Use your antibodies-online credentials, if available.
抗Human Integrin beta 2 抗体:
抗Mouse (Murine) Integrin beta 2 抗体:
抗Rat (Rattus) Integrin beta 2 抗体:
Mouse (Murine) Monoclonal Integrin beta 2 Primary Antibody for FACS, Func - ABIN457404
Abraham, Miller: Molecular mechanisms of IL-2 gene regulation following costimulation through LFA-1. in Journal of immunology (Baltimore, Md. : 1950) 2001
Show all 10 Pubmed References
Mouse (Murine) Monoclonal Integrin beta 2 Primary Antibody for FACS, Func - ABIN457348
Avni, Pur, Yefenof, Baniyash: Complement receptor 3 of macrophages is associated with galectin-1-like protein. in Journal of immunology (Baltimore, Md. : 1950) 1998
Show all 9 Pubmed References
Mouse (Murine) Monoclonal Integrin beta 2 Primary Antibody for FACS, Func - ABIN457430
Sakurai, Taguchi, Anand, Ambati, Gragoudas, Miller, Adamis, Ambati: Targeted disruption of the CD18 or ICAM-1 gene inhibits choroidal neovascularization. in Investigative ophthalmology & visual science 2003
Show all 8 Pubmed References
Mouse (Murine) Monoclonal Integrin beta 2 Primary Antibody for BR, IHC (f) - ABIN2689033
Driessens, van Hulten, Zuurbier, La Rivière, Roos: Inhibition and stimulation of LFA-1 and Mac-1 functions by antibodies against murine CD18. Evidence that the LFA-1 binding sites for ICAM-1, -2, and -3 are distinct. in Journal of leukocyte biology 1997
Show all 7 Pubmed References
Mouse (Murine) Monoclonal Integrin beta 2 Primary Antibody for BR, Func - ABIN1176975
Isobe, Yagita, Okumura, Ihara: Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1. in Science (New York, N.Y.) 1992
Show all 6 Pubmed References
Human Monoclonal Integrin beta 2 Primary Antibody for FACS, Func - ABIN192094
Cera, Fabbri, Molendini, Corada, Orsenigo, Rehberg, Reichel, Krombach, Pardi, Dejana: JAM-A promotes neutrophil chemotaxis by controlling integrin internalization and recycling. in Journal of cell science 2009
Show all 20 Pubmed References
Human Monoclonal Integrin beta 2 Primary Antibody for WB - ABIN1882257
Chen, Xie, Nishida, Li, Walz, Springer: Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2. in Proceedings of the National Academy of Sciences of the United States of America 2010
Show all 5 Pubmed References
Human Monoclonal Integrin beta 2 Primary Antibody for FACS, Func - ABIN94005
Nakayama, Yoshizaki, Prinetti, Sonnino, Mauri, Takamori, Ogawa, Iwabuchi: Lyn-coupled LacCer-enriched lipid rafts are required for CD11b/CD18-mediated neutrophil phagocytosis of nonopsonized microorganisms. in Journal of leukocyte biology 2008
Show all 19 Pubmed References
Human Monoclonal Integrin beta 2 Primary Antibody for FACS, Func - ABIN94008
Sewald, Gebert-Vogl, Prassl, Barwig, Weiss, Fabbri, Osicka, Schiemann, Busch, Semmrich, Holzmann, Sebo, Haas: Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin. in Cell host & microbe 2008
Show all 20 Pubmed References
Human Monoclonal Integrin beta 2 Primary Antibody for FACS, Func - ABIN94007
Morova, Osicka, Masin, Sebo: RTX cytotoxins recognize beta2 integrin receptors through N-linked oligosaccharides. in Proceedings of the National Academy of Sciences of the United States of America 2008
Show all 20 Pubmed References
CD18 deficiency curbs methionine-choline-deficient-mediated liver injury by limiting the activation of innate immune cells in the liver without compromising intrahepatic cytokine activation
results identify a role for Caveolin (Cav (显示 CA5A 抗体))1in membrane organization and beta2 integrin Lfa1 (显示 ITGAL 抗体) function in primary CD8 (显示 CD8A 抗体) T cells.
Coro1A (显示 CORO1A 抗体) represents an important novel player in integrin biology, with key functions in polymorphonuclear neutrophils trafficking during innate immunity.
EAE induced by weak activation of innate immunity requires the NLRP3 inflamma (显示 CXCR4 抗体)some and (显示 CXCR2 抗体)is sensitive to interferon-beta treatment
These results identify CD47 (显示 CD47 抗体) as an important regulator of LFA-1 (显示 ITGAL 抗体) and VLA-4 integrin-adhesive functions in T cell proliferation.
lymphatic vessel expansion occurs in two distinct phases; the first wave of expansion is dependent on IL-7 (显示 IL7 抗体); the second phase, responsible for leukocyte exit from the glands, is regulated by lymphotoxin (显示 LTB 抗体) (LT)betaR signaling
both GDF-15 (显示 GDF15 抗体) and TGF-beta1 (显示 TGFB1 抗体) counteract chemokine (显示 CCL1 抗体)-induced integrin activation on neutrophils via the ALK-5 (显示 TGFBR1 抗体)/TGF-betaRII heterodimer.
the Slam (显示 SLAMF1 抗体) locus has an overall inhibitory role during NK cell activation that is solely dependent on 2B4 (显示 CD244 抗体). This effect is influenced by cytokines and leads to suppression of LFA-1 (显示 ITGAL 抗体) activity.
Wild-type C57BL/6 mice with pristane-induced lupus developed a strong IFN signature, which was absent in immunoglobulin-deficient (muMT), C3(-/-) , and CD18(-/-) mice.
Study suggest an important impact of NKT (显示 CTSL1 抗体) cells and postulate a critical function for LFA-1 (显示 ITGAL 抗体) during processes of liver regeneration.
findings suggest the partitioning in soluble CD18 to reflect a compensatory anti-inflammatory response syndrome and hyperinflammation, respectively, manifested as part of sepsis.
activation of LFA-1 (显示 ITGAL 抗体) (alphaLbeta2) and Mac-1 (显示 ITGAM 抗体) (alphaMbeta2), two subfamilies of integrin beta2 complexes, on human primary monocytes following platelet releasate treatment
membrane-bound lymphotoxin-beta receptor (LTbetaR) and CXC chemokine receptor (显示 CXCR4 抗体) 2 (CXCR2 (显示 CXCR2 抗体)), is involved in type B EAE development
data suggest that regulation of LFA-1 (显示 ITGAL 抗体) is one reason for the different activity of NK cells during differentiation
The single nucleotide polymorphism rs1143678 substitutes Pro(1146) for Ser (显示 SIGLEC1 抗体) in the integrin alphaM cytoplasmic tail generates a noncanonical 14-3-3zeta (显示 YWHAZ 抗体) binding site that modulates integrin alphaM(PS)beta2 outside-in signaling
this study shows that cross-talk between LFA-1 (显示 ITGAL 抗体) and Notch1 (显示 NOTCH1 抗体) through the Akt (显示 AKT1 抗体)/ERK (显示 EPHB2 抗体)-GSK3beta (显示 GSK3b 抗体) signaling enhances T cell differentiation toward Th1 (显示 TH1L 抗体)
FRbeta (显示 FOLR2 抗体) as a novel CD11b/CD18 (显示 ITGAM 抗体) regulator for trafficking and homing of a subset of macrophages on collagen.
The results show that with LFA-1 (显示 ITGAL 抗体) antibodies, we can activate LFA-1 (显示 ITGAL 抗体) and inhibit alpha4beta1, inhibit both LFA-1 (显示 ITGAL 抗体) and alpha4beta1, inhibit LFA-1 (显示 ITGAL 抗体) but not alpha4beta1, or not affect LFA-1 (显示 ITGAL 抗体) or alpha4beta1
K152 and D120 within the PH domain of SKAP55 (显示 SKAP1 抗体) regulate plasma membrane targeting and T cell receptor-mediated activation of LFA-1 (显示 ITGAL 抗体).
LIGHT and LTBR (显示 LTBR 抗体) interaction increases the survival and proliferation of human bone marrow-derived mesenchymal stem cells, and therefore, LIGHT might play an important role in stem cell therapy.
Identification of numerous variations in exonic and intronic regions within the ITGB2 gene in Bos taurus and indicus screened for bovine leukocyte adhesion deficiency.
intramammarily administered lipopolysaccharides seem to play an important role in modulating L-selectin (显示 SELL 抗体) and beta2 integrin expression on circulating bovine polymorphonuclear leukocytes
A delay in apoptosis was demonstrated in CD18-deficient bovine neutrophils and this appeared to be closely associated with lowered signalling via [Ca2 (显示 CA2 抗体)+]i, diminished annexin V (显示 ANXA5 抗体) expression on the cell surface, and decreased caspase 3 (显示 CASP3 抗体) activity in lysates
The I-EGF (显示 EGF 抗体)-3 domain of bovine CD18 (amino acid residues 541-581) is critical for conferring species-specific susceptibility to Mannheimia haemolytica leukotoxin.
These results clearly indicate that the bovine CD18 subunit of beta(2)-integrins is the functional receptor for M. haemolytica Lkt.[ruminant-specific leukotoxin]
study provides evidence that the expression of CD18 was downregulated by the plasma glycoforms of alpha-1 acid glycoprotein (显示 ORM1 抗体) and inhibited the chemotaxis of monocytes
Loss of CD18 is associated with bovine leukocyte adhesion deficiency.
Intact signal peptide of CD18, the beta-subunit (显示 POLG 抗体) of beta2-integrins, renders ruminants susceptible to Mannheimia haemolytica leukotoxin.
CR3 (显示 ITGAM 抗体) plays a cardinal (显示 CARD8 抗体) role in beta-glucan signalling in porcine neutrophils, while macrophages use a more diverse receptor array to detect and respond towards beta-glucans.
The expression of zona pellucida glycoprotein 3 (显示 ZP3 抗体) and integrin beta-2 in oocytes after brilliant cresyl blue staining is reported.
early CD18 downregulation is profitable for the host in a situation with an intense LPS (显示 IRF6 抗体) stimulus
It is concluded that porcine CD18 is necessary to mediate A. pleuropneumoniae ApxIIIA toxin-induced leukolysis.
Integrin CD11c (显示 ITGAX 抗体)/CD18 alpha-chain (显示 FCGRT 抗体) phosphorylation is functionally important.
The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor)
, cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta
, complement receptor C3 beta-subunit
, complement receptor C3 subunit beta
, integrin beta chain, beta 2
, integrin beta-2
, leukocyte cell adhesion molecule CD18
, leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C
, Mac-1 beta
, lymphocyte function associated antigen 1
, macrophage antigen-1 beta
, CD18 subunit
, Leu-CAM receptor
, integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2)
, integrin beta 2 subunit
, CD18 leukocyte adhesion molecule
, antigen CD18
, integrin beta-2 chain
, integrin beta 2
, integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1
, integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
, macrophage antigen 1 (mac-1) beta subunit)
, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta
, Complement receptor C3 subunit beta
, Integrin beta-2
, integrin beta-2 subunit
, integrin subunit beta 2 S homeolog
, integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)