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anti-ADAM10 (ADAM10) 抗体产品概述

Full name:
anti-ADAM Metallopeptidase Domain 10 抗体 (ADAM10)
在www.antibodies-online.cn可供137 ADAM Metallopeptidase Domain 10 (ADAM10) 抗体的29不同的供货商。 再加上,我们可以发ADAM10 试剂盒 (43)ADAM10 蛋白 (21)和数多这个蛋白质的别的产品。 总共205 ADAM10产品已列进来了。
别名:
1700031C13Rik, ad10, ADAM-10, ADAM 10, Adam10, cd156c, HsT18717, kuz, kuzbanian, LOC100219653, madm, wu:fc03d12, xadam10
列出全部抗体 基因 基因ID UniProt
ADAM10 11487 O35598
ADAM10 102 O14672
ADAM10 29650  

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引用最多的anti-ADAM10 抗体

  1. Human Polyclonal ADAM10 Primary Antibody for WB - ABIN264988 : Rosendahl, Ko, Long, Brewer, Rosenzweig, Hedl, Anderson, Pyle, Moreland, Meyers, Kohno, Lyons, Lichenstein: Identification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases. in The Journal of biological chemistry 1997 (PubMed)
    Show all 4 references for ABIN264988

  2. Mouse (Murine) Monoclonal ADAM10 Primary Antibody for FACS - ABIN4897869 : Doi, Imai, Kressler, Yagita, Agata, Vooijs, Hamazaki, Inoue, Minato: Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia. in Scientific reports 2015 (PubMed)
    Show all 4 references for ABIN4897869

  3. Human Polyclonal ADAM10 Primary Antibody for EIA, IF - ABIN499211 : Pan, Rubin: Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis. in Cell 1997 (PubMed)
    Show all 4 references for ABIN499211

  4. Cow (Bovine) Polyclonal ADAM10 Primary Antibody for EIA, IF - ABIN401037 : Qi, Rand, Wu, Sestan, Wang, Rakic, Xu, Artavanis-Tsakonas: Processing of the notch ligand delta by the metalloprotease Kuzbanian. in Science (New York, N.Y.) 1999 (PubMed)
    Show all 4 references for ABIN401037

  5. Mouse (Murine) Monoclonal ADAM10 Primary Antibody for FACS - ABIN4897868 : Gibb, Saleem, Kang, Subler, Conrad: ADAM10 overexpression shifts lympho- and myelopoiesis by dysregulating site 2/site 3 cleavage products of Notch. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Show all 2 references for ABIN4897868

  6. Human Monoclonal ADAM10 Primary Antibody for FACS - ABIN4897866 : Nygaard, Pallister, Zurek, Voyich: The impact of α-toxin on host cell plasma membrane permeability and cytokine expression during human blood infection by CA-MRSA USA300. in Journal of leukocyte biology 2013 (PubMed)

  7. Human Polyclonal ADAM10 Primary Antibody for IF (p), IHC (p) - ABIN701020 : Li, Xie, He, Wang, Duan, Yang, Wang: Identification of ADAM10 and ADAM17 with potential roles in the spermatogenesis of the Chinese mitten crab, Eriocheir sinensis. in Gene 2015 (PubMed)

更多抗ADAM10的相互作用对抗体

Mouse (Murine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Newborn mice deficient in ADAM10 exhibited organ-specific vascular defects.

  2. Findings demonstrate the direct requirement of ADAM10 in cortical radial migration and reveal the underlying mechanism by linking ADAM10-initiated regulated intramembrane proteolysis of Notch (显示 NOTCH1 抗体) to the regulation of microtubule cytoskeleton through transcriptional control of Dcx (显示 DCX 抗体) expression

  3. our data afford the new insight that miR (显示 MLXIP 抗体)-103a inhibited abdominal aortic aneurysm (AAA (显示 AAAS 抗体)) growth via targeting ADAM10, which might be a promising therapeutic strategy to alleviate AAA (显示 AAAS 抗体).

  4. ADAM10 gene was predominantly expressed in the neurons of the cerebral cortex, hippocampus, thalamus and cerebellar granular cells in adult mouse CNS.

  5. Matrix metalloproteases ADAM10 and TACE (ADAM17) cleave AXL receptor tyrosine (显示 AXL 抗体)kinase (Axl) in lupus-prone leukocytes.

  6. Loss of ADAM10 in murine liver results in hepatocyte necrosis and concomitant liver fibrosis. ADAM10 directly regulates expression of bile acid transporters but is dispensable for Notch2 (显示 NOTCH2 抗体)-dependent formation of the biliary system. Differentiation of liver progenitor cells to hepatocytes is augmented in the absence of ADAM10.

  7. Studies demonstrate a role for ADAM10 in the ectodomain shedding of LRP1 (显示 LRP1 抗体) in the brain and the clearance of Abeta (显示 APP 抗体) across the blood-brain barrier, which may provide a novel strategy for attenuating Abeta (显示 APP 抗体) accumulation in the AD brain

  8. With a proteomic analysis of Adam10-deficient neurons the authors identified 91, mostly novel ADAM10 substrate candidates, making ADAM10 a major protease for membrane proteins in the nervous system.

  9. Data suggest that large extracellular loop of Tspan14 mediates interaction with ADAM10, promotes ADAM10 maturation/trafficking to cell surface, and affects ADAM10 substrate specificity; ADAM10/Tspan14 interact in platelets/vascular endothelial cells.

  10. findings underscore the role of ADAM10 as an indispensable component of Notch (显示 NOTCH1 抗体) signaling in SCs (显示 TWIST1 抗体) and for maintaining the SC pool

Human ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. ADAM17 (显示 ADAM17 抗体) and ADAM10 cleave Nectin-4 (显示 PVRL4 抗体) and release soluble Nectin-4 (显示 PVRL4 抗体) (sN4).

  2. Data show that mononuclear leukocytes (PBMC) AXL receptor tyrosine kinase (Axl (显示 AXL 抗体)) is rescued by combined matrix metalloproteases ADAM10 and TACE (ADAM17 (显示 ADAM17 抗体)) inhibition.

  3. we found that ADAM10 expression was associated with a more rapid metastatic progression confirming its role in uveal melanoma metastasis.

  4. the TLR4 (显示 TLR4 抗体)/Gal-1 (显示 LGALS1 抗体) signaling pathway regulates lactate-mediated EMT (显示 ITK 抗体) processes through the activation of ADAM10 and ADAM17 (显示 ADAM17 抗体) in colon cancer cells.

  5. Studies demonstrate a role for ADAM10 in the ectodomain shedding of LRP1 (显示 LRP1 抗体) in the brain and the clearance of Abeta (显示 APP 抗体) across the blood-brain barrier, which may provide a novel strategy for attenuating Abeta (显示 APP 抗体) accumulation in the AD brain

  6. In response to trastuzumab, both HER3 (显示 ERBB3 抗体) and the metalloprotease (显示 ADAM8 抗体) ADAM10 are simultaneously upregulated. The proteolytic activity of the latter then releases the HER3 (显示 ERBB3 抗体) ligand heregulin (显示 NRG1 抗体) from the cell surface to activate HER3 (显示 ERBB3 抗体) and confer resistance to trastuzumab by inducing compensatory growth factor receptor (显示 RYK 抗体) signaling.

  7. Active ADAM10 promotes the carcinogenesis, invasion, metastasis and proliferation of ESCC and controls invasion and metastasis at least in part through the shedding of E-cadherin (显示 CDH1 抗体) activity.

  8. We now show that ADAM10 is critical for alpha-hemolysin (显示 PLC 抗体)-mediated activation of the NLRP3 (显示 NLRP3 抗体) inflammasome in human monocytes as siRNA knockdown or chemical blockade of ADAM10-alpha-hemolysin (显示 PLC 抗体) interaction leads to diminished inflammasome activation and cell death by reducing the available ADAM10 on the cell surface.

  9. ADAM10 was overexpressed in the posterior band of sections from some patients with temporomandibular joint disk disorders.

  10. ADAM10 activity contributes to house dust mite-induced shedding of chemokines, including CCL20 (显示 CCL20 抗体)

Xenopus laevis ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. A dramatic decline in ephrinB2 (显示 EFNB2 抗体) protein levels on the absence of flotillin-1 (显示 FLOT1 抗体) expression is specific, and is partly the result of an increased susceptibility to cleavage by the metalloprotease (显示 ADAM8 抗体) ADAM10.

Pig (Porcine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. significantly increased expression of ADAM10 in the ISR versus non-ISR segment in diabetic minipigs

Cow (Bovine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Data show that ADAM10 and APLP2 (显示 APLP2 抗体) are expressed in proximal tubule cells, and that ADAM10 activity has a pronounced effect on expression of specific brush-border proteins.

  2. Intracellular trafficking of ADAM10 critically requires a novel sorting signal within its cytoplasmic domain.

  3. N-glycosylation is crucial for ADAM10 processing and resistance to proteolysis, and results suggest that it is required for full-enzyme activity.

ADAM10 抗原简介

Antigen Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.

Alternative names and synonyms associated with ADAM10

  • a disintegrin and metalloprotease domain 10a (adam10a) 抗体
  • ADAM metallopeptidase domain 10 (ADAM10) 抗体
  • ADAM metallopeptidase domain 10 (LOC100219653) 抗体
  • ADAM metallopeptidase domain 10 (Adam10) 抗体
  • a disintegrin and metallopeptidase domain 10 (Adam10) 抗体
  • ADAM metallopeptidase domain 10 (adam10) 抗体
  • ADAM10 (LOC100101614) 抗体
  • 1700031C13Rik 抗体
  • ad10 抗体
  • ADAM-10 抗体
  • ADAM 10 抗体
  • Adam10 抗体
  • cd156c 抗体
  • HsT18717 抗体
  • kuz 抗体
  • kuzbanian 抗体
  • LOC100219653 抗体
  • madm 抗体
  • wu:fc03d12 抗体
  • xadam10 抗体

Protein level used designations for ADAM10

a disintegrin and metalloprotease domain 10a , ADAM metallopeptidase domain 10 , disintegrin and metalloproteinase domain-containing protein 10 , ADAM10 metallopeptidase , disintegrin and metalloproteinase domain-containing protein 10-like , ADAM 10 , a disintegrin and metalloprotease domain (ADAM) 10 , a disintegrin and metalloprotease domain 10 , kuzbanian protein homolog , mammalian disintegrin-metalloprotease , CDw156 , a disintegrin and metalloproteinase domain 10 , metalloprotease/disintegrin , xKuz , a disintegrin and metallopeptidase domain 10 , disintegrin-metalloproteinase , myelin-associated metalloproteinase

GENE ID SPECIES
566044 Danio rerio
701355 Macaca mulatta
746942 Pan troglodytes
100068314 Equus caballus
100169741 Pongo abelii
100219653 Taeniopygia guttata
100313545 Saccoglossus kowalevskii
100476350 Ailuropoda melanoleuca
100606667 Nomascus leucogenys
11487 Mus musculus
102 Homo sapiens
399187 Xenopus laevis
29650 Rattus norvegicus
374113 Gallus gallus
478321 Canis lupus familiaris
397345 Sus scrofa
282132 Bos taurus
100718999 Cavia porcellus
100101614 Oryctolagus cuniculus
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