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anti-TRADD (TRADD) 抗体产品概述

Full name:
anti-TNFRSF1A-Associated Via Death Domain 抗体 (TRADD)
在www.antibodies-online.cn可供110 TNFRSF1A-Associated Via Death Domain (TRADD) 抗体的23不同的供货商。 再加上,我们可以发TRADD 蛋白 (14)TRADD 试剂盒 (3)和数多这个蛋白质的别的产品。 总共135 TRADD产品已列进来了。
别名:
9130005N23Rik, AA930854, Hs.89862, tradd, wu:fc59e02, zgc:103556
列出全部抗体 基因 基因ID UniProt
TRADD 8717 Q15628
TRADD 71609 Q3U0V2
TRADD 246756  

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引用最多的anti-TRADD 抗体

  1. Human Monoclonal TRADD Primary Antibody for IF, IP - ABIN968045 : He, Ting: A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells. in Molecular and cellular biology 2002 (PubMed)
    Show all 5 references for ABIN968045

  2. Human Monoclonal TRADD Primary Antibody for WB - ABIN967541 : Hsu, Shu, Pan, Goeddel: TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. in Cell 1996 (PubMed)
    Show all 3 references for ABIN967541

  3. Human Polyclonal TRADD Primary Antibody for EIA, FACS - ABIN955307 : Pointon, Harvey, Karaderi, Appleton, Farrar, Stone, Sturrock, Reveille, Weisman, Ward, Brown, Wordsworth: The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-associated death domain (TRADD). in Annals of the rheumatic diseases 2010 (PubMed)
    Show all 2 references for ABIN955307

  4. Human Polyclonal TRADD Primary Antibody for IHC (p), IHC - ABIN407974 : Chakraborty, Li, Tang, Xie, Puliyappadamba, Raisanen, Burma, Boothman, Cochran, Wu, Habib: Cytoplasmic TRADD confers a worse prognosis in glioblastoma. in Neoplasia (New York, N.Y.) 2013 (PubMed)

  5. Human Polyclonal TRADD Primary Antibody for IP, IHC - ABIN223257 : Chen, Texada, Duggan, Liang, Reden, Kooragayala, Langford: Surface calreticulin mediates muramyl dipeptide-induced apoptosis in RK13 cells. in The Journal of biological chemistry 2005 (PubMed)

  6. Human Polyclonal TRADD Primary Antibody for IF (p), IHC (p) - ABIN673314 : Chen, Zhang, Zhang, Li, Sun: Hydrogen sulfide protects against TNF-α induced neuronal cell apoptosis through miR-485-5p/TRADD signaling. in Biochemical and biophysical research communications 2016 (PubMed)

  7. Dog (Canine) Polyclonal TRADD Primary Antibody for WB - ABIN2792121 : Miyagawa, Yamai, Sakaguchi, Kiyohara, Tsukamoto, Kimoto, Nakamura, Lee, Tsai, Chiang, Shimoda, Harada, Tahira, Hayashi, Horiuchi: Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus. in Rheumatology (Oxford, England) 2008 (PubMed)

更多抗TRADD的相互作用对抗体

Human TNFRSF1A-Associated Via Death Domain (TRADD) interaction partners

  1. These data for the first time identifies miR (显示 MLXIP 抗体)-485-5p/TRADD axis in hydrogen sulfide (显示 SQRDL 抗体) protecting against TNF-alpha (显示 TNF 抗体)-induced neuronal cell apoptosis.

  2. By reducing the levels of TRADD, wild type CFTR suppresses downstream proinflammatory NFkappaB signaling.

  3. NPM (显示 NPM1 抗体)-RAR (显示 RARA 抗体) binding to TRADD selectively inhibits caspase (显示 CASP3 抗体) activation, while allowing activation of NFkappaB (显示 NFKB1 抗体) and JNK (显示 MAPK8 抗体)

  4. The release of extracellular vesicles was triggered by TNFA (显示 TNF 抗体) from BEAS-2b cells.TNFA-triggered extracellular vesicles contained TNFR1 (显示 TNFRSF1A 抗体) and TRADD.

  5. MicroRNA-30c-2-3p negatively regulates NF-kappaB (显示 NFKB1 抗体) signaling and cell cycle progression through downregulation of TRADD and CCNE1 (显示 CCNE1 抗体) in breast cancer.

  6. domains of calmodulin (显示 CALM1 抗体) mediate FADD (显示 FADD 抗体) and TRADD interaction

  7. PA induced the apoptosis of HUVECs by initiating the death pathway (TNF-R1 (显示 TNFRSF1A 抗体)/TRADD/caspases 8 pathway), whereas AA enhanced cell survival to protect vascular endothelial cells by activating the survival pathway (TNF-R1 (显示 TNFRSF1A 抗体)/RIP (显示 HRB 抗体)/NF-kappaB (显示 NFKB1 抗体) 50/NF-kappaB (显示 NFKB1 抗体) 65).

  8. Biologic assessment found that NPM (显示 NPM1 抗体)-RAR (显示 RARA 抗体) expression impaired TNF (显示 TNF 抗体)-induced signaling through TRADD, blunting TNF (显示 TNF 抗体)-mediated activation of caspase-3 (CASP3 (显示 CASP3 抗体)) and caspase-8 (CASP8 (显示 CASP8 抗体)), to ultimately block apoptosis.

  9. TRADD gene expression was knocked down by an antisense oligonucleotide.

  10. structure-based mutations of TNFR-1 (显示 TNFRSF1A 抗体) (P367A and P368A), TRADD (F266A), and RIP1 (显示 UQCRFS1 抗体) (M637A and R638A) disrupted formation of the death domain (DD) complex and prevented stable interactions among those DDs

Mouse (Murine) TNFRSF1A-Associated Via Death Domain (TRADD) interaction partners

  1. TRADD knockout blunts pressure overload-induced cardiac hypertrophy through mediating TAK1 (显示 NR2C2 抗体)/p38 MAPK (显示 MAPK14 抗体) but not AKT (显示 AKT1 抗体) phosphorylation

  2. Data indicate that ASK1 (显示 MAP3K5 抗体) activation stimulated the activity of the transcription factor FoxO3a (显示 FOXO3 抗体), which increased the abundance of the apoptosis-promoting adaptor protein TRADD, leading to activation of caspase 8 (显示 CASP8 抗体).

  3. data indicate that TRADD shuttles dynamically from the cytoplasm into the nucleus to modulate the interaction between p19(Arf (显示 CDKN2A 抗体)) and its E3 ubiquitin ligase (显示 MUL1 抗体) ULF (显示 TRIP12 抗体), thereby promoting p19(Arf (显示 CDKN2A 抗体)) protein stability and tumour suppression

  4. Data suggest that deficiency of TRADD sensitizes cells to TRAIL-induced apoptosis, and that enhanced cell death in TRADD(-/-) MEFs is associated with defective NF-kappaB (显示 NFKB1 抗体) activation.

  5. TRADD is required for recruitment of receptor interacting protein 1 (显示 RIPK1 抗体) and TNFR (显示 TNFRSF1A 抗体)-associated factor 2 to the DR3 (显示 TNFRSF25 抗体) signaling complex and for the ubiquitination of receptor interacting protein 1 (显示 RIPK1 抗体)

  6. We show that TRADD is recruited to the TRAIL-receptor complex, and RIP1 (显示 RALBP1 抗体) recruitment is mediated by TRADD.

  7. TRADD may be involved in IFN-gamma (显示 IFNG 抗体) signaling by forming a complex with STAT1 (显示 STAT1 抗体)-alpha within the nucleus and regulating IFN-gamma (显示 IFNG 抗体)-mediated STAT1 (显示 STAT1 抗体)-alpha activation.

  8. Tradd activates distinct mechanisms of apoptosis from the nucleus and the cytoplasm.

  9. silencing TRADD expression with small-interfering RNA reduced neuronal apoptosis and subsequent microglial and astroglial activation

  10. TRADD is a multifunctional protein crucial both for TNFR1 (显示 TNFRSF1A 抗体) signaling and other signaling pathways relevant to immune responses.

Cow (Bovine) TNFRSF1A-Associated Via Death Domain (TRADD) interaction partners

  1. TNF (显示 TNF 抗体) binding induces release of AIP1 (DAB2IP (显示 DAB2IP 抗体)) from TNFR1 (显示 TNFRSF1A 抗体), resulting in cytoplasmic translocation and concomitant formation of an intracellular signaling complex comprised of TRADD, RIP1 (显示 RALBP1 抗体), TRAF2 (显示 TRAF2 抗体), and AIPl.

TRADD 抗原简介

Antigen Summary

The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.

Alternative names and synonyms associated with TRADD

  • TNFRSF1A-associated via death domain (TRADD) 抗体
  • TNFRSF1A-associated via death domain (LOC100337888) 抗体
  • conjugal transfer protein D (traDd) 抗体
  • TNFRSF1A-associated via death domain (Tradd) 抗体
  • TNFRSF1A-associated via death domain (tradd) 抗体
  • tnfrsf1a-associated via death domain (tradd) 抗体
  • tnfrsf1a-associated via death domain protein (LOC100136668) 抗体
  • 9130005N23Rik 抗体
  • AA930854 抗体
  • Hs.89862 抗体
  • tradd 抗体
  • wu:fc59e02 抗体
  • zgc:103556 抗体

Protein level used designations for TRADD

TNFRSF1A-associated via death domain , conjugal transfer protein D , TNFR1-associated death domain protein , tumor necrosis factor receptor type 1 associated death domain protein , tumor necrosis factor receptor type 1-associated DEATH domain protein , tumor necrosis factor receptor-1-associated protein , TNF receptor 1 associated signal transducer , TNFR1-associated DEATH domain protein , Tumor necrosis factor receptor type 1-associated DEATH domain protein , TNFRSF1A-associated via death domain protein

GENE ID SPECIES
415700 Gallus gallus
454154 Pan troglodytes
100337888 Oryctolagus cuniculus
7369642 Agrobacterium radiobacter K84
8717 Homo sapiens
71609 Mus musculus
246756 Rattus norvegicus
611262 Canis lupus familiaris
504707 Bos taurus
733418 Xenopus laevis
58130 Danio rerio
100136668 Oncorhynchus mykiss
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