serves as an important mechanism that restrains TNF-alpha (显示 TNF ELISA试剂盒) induced osteoclastogenesis

  4. structural and biophysical studies demonstrate that RITA (显示 C12orf52 ELISA试剂盒) binds RBP-J similarly to the RAM (RBP-J-associated molecule) domain of Notch (显示 NOTCH1 ELISA试剂盒), our biochemical and cellular assays suggest that RITA (显示 C12orf52 ELISA试剂盒) interacts with additional regions in RBP-J.

  5. Intronic Flk1 (显示 KDR ELISA试剂盒) genetic enhancer element directs arterial-specific expression via RBPJ-mediated venous repression.

  6. RBP-J mediated by miR (显示 MLXIP ELISA试剂盒)-133a probably contributed to the regulation of DCs maturation and activation in osteosarcoma

  7. Rbpj-kappa mediated Notch (显示 NOTCH1 ELISA试剂盒) signaling plays a critical role in development of hypothalamic Kisspeptin neurons.

  8. Results reveal an essential role for canonical Notch (显示 NOTCH1 ELISA试剂盒)/RBP-J signaling in hippocampal synaptic plasticity and suggest that role, at least in part, is mediated by the regulation of GABAergic signaling

  9. The bone marrow contains a progenitor that expresses renin (显示 REN ELISA试剂盒) throughout development and possesses a B-lymphocyte (显示 AKAP17A ELISA试剂盒) pedigree. This cell requires RBP-J to differentiate.

  10. functions as a transcriptional repressor on the promoter of the microRNA miR (显示 MLXIP ELISA试剂盒)-155

RBPJ 抗原简介

Antigen Summary

The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.

Alternative names and synonyms associated with RBPJ

  • recombination signal binding protein for immunoglobulin kappa J region (Rbpj) Elisa Kit
  • recombination signal binding protein for immunoglobulin kappa J region (RBPJ) Elisa Kit
  • recombination signal binding protein for immunoglobulin kappa J region (rbpj) Elisa Kit
  • AI843960 Elisa Kit
  • AOS3 Elisa Kit
  • CBF1 Elisa Kit
  • csl Elisa Kit
  • Igkjrb Elisa Kit
  • IGKJRB1 Elisa Kit
  • Igkrsbp Elisa Kit
  • KBF2 Elisa Kit
  • RBP-J Elisa Kit
  • RBP-J kappa Elisa Kit
  • RBPjk Elisa Kit
  • Rbpsuh Elisa Kit
  • Su(H) Elisa Kit
  • SUH Elisa Kit
  • XSu(H) Elisa Kit
  • xsu(h)1 Elisa Kit

Protein level used designations for RBPJ

recombining binding protein suppressor of hairless , CBF-1 , H-2K binding factor-2 , RBP-J kappa , RBP-JK , immunoglobulin kappa J region recombination signal binding protein 1 , renal carcinoma antigen NY-REN-30 , suppressor of hairless homolog , X-Su(H) , suppressor of hairless protein 1 , suppressor of hairless protein homolog , J kappa-recombination signal-binding protein

GENE ID SPECIES
679028 Rattus norvegicus
3516 Homo sapiens
399453 Xenopus laevis
19664 Mus musculus
767928 Bos taurus
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