anti-Tumor Necrosis Factor (TNF) 抗体产品概述

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anti-Tumor Necrosis Factor 抗体 (TNF)
在www.antibodies-online.cn可供1734 Tumor Necrosis Factor (TNF) 抗体的51不同的供货商。 再加上,我们可以发Tumor Necrosis Factor 试剂盒 (326)Tumor Necrosis Factor 蛋白 (270)和数多这个蛋白质的别的产品。 总共2367 Tumor Necrosis Factor产品已列进来了。
别名:
Cachectin, cTNF, DIF, RATTNF, tnf, TNF-a, Tnf-alpha, TNFa, tnfa-like, TNFalpha, Tnfsf1a, TNFSF2, xtnf
列出全部抗体 基因 基因ID UniProt
TNF 7124 P01375
TNF 21926 P06804
大鼠 TNF TNF 24835 P16599

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引用最多的anti-Tumor Necrosis Factor 抗体

  1. Human Polyclonal Tumor Necrosis Factor Primary Antibody for ICC, IF - ABIN446837 : Kwon, Jung, Hwang, Choi: Evaluation of Bronchiolar and Alveolar Cell Injuries Induced by Short- and Long-term Exposure to Sidestream Smoke. in Korean journal of pathology 2012 (PubMed)
    Show all 11 references for 446837

  2. Human Polyclonal Tumor Necrosis Factor Primary Antibody for IF (p), IHC (p) - ABIN677318 : Morishita, Oku, Horie, Tonari, Kida, Okubo, Sugiyama, Takai, Hara, Ikeda: Systemic simvastatin rescues retinal ganglion cells from optic nerve injury possibly through suppression of astroglial NF-?B activation. in PLoS ONE 2014 (PubMed)
    Show all 10 references for 677318

  3. Cow (Bovine) Monoclonal Tumor Necrosis Factor Primary Antibody for EIA, FACS - ABIN120182 : Hope, Whelan, Hewinson, Vordermeier, Howard: Maturation of bovine dendritic cells by lipopeptides. in Veterinary immunology and immunopathology 2003 (PubMed)
    Show all 4 references for 120182

  4. Human Polyclonal Tumor Necrosis Factor Primary Antibody for IF, IHC (p) - ABIN498271 : Chae, Park, Hwang, Kwon, Lim, Yi, Han, Kim, Baek: The effect of antioxidants on the production of pro-inflammatory cytokines and orthodontic tooth movement. in Molecules and cells 2011 (PubMed)
    Show all 2 references for 498271

  5. Human Monoclonal Tumor Necrosis Factor Primary Antibody for IF (p), IHC (p) - ABIN722481 : Zhang, Zha, Ye, Wang, Wang, Shen, Wu, Zhu: Complement C5a-C5aR interaction enhances MAPK signaling pathway activities to mediate renal injury in trichloroethylene sensitized BALB/c mice. in Journal of applied toxicology : JAT 2015 (PubMed)

  6. Baboon Monoclonal Tumor Necrosis Factor Primary Antibody for ELISA, FACS - ABIN263068 : Bimpis, Papalois, Voumvourakis, Oláh, Tiszlavicz, Liapi: Neuronal tumour necrosis factor-α and interleukin-1β expression in a porcine model of intracerebral haemorrhage: Modulation by U-74389G. in Brain research 2015 (PubMed)

  7. Human Monoclonal Tumor Necrosis Factor Primary Antibody for CC, ELISA - ABIN1997163 : Cohen, Sabhachandani, Golberg, Konry: Approaching near real-time biosensing: microfluidic microsphere based biosensor for real-time analyte detection. in Biosensors & bioelectronics 2014 (PubMed)

  8. Human Monoclonal Tumor Necrosis Factor Primary Antibody for FACS - ABIN1109411 : Arduise, Abache, Li, Billard, Chabanon, Ludwig, Mauduit, Boucheix, Rubinstein, Le Naour: Tetraspanins regulate ADAM10-mediated cleavage of TNF-alpha and epidermal growth factor. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

  9. Baboon Monoclonal Tumor Necrosis Factor Primary Antibody for ICC, FACS - ABIN263069 : Baker, Murphy, Lopez, Garcia: Conversion of a capture ELISA to a Luminex xMAP assay using a multiplex antibody screening method. in Journal of visualized experiments : JoVE 2012 (PubMed)

  10. Human Monoclonal Tumor Necrosis Factor Primary Antibody for EIA, FACS - ABIN118949 : Bebök, Márkus, Németh: Prognostic relevance of transforming growth factor alpha (TGF-alpha) and tumor necrosis factor alpha (TNF-alpha) detected in breast cancer tissues by immunohistochemistry. in Breast cancer research and treatment 1994 (PubMed)

更多抗Tumor Necrosis Factor的相互作用对抗体

Rainbow Trout (Oncorhynchus mykiss) Tumor Necrosis Factor (TNF) interaction partners

  1. Our findings demonstrate that TNF-alpha plays a pivotal role in HF-mediated neuroinflammation and associated alterations of cortical dendritic spine density and has the potential to reveal novel treatment strategies for HF-associated memory deficits.

  2. the present study assessed the combined impacts of estrogens and bacterial infection on the insulin (显示 INS 抗体)-like growth factors (IGF) and tumor-necrosis factor (TNF)-alpha.

  3. The expression of miR (显示 MYLIP 抗体)-125b-1 regulated by NF-kappaB (显示 NFKB1 抗体) has been reported in diverse cell types under various stimuli, this study found that its expression was also significantly regulated by NF-kappaB (显示 NFKB1 抗体) in TNFalpha-stimulated HeLa and HepG2 cells

  4. In the Han Chinese population, the allele 'A' of TNF-alpha -308 may increase the risk for osteoarthritis (OA), whereas TNF-alpha -238 polymorphisms do not play a role in OA patients.

  5. Letter: serum TNF-alpha was not elevated in chronic spontaneous urticaria.

  6. Metastatic cells can escape the proapoptotic effects of TNF-alpha through increased autocrine IL-6 (显示 IL6 抗体)/STAT3 (显示 STAT3 抗体) signaling

  7. The predicted 3D structures of IL-1beta (显示 IL1B 抗体), TNF-alpha, and IL-8 (显示 IL8 抗体) from Oncorhynchus mykiss, Dicentrarchus labrax, and Chionodraco hamatus are reported and the differences between them and their mammalian counterparts investigated.

  8. The mitochondrial dysfunction may be caused by increased brain levels of TNFalpha without physiological stress but will be exacerbated after middle cerebral artery occlusion.

  9. TNF-alpha is released rapidly in trout macrophages after stimulation with lipopolysaccharide and zymosan, and its secretion is dependent on TACE (显示 ADAM17 抗体)-like activity that is regulated by ERK (显示 MAPK1 抗体), JNK (显示 MAPK8 抗体) and p38MAPK (显示 MAPK14 抗体) signaling pathways.

  10. Recombinant, as well as native trout TNF-alpha, directly stimulates glucose uptake in trout muscle cells and provide evidence, for the first time in nonmammalian vertebrates, for a potential regulatory role of TNF-alpha in skeletal muscle metabolism.

Human Tumor Necrosis Factor (TNF) interaction partners

  1. GW1929 abolishes the TNFalpha-mediated decrease of ApoA-I (显示 APOA1 抗体) mRNA expression in both HepG2 and Caco-2 cells but does not block TNFalpha-mediated inhibition of ApoA-I (显示 APOA1 抗体) protein secretion by HepG2 cells.

  2. Our results indicate that TNFalpha gene -238G/A polymorphism increases the risk of developing psoriasis vulgaris among Indians.

  3. These results suggested that TNF-alpha -308 A allele was significantly associated with distant tumor metastasis in rectal cancer patients.

  4. This study provides the evidence to support that TNF-alpha involves in thoracic ossification of the ligamentum flavum probably through regulating cell proliferation via cyclin D1 (显示 CCND1 抗体) and c-Myc (显示 MYC 抗体), and promoting osteoblast differentiation via Osx (显示 MID1 抗体).

  5. results therefore demonstrate cancer epigenetics induces a loop of cancer-stroma-cancer interaction in omental microenvironment that promotes peritoneal metastasis of ovarian cancer cells via TNFalpha-TGFalpha-EGFR (显示 EGFR 抗体).

  6. Cystatin C (显示 CST3 抗体) significantly decreased the lipopolysaccharide-stimulated release and expression of tumor necrosis factor-alpha in monocyte and peripheral blood mononuclear cultures from healthy donors and Crohn's patients.

  7. Data show that pan (显示 SUPT6H 抗体)-caspase (显示 CASP3 抗体) inhibitors facilitated 5-fluorouracil (5-FU)-induced necroptosis mediated by secretion of tumor necrosis factor alpha (TNF-alpha) driven by nuclear factor kappaB (NF-kappaB (显示 NFKB1 抗体)) and required RIP1 (显示 UQCRFS1 抗体) kinase.

  8. The enhanced survival properties and decreased TNF signaling of rheumatoid arthritis (RA) low-density granulocytes, are likely to have important consequences for disease pathology and response to therapy.

  9. PRDX6 (显示 PRDX6 抗体) inhibited the carcinogenesis of hepatocellular carcinoma, and the calcium-independent phospholipase A2 (显示 PNPLA8 抗体) activity of PRDX6 (显示 PRDX6 抗体) promoted cancer cell death induced by TNF-alpha.

  10. The progression of pregnancy is accompanied by the concerted increase in TNFalpha and VEGF secretion and decrease in the production of their soluble receptors, but the expression of cell surface receptors does not depend on gestational age. The observed patterns of basal and stimulated expression of TNFalpha and VEGF may reflect the dual immune and morphogenetic roles of placental macrophages in gestation.

Mouse (Murine) Tumor Necrosis Factor (TNF) interaction partners

  1. MK2 (显示 KCNA2 抗体)-mediated phosphorylation of RIPK1 (显示 RIPK1 抗体) serves as a checkpoint within the TNF signaling pathway that integrates cell survival and cytokine production.

  2. TLR4 (显示 TLR4 抗体) activates CASPASE-8 (显示 CASP8 抗体) to cleave and remove the deubiquitinase cylindromatosis (CYLD (显示 CYLD 抗体)) in a TRIF (显示 RNF138 抗体)- and RIPK1 (显示 RIPK1 抗体)-dependent manner to disable necroptosis in macrophages.

  3. impaired TNF/TNFR2 (显示 TNFRSF1B 抗体) signaling enhances Th2 and Th17 polarization and aggravates allergic airway inflammation.

  4. The elevated cytotoxicity achieved by suppressing mTOR (显示 FRAP1 抗体) was a result of up-regulation of NKG2D (显示 KLRK1 抗体) and TNF-alpha. The inhibition of STAT5 (显示 STAT5A 抗体) pathways via siRNA interference or a specific inhibitor eliminated the up-regulation of NKG2D (显示 KLRK1 抗体) and TNF-alpha in rapamycin-treated Vgamma4 gammadelta T cells.

  5. this study shows that tumor produced TNF-alpha causes an upregulation of PD-L1 (显示 CD274 抗体) expression by tumor-associated monocytes

  6. differential regulation of exocytosis by TNF-alpha involves the actin cytoskeleton and is a necessary component for priming of the 2 major neutrophil antimicrobial defense mechanisms: oxygen radical generation and release of toxic granule contents.

  7. this study shows that vagotomy can increase tumor growth and worsen survival in a murine pancreatic cancer model mediated through tumor-associated macrophages and TNFalpha

  8. Adiponectin (显示 ADIPOQ 抗体), TNF-alpha, and LOX-1 (显示 OLR1 抗体) exert complex regulatory effects on the coronary microvascular endothelial function in atherosclerotic ApoE (显示 APOE 抗体) knockout mice.

  9. PRDX6 (显示 PRDX6 抗体) inhibited the carcinogenesis of hepatocellular carcinoma, and the calcium-independent phospholipase A2 (显示 LYPLA1 抗体) activity of PRDX6 (显示 PRDX6 抗体) promoted cancer cell death induced by TNF-alpha.

  10. Activation of CX3CR1 (显示 CX3CR1 抗体)(high)Ly6C(low) monocytes impaired motor learning and learning-related dendritic spine plasticity through tumor necrosis factor (TNF)-alpha-dependent mechanisms.

Pig (Porcine) Tumor Necrosis Factor (TNF) interaction partners

  1. TMZ pretreatment effectively reduced the myocardial damage caused by CME via inhibiting the PDCD4 (显示 PDCD4 抗体)/NF-kappaB (显示 NFKB1 抗体)/ TNF-alpha pathway in cardiomyocytes.

  2. TNF-alpha, secreted from activated Monocytes, mediates the downregulation of OTX2 (显示 OTX2 抗体) and essential retinal pigment epithelium genes.

  3. TNF-alpha induced MMP-13 (显示 MMP13 抗体) expression by condylar cells might be involved in the degradation of the juvenile condyle.

  4. TNF-alpha was able to promote theca interna cell proliferation. Our results suggest that TNF-alpha might play a role in hyperandrogenism, cortex thickness, and the increased ovary volume observed in polycystic ovaries.

  5. This study showed that the -791(C-->T) mutation of the TNF-alpha gene could be considered an important potential genetic marker of enterotoxigenic Escherichia coli F18 (显示 MAMLD1 抗体) resistance.

  6. Both Nsp1beta and Nsp11 of porcine reproductive and respiratory syndrome virus were demonstrated to be responsible for the inhibitory effect on TNF-alpha production in pulmonary alveolar macrophages.

  7. Study presents evidence demonstrating a single species of exotoxin ApxI, derived from A. pleuropneumoniae serotype 10, induces the expression and production of proinflammatory cytokines IL-1beta (显示 IL1B 抗体), IL-8 (显示 IL8 抗体) and TNF-alpha in porcine alveolar macrophages.

  8. the role of miR (显示 MYLIP 抗体)-181a in adipocyte differentiation by regulation of TNF-alpha

  9. The NOS (显示 NOS 抗体) inhibitor, L-NMMA, significantly suppressed the combined effects of HT and CORM-2 on TNFalpha-triggered NFkappaBp65 phosphorylation as well as decreased cell viability.

  10. High-volume hemofiltration improves hemodynamics and heart dysfunction in septic shock pigs, which may be attributed to reduction of TNF-alpha in myocardium but not in circulation.

Cow (Bovine) Tumor Necrosis Factor (TNF) interaction partners

  1. Data suggest that luteolytic factors (such as TNFa, interferon gamma (显示 IFNG 抗体), and PGF2a) control expression of MMP1 (显示 MMP1 抗体), other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.

  2. These results suggest that polymorphism of the TNFalpha-824 A>G gene and mTNFalpha protein expression play an important role in the pathogenesis of enzootic bovine leukosis.

  3. These results suggest that the endometrium might lower the TNF concentration in the blastocyst by (1) regulating TNF secretion into the uterine fluid and (2) inducing decreased TNF and TNFR2 (显示 TNFRSF1B 抗体) mRNA transcription in the embryo.

  4. There was a significant association between the proviral load and a low frequency of the G/G genotype of TNF-alpha at position -824.

  5. SNP in the TNF-alpha gene affects immune function and reproductive performance in dairy cows.

  6. Studied genotypic and expression profiling of partial TNF-alpha gene and its association with mastitis susceptibility in 129 crossbred cattle.

  7. Messenger RNA and protein levels of prostaglandin (PG) E synthase (PGES (显示 PTGES 抗体)), PGF2alpha receptor (PGFR), tumor necrosis factor-alpha (TNF) and Fas (显示 FAS 抗体) were found to be higher in the corpus luteum of pregnancy than in corpus luteum of the cycle.

  8. TNF-alpha up-regulates NaV1.7 (显示 SCN9A 抗体) mRNA in both adrenal chromaffin cells and dorsal root ganglia (DRG) neurons, highlighting the peripheral nociceptive mechanism of TNF-alpha

  9. These results provide evidence for a high prevalence of subclinical endometritis in repeat breeding cows as well as the involvement of TNFalpha and iNOS (显示 NOS2 抗体) pathways in the regulation of this pathological condition.

  10. Exposure to follicular fluid transiently increased the transcript levels of IL8 (显示 IL8 抗体) and PTGS2 (显示 PTGS2 抗体), and decreased the expression of SOD2 (显示 SOD2 抗体), GPX3 (显示 GPX3 抗体), DAB2 (显示 DAB2 抗体), and NR3C1 (显示 NR3C1 抗体). TNF and IL6 (显示 IL6 抗体) levels were also decreased while those of NAMPT (显示 NAMPT 抗体) were unaffected.

Horse (Equine) Tumor Necrosis Factor (TNF) interaction partners

  1. The results obtained showed that IL-6 (显示 IL6 抗体) expression in adipose tissue biopsies derived from animals with equine metabolic syndrome was enhanced while TNF-alpha levels of both groups were comparable.

  2. Data indicate that tumor necrosis factor-alpha production is closely related to ovarian steroid actions.

  3. These results indicate that in equine corpus luteum, cytokines TNF, IFNG (显示 IFNG 抗体) and FASL (显示 FASL 抗体) regulate nitric oxide activity, via eNOS (显示 NOS3 抗体) expression modulation.

  4. These data show the presence of cytokines TNF and IFNG (显示 IFNG 抗体), and their receptors, in the equine corpus luteum and indicate their potential involvement in regulation of luteal function.

  5. The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6 (显示 IL6 抗体), IL-10 (显示 IL10 抗体) and TNF-alpha, in horses with recurrent airway obstruction during exacerbation and in remission is reported.

Rabbit Tumor Necrosis Factor (TNF) interaction partners

  1. TUNEL staining was positively correlated with TNF-a protein expression. Our findings suggest that apoptosis can be induced in the vocal fold epithelium after 120min of modal intensity phonation. In contrast, shorter durations of vibration exposure do not result in apoptosis signaling.

  2. Inflammatory factors such as TNF-alpha can stimulate MMP-2 (显示 MMP2 抗体)/9 activity in corneal epithelium cells. This may be a potential manipulating mechanism of MMP expression in the pathogenesis of corneal diseases.

  3. The JNK (显示 MAPK8 抗体) pathway plays an important role in mechanical ventilation-stimulated TNF-alpha expression in alveolar macrophages, but the injury-stimulated IL-8 (显示 IL8 抗体) expression may be regulated by other signaling pathways.

  4. The TNFalpha-evoked Cl- current.

  5. IL-1beta (显示 IL1B 抗体) and TNF-alpha expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta (显示 IL1B 抗体) and TNF-alpha.

  6. Hypercapnia increased expression of TNFa and decreased expression of NFKB in acute lung injury models.

  7. In the early stages of myocardial ischemia, bone marrow stem cells are mobilized and home to ischemic myocardium with a concomitant increase in expression of cytokines VEGF (显示 VEGFA 抗体) and TNFalpha.

  8. Ammonium perchlorate can increase gene expressions of types I, III collagens, TGF-beta(1 (显示 TGFB1 抗体)) and TNF-alpha in lung of rabbits.

  9. TNFalpha may either be directly or indirectly involved in vascular damage following an embolic stroke. Moreover, TNFalpha may mediate some of the detrimental effects of tPA (显示 PLAT 抗体) on the vascular compartment

Rhesus Monkey Tumor Necrosis Factor (TNF) interaction partners

  1. These interactions result in the induction of the TNF signaling pathway, activation of apoptosis, and DNA-damage stress response.

  2. Findings showed that both mucosal compartments harbor similar percentages of memory CD4 (显示 CD4 抗体)(+) T cells and displayed comparable cytokine TNF-alpha responses to mitogenic stimulations prior to infection.

  3. Primary role for IL-1beta (显示 IL1B 抗体) and TNF-alpha in the triggering of preterm labor associated with inflammation or infection.

Goat Tumor Necrosis Factor (TNF) interaction partners

  1. Data indicate that three single-nucleotide polymorphisms were identified in tumor necrosis factor-alpha (TNF-alpha) gene.

Zebrafish Tumor Necrosis Factor (TNF) interaction partners

  1. The results reveal a crucial role for TNFalpha/TNFR2 (显示 TNFRSF1B 抗体) axis in the protection of the skin against DUOX1 (显示 DUOX1 抗体)-mediated oxidative stress.

  2. TNF alpha is the first molecule identified that is produced by dying retinal neurons and is necessary to induce Muller glia to proliferate in the zebrafish retinal regeneration response.

  3. The data suggest that Mycobacterium marinum SecA2 modulates adaptive immunity to promote granuloma stability, perhaps through induction of tumor necrosis factor alpha.

  4. TNF is not required for tuberculous granuloma formation, but maintains granuloma integrity indirectly by restricting mycobacterial growth within macrophages and preventing their necrosis.

  5. The main proinflammatory effects of fish TNF-alpha are mediated through the activation of endothelial cells and point to the complexity of the evolution that has taken place in the regulation of innate immunity by cytokines.

Tumor Necrosis Factor (TNF) 抗原简介

Antigen Summary

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Alternative names and synonyms associated with Tumor Necrosis Factor (TNF)

  • tumor necrosis factor (TNF superfamily, member 2) (TNF) 抗体
  • tumor necrosis factor (tnf) 抗体
  • tumour necrosis factor alpha-like (tnf-alpha) 抗体
  • tumor necrosis factor alpha (tnf-alpha) 抗体
  • lipopolysaccharide-induced TNF factor (LITAF) 抗体
  • tumor necrosis factor (TNF) 抗体
  • tumor necrosis factor (Tnf) 抗体
  • tumor necrosis factor alpha (TNF) 抗体
  • tumor necrosis factor b (TNF superfamily, member 2) (tnfb) 抗体
  • Cachectin 抗体
  • cTNF 抗体
  • DIF 抗体
  • RATTNF 抗体
  • tnf 抗体
  • TNF-a 抗体
  • Tnf-alpha 抗体
  • TNFa 抗体
  • tnfa-like 抗体
  • TNFalpha 抗体
  • Tnfsf1a 抗体
  • TNFSF2 抗体
  • xtnf 抗体

Protein level used designations for anti-Tumor Necrosis Factor (TNF) 抗体

tumor necrosis factor (TNF superfamily, member 2) , tumor necrosis factor alpha , tumor necrosis factor , tumour necrosis factor alpha , putative tumour necrosis factor alpha , LPS-induced TNF-alpha factor homolog , TNF-alpha factor , lipid-induced TNF-alpha factor , lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog , small integral membrane protein of lysosome/late endosome , tissue necrosis factor-alpha , APC1 protein , TNF, macrophage-derived , TNF, monocyte-derived , TNF-a , cachectin , tumor necrosis factor ligand superfamily member 2 , tumor necrosis factor-alpha , TNF-alpha , tumor-necrosis factor , tumour necrosis factor , ATP-binding cassette, sub-family F (GCN20), member 1 , TNF alpha , tumor necrosis factor, alpha , TNF2 , lta

GENE ID SPECIES
744399 Pan troglodytes
100136064 Oncorhynchus mykiss
100304592 Ictalurus punctatus
100134991 Xenopus (Silurana) tropicalis
100136034 Oncorhynchus mykiss
100137091 Salmo salar
374125 Gallus gallus
7124 Homo sapiens
21926 Mus musculus
24835 Rattus norvegicus
397086 Sus scrofa
280943 Bos taurus
443540 Ovis aries
100033834 Equus caballus
403922 Canis lupus familiaris
100135630 Cavia porcellus
100009088 Oryctolagus cuniculus
493755 Felis catus
715467 Macaca mulatta
100397484 Callithrix jacchus
101420445 Dasypus novemcinctus
494186 Pan troglodytes
101318178 Tursiops truncatus
100861232 Capra hircus
554167 Danio rerio
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