anti-MAP3K14 (MAP3K14) 抗体产品概述

在www.antibodies-online.cn可供132 Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14) 抗体的25不同的供货商。 再加上,我们可以发MAP3K14 蛋白 (9)和数多这个蛋白质的别的产品。 总共153 MAP3K14产品已列进来了。
别名:
aly, F23F1.4, F23F1_4, FLH21957, FTDCR1B, HGK, HS, HSNIK, MEKKK4, mitogen-activated protein kinase kinase kinase 14, Nik
列出全部抗体 基因 基因ID UniProt
MAP3K14 9020 Q99558
MAP3K14 360640  
MAP3K14 53859 Q9WUL6

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抗Rat (Rattus) MAP3K14 抗体:

抗Mouse (Murine) MAP3K14 抗体:

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更多抗MAP3K14的相互作用对抗体

Human Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14) interaction partners

  1. OLFM1 (显示 OLFM1 抗体) is a negative regulator of non-canonical NF-kappaB (显示 NFKB1 抗体) signalling by interacting with and inhibiting NIK. Thus, OLFM1 (显示 OLFM1 抗体) may serve as a valuable biomarker and therapeutic target for colorectal cancer (CRC (显示 CALR 抗体)) patients.

  2. The expression of OTUD7B (显示 OTUD7B 抗体) and NIK were negatively correlated in non-small cell lung cancer tumor samples. the higher expression of NIK was related to more lymph node metastasis and later TNM (显示 ODZ1 抗体) stage. high OTUD7B (显示 OTUD7B 抗体)/low NIK index can predict an good prognosis.

  3. NIK expression was significantly increased in the tumor tissue of patients with breast carcinoma, which may be an important factor that affects the prognosis of these patients.

  4. This study identified two novel independent loci (MAP3K14 and CARD9 (显示 CARD9 抗体)) strongly associated with joint damage in Mexican Americans and European Americans and a few shared loci showing suggestive evidence for association.

  5. The forced expression of NDRG2 (显示 NDRG2 抗体) in ATL cells down-regulates not only the canonical pathway by inhibiting AKT (显示 AKT1 抗体) signaling but also the non-canonical pathway by inducing NF-kappaB (显示 NFKB1 抗体)-inducing kinase (NIK) dephosphorylation via the recruitment of PP2A (显示 PPP2R4 抗体)

  6. NIK(+) endothelial cells may play an important role in the persistence of synovitis

  7. Data suggest microRNA302c, but not microRNA520e, promotes replication of influenza A virus H3N2 although the two microRNAs target same site of NFkappaB (显示 NFKB1 抗体)-inducing kinase (MAP3K14) 3prime untranslated region; studies were conducted in lung epithelial cells.

  8. TWEAK (显示 TNFSF12 抗体) induces noncanonical NF-kappaB (显示 NFKB1 抗体) signaling and signal-specific regulation of NIK mRNA expression.

  9. by demonstrating a critical role of NIK in mediating NF-kappaB (显示 NFKB1 抗体) activation and BAG3 (显示 BAG3 抗体) induction upon ST80/Bortezomib cotreatment, our study provides novel insights into mechanisms of resistance to proteotoxic stress in RMS

  10. Loss-of-function mutations in NIK can cause B-cell lymphopenia, hypogammaglobulinemia, impaired ICOSL (显示 ICOSLG 抗体) expression, and disordered T helper cell and NK cell function.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14) interaction partners

  1. this study demonstrates that although NIK (显示 MAP4K4 抗体) is dispensable for thymocyte development, it has a cell-intrinsic role in regulating the homeostasis and function of peripheral T cells

  2. Using a novel conditional mutant of NIK (显示 MAP4K4 抗体), the authors could show in vivo that NIK (显示 MAP4K4 抗体) signaling in thymic epithelial cells is essential for the thymic hardwiring of gammadelta T cell cytokine production.

  3. NIK (显示 MAP4K4 抗体) not only contributes to lymphoid organogenesis, inflammation and cell survival but also to TNFR1 (显示 TNFRSF1A 抗体)/RIP1 (显示 RALBP1 抗体)-dependent cell death independently of the alternative NF-kappaB (显示 NFKB1 抗体) pathway.

  4. This study demonstrated that NFkappaB-inducing kinase inhibits NFkappaB activity specifically in neurons of the CNS.

  5. results assign NIK (显示 MAP4K4 抗体)-induced alternative NF-kappaB (显示 NFKB1 抗体) signaling a master regulatory role in B-cells, starting from the T1 stage and also show that B-1 B cells are less dependent on this pathway, presumably owing to the existence of alternative pathways yet to be determined

  6. NIK (显示 MAP4K4 抗体), and thus probably the noncanonical NF-kappaB (显示 NFKB1 抗体) pathway, is critical to allow DCs to acquire the capacity to cross-present antigen and prime CD8 (显示 CD8A 抗体) T cells after exposure to licensing stimuli.

  7. Deletion of NIK (显示 MAP4K4 抗体) in adult mice results in decreases in B cell populations in lymph nodes and spleen, similar to what is observed upon blockade of BAFF (显示 TNFSF13B 抗体).

  8. We identify NIK (显示 MAP4K4 抗体) as a critical negative regulator of beta cell function, as pharmacological NIK (显示 MAP4K4 抗体) activation results in impaired glucose-stimulated insulin (显示 INS 抗体) secretion in mouse and human islets.

  9. the NIK (显示 MAP4K4 抗体) in thymic stroma may be critically involved in the differentiation of most NKT (显示 CTSL1 抗体) cell subsets (although the level of NIK (显示 MAP4K4 抗体) dependence may vary among the subsets), and also the NIK (显示 MAP4K4 抗体) in NKT (显示 CTSL1 抗体)-alphabeta cells may be dispensable for their effector function.

  10. CHIP/TRAF3 (显示 TRAF3 抗体)/NIK (显示 MAP4K4 抗体) interactions recruit NIK (显示 MAP4K4 抗体) to E3 ligase complexes for ubiquitination and degradation, thus maintaining NIK (显示 MAP4K4 抗体) at low levels

MAP3K14 抗原简介

Antigen Summary

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.

Alternative names and synonyms associated with MAP3K14

  • mitogen-activated protein kinase kinase kinase 14 (MAP3K14) 抗体
  • mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) 抗体
  • mitogen-activated protein kinase kinase kinase 14 (Map3k14) 抗体
  • mitogen-activated protein kinase kinase kinase 14 (MAPKKK14) 抗体
  • aly 抗体
  • F23F1.4 抗体
  • F23F1_4 抗体
  • FLH21957 抗体
  • FTDCR1B 抗体
  • HGK 抗体
  • HS 抗体
  • HSNIK 抗体
  • MEKKK4 抗体
  • mitogen-activated protein kinase kinase kinase 14 抗体
  • Nik 抗体

Protein level used designations for MAP3K14

NF-kappa-beta-inducing kinase , serine/threonine protein-kinase , serine/threonine-protein kinase NIK , HPK/GCK-like kinase HGK , MAPK/ERK kinase kinase kinase 4 , MEK kinase kinase 4 , Ste20 group protein kinase HGK , hepatocyte progenitor kinase-like/germinal center kinase-like kinase , nck-interacting kinase , NF kappa B-inducing kinase , Nfkb inducing kinase , alymphoplasia , protein kinase

GENE ID SPECIES
9020 Homo sapiens
9448 Homo sapiens
360640 Rattus norvegicus
817555 Arabidopsis thaliana
53859 Mus musculus
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