anti-ADAM10 (ADAM10) 抗体产品概述

Full name:
anti-ADAM Metallopeptidase Domain 10 抗体 (ADAM10)
在www.antibodies-online.cn可供168 ADAM Metallopeptidase Domain 10 (ADAM10) 抗体的30不同的供货商。 再加上,我们可以发ADAM10 试剂盒 (44)ADAM10 蛋白 (21)和数多这个蛋白质的别的产品。 总共237 ADAM10产品已列进来了。
别名:
1700031C13Rik, ad10, ADAM-10, ADAM 10, Adam10, cd156c, HsT18717, kuz, kuzbanian, LOC100219653, madm, wu:fc03d12, xadam10
列出全部抗体 基因 基因ID UniProt
ADAM10 11487 O35598
ADAM10 102 O14672
ADAM10 29650  

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  1. Human Monoclonal ADAM10 Primary Antibody for FACS, IP - ABIN4900520 : Zingoni, Cecere, Vulpis, Fionda, Molfetta, Soriani, Petrucci, Ricciardi, Fuerst, Amendola, Mytilineos, Cerboni, Paolini, Cippitelli, Santoni: Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 5 references for 4900520

  2. Human Polyclonal ADAM10 Primary Antibody for WB - ABIN264988 : Rosendahl, Ko, Long, Brewer, Rosenzweig, Hedl, Anderson, Pyle, Moreland, Meyers, Kohno, Lyons, Lichenstein: Identification and characterization of a pro-tumor necrosis factor-alpha-processing enzyme from the ADAM family of zinc metalloproteases. in The Journal of biological chemistry 1997 (PubMed)
    Show all 4 references for 264988

  3. Cow (Bovine) Polyclonal ADAM10 Primary Antibody for EIA, IF - ABIN401037 : Pan, Rubin: Kuzbanian controls proteolytic processing of Notch and mediates lateral inhibition during Drosophila and vertebrate neurogenesis. in Cell 1997 (PubMed)
    Show all 4 references for 401037

  4. Mouse (Murine) Monoclonal ADAM10 Primary Antibody for FACS - ABIN4897869 : Doi, Imai, Kressler, Yagita, Agata, Vooijs, Hamazaki, Inoue, Minato: Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia. in Scientific reports 2015 (PubMed)
    Show all 4 references for 4897869

  5. Mouse (Murine) Monoclonal ADAM10 Primary Antibody for FACS - ABIN4897868 : Gibb, Saleem, Kang, Subler, Conrad: ADAM10 overexpression shifts lympho- and myelopoiesis by dysregulating site 2/site 3 cleavage products of Notch. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Show all 2 references for 4897868

  6. Human Monoclonal ADAM10 Primary Antibody for FACS - ABIN4897866 : Nygaard, Pallister, Zurek, Voyich: The impact of α-toxin on host cell plasma membrane permeability and cytokine expression during human blood infection by CA-MRSA USA300. in Journal of leukocyte biology 2013 (PubMed)

  7. Human Polyclonal ADAM10 Primary Antibody for IF (p), IHC (p) - ABIN701020 : Li, Xie, He, Wang, Duan, Yang, Wang: Identification of ADAM10 and ADAM17 with potential roles in the spermatogenesis of the Chinese mitten crab, Eriocheir sinensis. in Gene 2015 (PubMed)

更多抗ADAM10的相互作用对抗体

Mouse (Murine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. these results show that ADAM10-Notch (显示 NOTCH1 抗体) signaling in ovarian somatic cells governs the primordial follicle formation by controlling the development of ovarian pregranulosa cells.

  2. Findings provide evidence that ADAM10, and not ADAM17 (显示 ADAM17 抗体), is indispensable for proper retinal development as a regulator of NOTCH (显示 NOTCH1 抗体) signaling.

  3. this study shows that during positive selection in the spleen, B-cell receptor signaling causes immature type 1 transitional B cells to become receptive to Notch (显示 NOTCH1 抗体) ligands via Taok3 (显示 TAOK3 抗体)-mediated surface expression of ADAM10

  4. Thus, Leda-1/Pianp (显示 C12orf53 抗体) is constitutively processed by proprotein convertases, sheddases including MMPs and ADAM10/17 and intramembrane protease gamma-secretase.

  5. ADAM10 was dispensable for alpha-toxin (显示 PLC 抗体)-dependent xenophagic targeting of S. aureus, whereas a role for alpha-toxin (显示 PLC 抗体) attack on the plasma membrane was confirmed.

  6. ADAM10 was essentially involved in maxillofacial bone development. ADAM10 conditional knock-out KO mice present craniofacial dysmorphia and bone defects. Impaired osteoblast differentiation,proliferation and apoptosis underlie the bone deformity.

  7. Newborn mice deficient in ADAM10 exhibited organ-specific vascular defects.

  8. Findings demonstrate the direct requirement of ADAM10 in cortical radial migration and reveal the underlying mechanism by linking ADAM10-initiated regulated intramembrane proteolysis of Notch (显示 NOTCH1 抗体) to the regulation of microtubule cytoskeleton through transcriptional control of Dcx (显示 DCX 抗体) expression

  9. our data afford the new insight that miR (显示 MLXIP 抗体)-103a inhibited abdominal aortic aneurysm (AAA (显示 AAAS 抗体)) growth via targeting ADAM10, which might be a promising therapeutic strategy to alleviate AAA (显示 AAAS 抗体).

  10. ADAM10 gene was predominantly expressed in the neurons of the cerebral cortex, hippocampus, thalamus and cerebellar granular cells in adult mouse CNS.

Human ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Regulation of ADAM10 by the TspanC8 subgroup of tetraspanins, namely Tspan5 (显示 TSPAN5 抗体), 10, 14, 15, 17 and 33 is reviewed.

  2. active ADAM10 form marks cancer stem-like cells with active Notch (显示 NOTCH1 抗体) signaling, known to mediate chemoresistance.

  3. Data show that tetraspanin 33 (tspan33 (显示 TSPAN33 抗体)) is an early activation marker, and that disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) protein expression does not correlate with Tspan33 (显示 TSPAN33 抗体) expression in B cells.

  4. High ADAM10 expression is associated with metastasis of hepatocellular carcinoma.

  5. The dysregulation of ADAM10, Fas (显示 FAS 抗体) and FasL (显示 FASL 抗体) could be useful indicators of the progression and severity of OSCC.

  6. 1,25D3 causes ectodomain shedding of TLR4 (显示 TLR4 抗体) and thereby decreases the responsiveness of cells to LPS (显示 IRF6 抗体). ADAM10, activated by extracellular Ca2 (显示 CA2 抗体)+ influx, was implicated in the ectodomain cleavage of TLR4 (显示 TLR4 抗体).

  7. The overexpression of MTERF4 induced a significant increase in the levels of APP protein and secreted Abeta 42 in HEK293-APPswe cells compared with control cells these results suggest that MTERF4 promotes the amyloidogenic processing of APP by inhibiting ADAM10 in HEK293-APPswe cells; therefore, MTERF4 may play an important role in the pathogenesis of Alzheimer's disease.

  8. Pre-incubation with simvastatin prior to treatment with IL-1beta (显示 IL1B 抗体) + Oncostatin M (显示 OSM 抗体) decreased the level of CD44 (显示 CD44 抗体) fragmentation, decreased the proportion of CD44 (显示 CD44 抗体) that transits into the lipid raft fractions, decreased ADAM10 activity and diminished the interaction between CD44 (显示 CD44 抗体) and ADAM10.

  9. ADAM17 (显示 ADAM17 抗体) and ADAM10 cleave Nectin-4 (显示 PVRL4 抗体) and release soluble Nectin-4 (显示 PVRL4 抗体) (sN4).

  10. Data show that mononuclear leukocytes (PBMC) AXL receptor tyrosine kinase (Axl (显示 AXL 抗体)) is rescued by combined matrix metalloproteases ADAM10 and TACE (ADAM17 (显示 ADAM17 抗体)) inhibition.

Xenopus laevis ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. A dramatic decline in ephrinB2 (显示 EFNB2 PLURAL_@27060@) protein levels on the absence of flotillin-1 (显示 FLOT1 PLURAL_@27060@) expression is specific, and is partly the result of an increased susceptibility to cleavage by the metalloprotease (显示 ADAM8 PLURAL_@27060@) ADAM10.

Pig (Porcine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. significantly increased expression of ADAM10 in the ISR versus non-ISR segment in diabetic minipigs

Cow (Bovine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Data show that ADAM10 and APLP2 (显示 APLP2 抗体) are expressed in proximal tubule cells, and that ADAM10 activity has a pronounced effect on expression of specific brush-border proteins.

  2. Intracellular trafficking of ADAM10 critically requires a novel sorting signal within its cytoplasmic domain.

  3. N-glycosylation is crucial for ADAM10 processing and resistance to proteolysis, and results suggest that it is required for full-enzyme activity.

ADAM10 抗原简介

Antigen Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.

Alternative names and synonyms associated with ADAM10

  • a disintegrin and metalloprotease domain 10a (adam10a) 抗体
  • ADAM metallopeptidase domain 10 (ADAM10) 抗体
  • ADAM metallopeptidase domain 10 (LOC100219653) 抗体
  • ADAM metallopeptidase domain 10 (Adam10) 抗体
  • a disintegrin and metallopeptidase domain 10 (Adam10) 抗体
  • ADAM metallopeptidase domain 10 (adam10) 抗体
  • ADAM10 (LOC100101614) 抗体
  • 1700031C13Rik 抗体
  • ad10 抗体
  • ADAM-10 抗体
  • ADAM 10 抗体
  • Adam10 抗体
  • cd156c 抗体
  • HsT18717 抗体
  • kuz 抗体
  • kuzbanian 抗体
  • LOC100219653 抗体
  • madm 抗体
  • wu:fc03d12 抗体
  • xadam10 抗体

Protein level used designations for ADAM10

a disintegrin and metalloprotease domain 10a , ADAM metallopeptidase domain 10 , disintegrin and metalloproteinase domain-containing protein 10 , ADAM10 metallopeptidase , disintegrin and metalloproteinase domain-containing protein 10-like , ADAM 10 , a disintegrin and metalloprotease domain (ADAM) 10 , a disintegrin and metalloprotease domain 10 , kuzbanian protein homolog , mammalian disintegrin-metalloprotease , CDw156 , a disintegrin and metalloproteinase domain 10 , metalloprotease/disintegrin , xKuz , a disintegrin and metallopeptidase domain 10 , disintegrin-metalloproteinase , myelin-associated metalloproteinase

GENE ID SPECIES
566044 Danio rerio
701355 Macaca mulatta
746942 Pan troglodytes
100068314 Equus caballus
100169741 Pongo abelii
100219653 Taeniopygia guttata
100313545 Saccoglossus kowalevskii
100476350 Ailuropoda melanoleuca
100606667 Nomascus leucogenys
11487 Mus musculus
102 Homo sapiens
399187 Xenopus laevis
29650 Rattus norvegicus
374113 Gallus gallus
478321 Canis lupus familiaris
397345 Sus scrofa
282132 Bos taurus
100718999 Cavia porcellus
100101614 Oryctolagus cuniculus
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