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FBXW7 蛋白

(F-Box and WD Repeat Domain Containing 7 (FBXW7))

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class\; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012].

recommended

FBXW7 Protein (AA 599-707) (GST tag) (ABIN1353879)

FBXW7 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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recommended

FBXW7 Protein (AA 1-553) (GST tag) (ABIN1990130)

FBXW7 宿主: 人宿主: 小麦胚 Recombinant ELISA, WB, AA, AP

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recommended

FBXW7 Protein (AA 1-707) (Strep Tag) (ABIN3092548)

Crystallography grade FBXW7 宿主: 人宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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FBXW7 蛋白 by Grade

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FBXW7 蛋白 by Origin

Find FBXW7 蛋白 for a variety of species such as anti-Human FBXW7, anti-Mouse FBXW7. The species listed below are among those available. Click on a link to go to the corresponding products.

FBXW7 蛋白 by Source

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FBXW7 蛋白 by 蛋白类型

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FBXW7 蛋白 by 应用范围

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Popular FBXW7 蛋白

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

FBXW7 Protein (AA 599-707) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1353879

Quantity 10 μg

Datasheet Datasheet

FBXW7 Protein (AA 1-553) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1990130

Quantity 25 μg

Datasheet Datasheet

FBXW7 Protein (AA 1-707) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3092548

Quantity 1 mg

Datasheet Datasheet

FBXW7 Protein (AA 1-629) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3136692

Quantity 1 mg

Datasheet Datasheet

Aliases for FBXW7 蛋白

F-box and WD repeat domain containing 7 (Fbxw7) 蛋白
F-box and WD repeat domain containing 7 (FBXW7) 蛋白
F-box and WD repeat domain containing 7 (fbxw7) 蛋白
F-box and WD-40 domain protein 7 (Fbxw7) 蛋白
1110001A17Rik 蛋白
AGO 蛋白
cdc4 蛋白
CDC4 蛋白
Cdc4 蛋白
FBW6 蛋白
FBW7 蛋白
Fbw7 蛋白
Fbwd6 蛋白
FBX30 蛋白
Fbx30 蛋白
FBXO30 蛋白
Fbxo30 蛋白
FBXW6 蛋白
Fbxw6 蛋白
hAgo 蛋白
hCdc4 蛋白
SEL-10 蛋白
SEL10 蛋白

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FBXW7 蛋白 by Grade

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FBXW7 蛋白 by 应用范围

Popular FBXW7 蛋白

Aliases for FBXW7 蛋白

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