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抗Mouse (Murine) NFKBIB 抗体:
抗Human NFKBIB 抗体:
抗Rat (Rattus) NFKBIB 抗体:
Human Monoclonal NFKBIB Primary Antibody for ELISA, WB - ABIN969314
Chen, Vallee, Wu, Vu, Sondek, Ghosh: Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras. in Molecular and cellular biology 2004
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IkappaBbeta has essential functions within the Rel-NFkappaB generation module, specifically for the RelA:RelA homodimer, which controls a subset of NFkappaB target genes.
these results mechanistically link the innate immune response mediated by IkappaBbeta/NF-kappaB (显示 NFKB1 抗体) to ET-1 (显示 EDN1 抗体) expression and potentially reveal therapeutic targets for patients with Gram-negative septic shock.
Dengue virus protease interacts with both IkappaBalpha (显示 NFKBIA 抗体) and IkappaBbeta cleaving them in a mouse hemorrhage model.
sustained NF-kappaB (显示 NFKB1 抗体) activity mediated by IkappaBbeta protects against hyperoxic lung injury through increased expression of antiapoptotic genes
Findings represent a necessary but not sufficient role of IkappaBbeta in preventing oxidant stress-induced cell death.
IkappaBbeta is an essential co-activator for LPS (显示 TLR4 抗体)-induced IL-1beta (显示 IL1B 抗体) transcription in vivo.
IkappaBbeta acts through p65 (显示 NFkBP65 抗体):c-Rel (显示 NFkBP65 抗体) dimers to maintain prolonged expression of TNF-alpha (显示 TNF 抗体)
data suggest that RelA (显示 NFkBP65 抗体) is liberated during LPS (显示 TLR4 抗体)-induced pulmonary inflammation by the regulated degradation of both IkappaB-alpha (显示 NFKBIA 抗体) and IkappaB-beta
temporal control of NF-kappaB (显示 NFKB1 抗体) activation by the coordinated degradation and synthesis of IkappaB proteins
beta-TrCP1 (显示 BTRC 抗体) contributes to, but is not absolutely required for, the degradation of I kappa B and beta-catenin (显示 CTNNB1 抗体)
our data establish the importance of a novel tumor suppressive IKBB gene in abrogating angiogenesis in NPC (显示 NPC1 抗体) via the NF-kappaB (显示 NFKB1 抗体) signalling pathway.
IkappaBbeta may be a novel target for transcription factors of the HMG (显示 SSRP1 抗体)-box SRY (显示 SRY 抗体)/Sox (显示 PIPOX 抗体) family and imply a potential role for NF-kappaB (显示 NFKB1 抗体)/IkappaBbeta in spermatogenesis
Data show that increased nuclear factor-kappaB (NF-kB) activity in the amnion during labor is associated with an increase in the expression of NF-kBp65 and of the NF-kB binding proteins IkBa (显示 NFKBIA 抗体), IkBb-1 and IkBb-2.
VEGF (显示 VEGFA 抗体) increased Mn-superoxide dismutase (显示 SOD2 抗体) promoter activity, an effect that was dependent on a second intronic NF-kappaB (显示 NFKB1 抗体) consensus motif.
data indicate that inhibition of NFkappa-B activity by the hepatitis C virus core protein might be related to its physical interaction with and interrupted nuclear localization of IKKbeta (显示 IKBKB 抗体)
None of the NFKBIB SNPs are associated with pneumococcal susceptibility.
NF-kappaB (显示 NFKB1 抗体), IkappaB-alpha (显示 NFKBIA 抗体), IkappaB-beta mRNA decreased significantly after weight loss.
increased I-kappaBbeta expression reversed NF-kappaB (显示 NFKB1 抗体) activation in cancer cells, compensating for the loss of I-kappaBalpha (显示 NFKBIA 抗体) via TGase 2 (显示 TGM2 抗体) polymerization.
NFKBIA (显示 NFKBIA 抗体) and NFKBIB are not likely to harbor ovarian cancer risk alleles.
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
, NF-kappa-B inhibitor beta
, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta
, TR-interacting protein 9
, thyroid receptor-interacting protein 9