anti-Notch1 (NOTCH1) 抗体产品概述

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anti-Notch 1 抗体 (NOTCH1)
在www.antibodies-online.cn可供389 Notch 1 (NOTCH1) 抗体的34不同的供货商。 再加上,我们可以发Notch1 试剂盒 (22)Notch1 蛋白 (12)和数多这个蛋白质的别的产品。 总共436 Notch1产品已列进来了。
别名:
9930111A19Rik, hN1, lin-12, Mis6, N1, NOTCH, notch-1, NOTCH1, notch1-a, Tan1, xnotch, xnotch1, Xotch
列出全部抗体 基因 基因ID UniProt
NOTCH1 4851 P46531
NOTCH1 18128 Q01705
NOTCH1 25496  

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引用最多的anti-Notch1 抗体

  1. Human Monoclonal Notch1 Primary Antibody for FACS, IHC (fro) - ABIN181989 : Dass, Choong: Zoledronic acid inhibits osteosarcoma growth in an orthotopic model. in Molecular cancer therapeutics 2007 (PubMed)
    Show all 5 references for 181989

  2. Human Monoclonal Notch1 Primary Antibody for CyTOF, FACS - ABIN256488 : Ray, Yao, Nowotny, Mumm, Zhang, Wu, Kopan, Goate: Evidence for a physical interaction between presenilin and Notch. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 5 references for 256488

  3. Human Polyclonal Notch1 Primary Antibody for FACS, ICC - ABIN4899863 : Brosh, Hrynyk, Shen, Waghray, Zheng, Lemischka: A dual molecular analogue tuner for dissecting protein function in mammalian cells. in Nature communications 2016 (PubMed)

  4. Human Monoclonal Notch1 Primary Antibody for ELISA (Capture), FACS - ABIN4899411 : Le Friec, Sheppard, Whiteman, Karsten, Shamoun, Laing, Bugeon, Dallman, Melchionna, Chillakuri, Smith, Drouet, Couzi, Fremeaux-Bacchi, Köhl, Waddington, McDonnell, Baker, Handford, Lea, Kemper: The CD46-Jagged1 interaction is critical for human TH1 immunity. in Nature immunology 2012 (PubMed)

  5. Human Monoclonal Notch1 Primary Antibody for FACS - ABIN4896080 : Piggott, Deng, Warrington, Younge, Kubo, Desai, Goronzy, Weyand: Blocking the NOTCH pathway inhibits vascular inflammation in large-vessel vasculitis. in Circulation 2011 (PubMed)

  6. Human Monoclonal Notch1 Primary Antibody for IF, RPPA - ABIN2452671 : Harada, Sato, Ikeda, Hsu, Igarashi, Nakanuma: Notch1-Hes1 signalling axis in the tumourigenesis of biliary neuroendocrine tumours. in Journal of clinical pathology 2013 (PubMed)

  7. Cow (Bovine) Polyclonal Notch1 Primary Antibody for WB - ABIN2781033 : Sahlgren, Gustafsson, Jin, Poellinger, Lendahl: Notch signaling mediates hypoxia-induced tumor cell migration and invasion. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

更多抗Notch1的相互作用对抗体

Human Notch 1 (NOTCH1) interaction partners

  1. In conclusion, Notch siganling appears to be an important mediator of the liver inflammation by modulating hepatic IL-22 (显示 IL22 抗体)-secreting NKp46 (显示 NCR1 抗体)(+) innate lymphoid cells.

  2. High Notch1 expression is associated with basal-like breast cancer.

  3. High NOTCH1 expression is associated with T-cell leukemia.

  4. this is the first report of a NOTCH1 mutation associated with familial cases of a single ventricle defect

  5. High NOTCH1 expression is associated with ovarian cancer.

  6. These data suggest that a key pathomechanism for this novel form of muscular dystrophy with POGLUT1 (显示 POGLUT1 抗体) mutation is Notch-dependent loss of satellite cells.

  7. Genes that were dysregulated due to NOTCH1 haploinsufficiency in mice with shortened telomeres were concordant with proosteoblast and proinflammatory gene network alterations

  8. The PROX1 (显示 PROX1 抗体)/KLF2 (显示 KLF2 抗体) complex upregulates the expression of DTX1 (显示 DTX1 抗体) and DTX3L (显示 DTX3L 抗体). DTX1 (显示 DTX1 抗体) and DTX3L (显示 DTX3L 抗体), functioning as a heterodimeric Notch E3 ligase, concertedly downregulate NOTCH1 activity and enhance lymphatic sprouting

  9. Taken together, our data demonstrate that JNK (显示 MAPK8 抗体) regulates triple-negative breast cancer (TNBC)tumorigenesis by promoting CSC phenotype through Notch1 signaling via activation of c-Jun (显示 JUN 抗体) and indicate that JNK/c-Jun/Notch1 signaling is a potential therapeutic target for TNBC

  10. Studied the correlation between histone acetylation and Notch1 expression in lung carcinoma; results show a significant correlation between the level of acetylation of histone H3 (显示 HIST3H3 抗体) surrounding the promoter region of Notch1, and expression of Notch1 in human lung cancer cell lines.

Mouse (Murine) Notch 1 (NOTCH1) interaction partners

  1. Dll4 (显示 DLL4 抗体)-Notch1 signalling couples sprouting angiogenesis and artery formation.

  2. Genes that were dysregulated due to NOTCH1 haploinsufficiency in mice with shortened telomeres were concordant with proosteoblast and proinflammatory gene network alterations

  3. this study shows that Notch signaling regulates basophils biological function, at least partially via the modulation of MAPK (显示 MAPK1 抗体)

  4. The PROX1 (显示 C16orf35 抗体)/KLF2 (显示 KLF2 抗体) complex upregulates the expression of DTX1 (显示 DTX1 抗体) and DTX3L (显示 DTX3L 抗体). DTX1 (显示 DTX1 抗体) and DTX3L (显示 DTX3L 抗体), functioning as a heterodimeric Notch E3 ligase, concertedly downregulate NOTCH1 activity and enhance lymphatic sprouting

  5. Postnatal development analysis revealed that in cilia-deficient corneal epithelial cells downregulation of the Notch pathway precedes cell proliferation defects.

  6. a2V deficiency disrupts the endolysosomal route in Notch and TGF signaling, thereby impairing mammary gland development.

  7. ACTG2 (显示 ACTG2 抗体) boosts the metastatic potential of hepatocellular carcinoma in a Notch1-dependent manner.

  8. The results have unraveled a novel molecular pathway driven by interactions between prion protein (PrP (显示 PRNP 抗体)) and Notch1 in the progression of pancreatic ductal adenocarcinoma (PDAC), supporting a critical tumor-promoting role of Notch1 in PrP-expressing PDAC tumors.

  9. these results show that ADAM10 (显示 ADAM10 抗体)-Notch signaling in ovarian somatic cells governs the primordial follicle formation by controlling the development of ovarian pregranulosa cells.

  10. Notch1 and Notch2 (显示 NOTCH2 抗体) are the primary Notch receptors regulating epithelial cell homoeostasis in mouse and human stomach.

Xenopus laevis Notch 1 (NOTCH1) interaction partners

  1. Notch initially destabilises beta-catenin (显示 CTNNB1 抗体) in a process that does not depend on its phosphorylation by GSK3 (显示 GSK3b 抗体)

  2. Notch signaling promotes floor plate and hypochord fates over notochord, but has variable effects on Shh (显示 SHH 抗体) expression in the midline.

  3. Transgenic tadpoles were prepared with an elastase promoter driving either the stromelysin-3 (显示 MMP11 抗体) gene or the constitutively active form of Notch (IC).

  4. ZFP423 (显示 104125 抗体) coordinates Notch1 and bone morphogenetic protein signaling, selectively up-regulating Hes5 (显示 HES5 抗体) gene expression.

  5. results suggest that a cell-to-cell interaction via the Notch/Su(H (显示 RBPJ 抗体)) pathway has a significant role in the PGC (显示 PGC 抗体) migration by regulating cell motility

  6. the process of delimiting the three germ layers requires Notch signaling.

  7. BCL6 (显示 BCL6 抗体) inhibits transcription by competing for the Notch1 intracellular domain, preventing the coactivator Mastermind-like1 (MAM1 (显示 MAML1 抗体)) from binding.

  8. the combination of XSICD-mediated intracellular signaling and the extracellular domain of Notch ligands-mediated activation of Notch receptor is involved in the primary neurogenesis

  9. Notch signaling is activated when activin (显示 Actbeta 抗体)-like signaling induces various tissues from homogenous undifferentiated cells.

  10. Notch controls smad2 (显示 SMAD2 抗体) nuclear localization and the competence of ectodermal cells for activin A (显示 INHBA 抗体) in Xenopus embryos

Cow (Bovine) Notch 1 (NOTCH1) interaction partners

  1. the NOTCH1 polymorphism g.A48250G was significantly associated with body height, body weight, and height at hip cross, and that g.A49239C only showed significant associations with body height

  2. bovine herpesvirus 1 ORF2 protein reduced the trans-activation potential of Notch1 and Notch3 (显示 NOTCH3 抗体), suggesting that ORF2 interfered with the trans-activation potential of Notch.

  3. Cellular size or Notch1 expression is not per se a specific marker for mesenchymal progenitor cells in adult articular cartilage.

Notch1 (NOTCH1) 抗原简介

Antigen Summary

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.

Alternative names and synonyms associated with Notch1 (NOTCH1)

  • notch 1 (notch1) 抗体
  • notch 1 (NOTCH1) 抗体
  • Notch homolog 1, translocation-associated (Drosophila) (NOTCH1) 抗体
  • Notch homolog 1, translocation-associated (NOTCH1) 抗体
  • notch 1 (Notch1) 抗体
  • 9930111A19Rik 抗体
  • hN1 抗体
  • lin-12 抗体
  • Mis6 抗体
  • N1 抗体
  • NOTCH 抗体
  • notch-1 抗体
  • NOTCH1 抗体
  • notch1-a 抗体
  • Tan1 抗体
  • xnotch 抗体
  • xnotch1 抗体
  • Xotch 抗体

Protein level used designations for anti-Notch 1 (NOTCH1) 抗体

notch 1 , Notch homolog 1, translocation-associated (Drosophila) , Notch homolog 1, translocation-associated , neurogenic locus notch homolog protein 1 , translocation-associated notch protein TAN-1 , Motch A , Notch gene homolog 1 , mT14 , major type A protein , p300 , transmembrane receptor Notch1 , Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila) , neurogenic locus notch protein homolog , NOTCH-1

GENE ID SPECIES
100190917 Oncorhynchus mykiss
100631526 Amphimedon queenslandica
720888 Macaca mulatta
100037842 Xenopus (Silurana) tropicalis
100068764 Equus caballus
100144593 Sus scrofa
100224074 Taeniopygia guttata
4851 Homo sapiens
18128 Mus musculus
25496 Rattus norvegicus
394367 Xenopus laevis
395655 Gallus gallus
464865 Pan troglodytes
480676 Canis lupus familiaris
767866 Bos taurus
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