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anti-ADAM17 (ADAM17) 抗体产品概述

Full name:
anti-ADAM Metallopeptidase Domain 17 抗体 (ADAM17)
在www.antibodies-online.cn可供255 ADAM Metallopeptidase Domain 17 (ADAM17) 抗体的32不同的供货商。 再加上,我们可以发ADAM17 试剂盒 (32)ADAM17 蛋白 (15)和数多这个蛋白质的别的产品。 总共310 ADAM17产品已列进来了。
adam17, ADAM18, CD156B, CSVP, NISBD, si:dkey-81b15.2, Tace

最受欢迎的抗anti-ADAM17 (ADAM17) 抗体


抗Mouse (Murine) ADAM17 抗体:

抗Human ADAM17 抗体:

抗Rat (Rattus) ADAM17 抗体:

所有可销售的anti-ADAM17 抗体


引用最多的anti-ADAM17 抗体

  1. Human Polyclonal ADAM17 Primary Antibody for EIA, IF - ABIN500861 : Giegel, Chaplin: Targets in cytokine activation. in Agents and actions. Supplements 1998 (PubMed)
    Show all 6 references for ABIN500861

  2. Human Polyclonal ADAM17 Primary Antibody for WB - ABIN264994 : Black, Rauch, Kozlosky, Peschon, Slack, Wolfson, Castner, Stocking, Reddy, Srinivasan, Nelson, Boiani, Schooley, Gerhart, Davis, Fitzner, Johnson, Paxton, March, Cerretti: A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. in Nature 1997 (PubMed)
    Show all 6 references for ABIN264994

  3. Human Polyclonal ADAM17 Primary Antibody for ELISA, WB - ABIN1531481 : Bilousova, Taylor, Emirzian, Gylys, Frautschy, Cole, Teng: Parallel age-associated changes in brain and plasma neuronal pentraxin receptor levels in a transgenic APP/PS1 rat model of Alzheimer's disease. in Neurobiology of disease 2015 (PubMed)
    Show all 3 references for ABIN1531481

  4. Human Polyclonal ADAM17 Primary Antibody for ELISA, WB - ABIN1536098 : Moss, Jin, Milla, Bickett, Burkhart, Carter, Chen, Clay, Didsbury, Hassler, Hoffman, Kost, Lambert, Leesnitzer, McCauley, McGeehan, Mitchell, Moyer, Pahel, Rocque, Overton, Schoenen, Seaton, Su et al.: Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha. ... in Nature 1997 (PubMed)
    Show all 2 references for ABIN1536098

  5. Human Polyclonal ADAM17 Primary Antibody for FACS, WB - ABIN388309 : Tellier, Canault, Poggi, Bonardo, Nicolay, Alessi, Nalbone, Peiretti: HDLs activate ADAM17-dependent shedding. in Journal of cellular physiology 2007 (PubMed)
    Show all 2 references for ABIN388309

  6. Human Polyclonal ADAM17 Primary Antibody for EIA, WB - ABIN357025 : Takamune, Ikebe, Nagano, Shinohara: Involvement of NF-kappaB-mediated maturation of ADAM-17 in the invasion of oral squamous cell carcinoma. in Biochemical and biophysical research communications 2007 (PubMed)
    Show all 2 references for ABIN357025


Mouse (Murine) ADAM Metallopeptidase Domain 17 (ADAM17) interaction partners

  1. Matrix metalloproteases ADAM10 and TACE (ADAM17) cleave AXL receptor tyrosine (显示 AXL 抗体)kinase (Axl) in lupus-prone leukocytes.

  2. These findings suggest that maintaining ADAM17-EGFR (显示 EGFR 抗体) epithelial signaling is necessary for the recovery from UC and would be beneficial to therapeutic strategies targeting ADAM17-mediated TNF-a (显示 TNF 抗体) shedding.

  3. Data show that caveolin 1 (CAV1 (显示 CAV1 抗体)) is required for transforming growth factor-beta (TGF-beta)-induced reactive oxygen species production, mediated by NADPH oxidase (显示 NOX1 抗体) NOX1 (显示 NOX1 抗体), that is necessary for a disintegrin and metalloproteinase 17 (ADAM17) activation.

  4. ADAM12 (显示 ADAM12 抗体) and ADAM17 are essential molecules for the impairment of barrier function of retinal vasculature under hypoxia.

  5. 4-Hydroxyisoleucine improved insulin (显示 INS 抗体) resistant-like state in 3T3-L1 adipocytes by targeting TACE/TIMP3 (显示 TIMP3 抗体) and the insulin (显示 INS 抗体) signaling pathway.

  6. Hypercapnic acidosis blocks stretch-mediated activation of ADAM17. ADAM17 is an important proximal mediator of ventilator-induced lung injury.

  7. Lrig2 has a role in negative regulation of ectodomain shedding of axon guidance receptors by ADAM17 protease

  8. Overexpression of ADAM17 increases shed ACE2 (显示 ACE2 抗体) and decreases cellular ACE2 (显示 ACE2 抗体) levels in pancreatic islets. Whereas ADAM17 has the ability to shed ACE2 (显示 ACE2 抗体), ADAM17 does not deplete ACE2 (显示 ACE2 抗体) from pancreatic islets in diabetic db/db (显示 LEPR 抗体) mice.

  9. established that endogenous IL-6R of both human and murine origin is shed by ADAM17 in an induced manner, whereas constitutive release of endogenous IL-6R is largely mediated by ADAM10 (显示 ADAM10 抗体)

  10. These data demonstrated that ADAM17 contributed to microglial cell survival, predominantly by EGFR (显示 EGFR 抗体) signalling, following spinal cord injury

Human ADAM Metallopeptidase Domain 17 (ADAM17) interaction partners

  1. Our data demonstrated that elevated serum Semaphorin5A (Sema5A (显示 SEMA5A 抗体)) in SLE patients correlated with disease activity and are involved in kidney and blood system damage; ADAM17 might be involved in the release of secreted Sema5A (显示 SEMA5A 抗体).

  2. ADAM17 and ADAM10 (显示 ADAM10 抗体) cleave Nectin-4 (显示 PVRL4 抗体) and release soluble Nectin-4 (显示 PVRL4 抗体) (sN4).

  3. ADAM17 promotes epithelial-mesenchymal transition via the TGF-beta (显示 TGFB1 抗体)/Smad (显示 SMAD1 抗体) pathway. the present study demonstrates that ADAM17 plays a critical role in the development of gastric cancer and provides a potential therapeutic target for gastric cancer.

  4. FHL2 (显示 FHL2 抗体) interacts with ADAM-17 in normal, dysplastic and malignant colon epithelial cells. Colocalisation of these proteins is more frequent in malignant than in normal and dysplastic cells, suggesting a role for ADAM-17/FHL2 (显示 FHL2 抗体) complex in the development of colorectal cancer.

  5. The present study suggests that ADAM17-siRNA inhibits MCF-7 breast cancer and is activated through the EGFR (显示 EGFR 抗体)-PI3K (显示 PIK3CA 抗体)-AKT (显示 AKT1 抗体) signaling pathway

  6. Data show that mononuclear leukocytes (PBMC) AXL receptor tyrosine kinase (Axl (显示 AXL 抗体)) is rescued by combined matrix metalloproteases ADAM10 (显示 ADAM10 抗体) and TACE (ADAM17) inhibition.

  7. the TLR4 (显示 TLR4 抗体)/Gal-1 (显示 LGALS1 抗体) signaling pathway regulates lactate-mediated EMT (显示 ITK 抗体) processes through the activation of ADAM10 (显示 ADAM10 抗体) and ADAM17 in colon cancer cells.

  8. The HNE-TACE signalling pathway has an important role in the process of MUC5AC overexpression in chronic rhinosinusitis.

  9. The inhibition of cell proliferation and invasion was observed in the ADAM17 knockdown cells, which was associated with modulation of the EGFR (显示 EGFR 抗体) signalling pathway.

  10. ADAM17 expression was increased in the sepsis patients with the rs12692386 GA/GG genotypes, accompanied by up-regulation of expression of the ADAM17 substrates (TNF-alpha (显示 TNF 抗体), IL-6R and CX3CL1 (显示 CX3CL1 抗体)) and pro-inflammatory cytokines (IL-1beta (显示 IL1B 抗体) and IL-6 (显示 IL6 抗体)).

Pig (Porcine) ADAM Metallopeptidase Domain 17 (ADAM17) interaction partners

  1. ADAM17 was involved in porcine CD16 (显示 CD16 抗体) shedding in porcine reproductive and respiratory syndrome virus-infected pigs.

  2. Overexpression of ADAM17 induced downregulation of CD163 (显示 CD163 抗体) expression and a reduction in reproductive and respiratory syndrome virus infection.

  3. activation of TACE/ADAM17 via a PKC (显示 FYN 抗体)-induced c-Src (显示 SRC 抗体)-dependent manner mediates proteolytic activation of the EGF (显示 EGF 抗体)-like factors that are involved in the induction of granulosa cell differentiation, cumulus expansion, and meiotic maturation of porcine oocytes

  4. Data indicate that TNF-alpha (显示 TNF 抗体) stimulates Rac (显示 AKT1 抗体), ADAM17/TACE, and RhoA (显示 RHOA 抗体) through the guanine nucleotide exchange factor (显示 ARHGEF12 抗体) (GEF)-H1 (显示 ARHGEF2 抗体).

  5. progesterone-induced TACE/ADAM17 leads to production of soluble EGF (显示 EGF 抗体) domain from cumulus cells, which enhances functional changes of cumulus cells and progresses meiotic maturation of oocytes

ADAM17 抗原简介

Antigen Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme\; binds mitotic arrest deficient 2 protein\; and also plays a prominent role in the activation of the Notch signaling pathway.

Alternative names and synonyms associated with ADAM17

  • ADAM metallopeptidase domain 17 (ADAM17) 抗体
  • a disintegrin and metallopeptidase domain 17b (adam17b) 抗体
  • ADAM metallopeptidase domain 17 (adam17) 抗体
  • a disintegrin and metallopeptidase domain 17 (Adam17) 抗体
  • ADAM metallopeptidase domain 17 (Adam17) 抗体
  • adam17 抗体
  • ADAM18 抗体
  • CD156B 抗体
  • CSVP 抗体
  • NISBD 抗体
  • si:dkey-81b15.2 抗体
  • Tace 抗体

Protein level used designations for ADAM17

ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme) , a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) , disintegrin and metalloproteinase domain-containing protein 17 , tumor necrosis factor alpha converting enzyme , a disintegrin and metallopeptidase domain 17 , ADAM metallopeptidase domain 17 , a disintegrin and metalloprotease domain 17 , disintegrin metalloproteinase , disintegrin and metalloproteinase domain-containing protein 17-like , ADAM 17 , TNF-alpha convertase , TNF-alpha converting enzyme , TNF-alpha-converting enzyme , a disintegrin and metalloprotease domain 17; TNF-alpha converting enzyme , a disintegrin and metalloproteinase domain 17 , ADAM metallopeptidase domain 18 , snake venom-like protease , tumor necrosis factor, alpha, converting enzyme

421931 Gallus gallus
459018 Pan troglodytes
560657 Danio rerio
694429 Macaca mulatta
733430 Xenopus laevis
100072496 Equus caballus
100406520 Callithrix jacchus
100482770 Ailuropoda melanoleuca
11491 Mus musculus
6868 Homo sapiens
57027 Rattus norvegicus
475662 Canis lupus familiaris
397343 Sus scrofa
517541 Bos taurus
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