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抗Mouse (Murine) IL1B 抗体:
抗Rat (Rattus) IL1B 抗体:
抗Human IL1B 抗体:
Human Monoclonal IL1B Primary Antibody for CyTOF, FACS - ABIN4899223
Yates, Burgess, Kocsis-Angle, Antal, Dority, Embury, Piotrkowski, Brunden: Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. in Journal of neurochemistry 2000
Show all 15 Pubmed References
Human Monoclonal IL1B Primary Antibody for CyTOF, FACS - ABIN4899224
Oliver, Lovric, Yu, Christou, Aiken, Cooper, Walsh: Development of a Novel Model for the Assessment of Dead-Space Management in Soft Tissue. in PLoS ONE 2015
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Dog (Canine) Polyclonal IL1B Primary Antibody for IF (p), IHC (p) - ABIN728503
Zhong, Shu, Wang, Luo, Zhong, Ran, Zheng, Yin, Ling: Enhanced homing of mesenchymal stem cells to the ischemic myocardium by ultrasound-targeted microbubble destruction. in Ultrasonics 2011
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Bacteria Polyclonal IL1B Primary Antibody for ELISA, EM - ABIN269770
Petrovski, Ayna, Majai, Hodrea, Benko, Mádi, Fésüs: Phagocytosis of cells dying through autophagy induces inflammasome activation and IL-1β release in human macrophages. in Autophagy 2011
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Mouse (Murine) Polyclonal IL1B Primary Antibody for Neut, WB - ABIN223538
Scott, Ma, Viriyakosol, Terkeltaub, Liu-Bryan: Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals. in Journal of immunology (Baltimore, Md. : 1950) 2006
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Dog (Canine) Polyclonal IL1B Primary Antibody for IHC, ELISA - ABIN1582289
Choi, Lim, Hwang, Lee, Cho, Kim: Anti-ischemic and anti-inflammatory activity of (S)-cis-verbenol. in Free radical research 2010
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Human Polyclonal IL1B Primary Antibody for IHC (p), IHC - ABIN446969
Omran, Peng, Zhang, Xiang, Xue, Gan, Kong, Yin: Interleukin-1β and microRNA-146a in an immature rat model and children with mesial temporal lobe epilepsy. in Epilepsia 2012
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Mouse (Murine) Monoclonal IL1B Primary Antibody for IP, Neut - ABIN1176987
Fei, Gott, Edwards, Schuyler: Experimental hypersensitivity pneumonitis: in vitro effects of interleukin-2 and interferon-gamma. in The Journal of laboratory and clinical medicine 1995
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Mouse (Murine) Polyclonal IL1B Primary Antibody for ELISA, FACS - ABIN4324365
Triantafilou, Kar, Vakakis, Kotecha, Triantafilou: Human respiratory syncytial virus viroporin SH: a viral recognition pathway used by the host to signal inflammasome activation. in Thorax 2012
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Human Monoclonal IL1B Primary Antibody for FACS - ABIN4895765
Hussain, Kong, Jordan, Conrad, Madden, Fokt, Priebe, Heimberger: A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients. in Cancer research 2007
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Leukocyte expression of IL-1beta was detectable only following injury, which activated leukocytes throughout zebrafish embryos in a caspase (显示 CASP3 抗体) dependent manner.
Embryo and larva leukocytes upregulate IL-1beta expression proportional to the dose of ultraviolet radiation exposure in an immune response at the organismal level.
findings reveal that the Il-1beta-Myd88 (显示 MYD88 抗体) axis and NADPH oxidase (显示 NOX1 抗体)-mediated ROS (显示 ROS1 抗体) signaling are two independent pathways that differentially regulate neutrophil migration during sterile inflammation.
the expression levels of IL-1beta and TNF-alpha in high cholesterol diet (HCD)-fed zebrafish larvae
These results represent the first demonstration of processing and secretion of zebrafish IL-1beta in response to a pathogen.
Following vasectomy, IL1alpha (显示 IL1A 抗体), IL1beta, IL1ra (显示 IL1RN 抗体), IL10 (显示 IL10 抗体), and TNF-alpha (显示 TNF 抗体) may mediate immune reaction in whole epididymis, whereas IL6 (显示 IL6 抗体) and TGF-beta1 (显示 TGFB1 抗体) may mediate regionally different immune response primarily in the lower part of epididymis.
Elevations of CO2 cause oligomerization of the inflammasome components ASC (显示 STS 抗体), NLRP3 (显示 NLRP3 抗体), caspase 1 (显示 CASP1 抗体), thioredoxin interacting protein (显示 TXNIP 抗体), and calreticulin (显示 CALR 抗体) - a protein from endoplasmic reticulum, leading to IL-1beta synthesis. An increased production rate of MPs containing elevated amounts of IL-1beta persists for hours after short-term exposures to elevated CO2
dimerized or endogenous caspase-8 (显示 CASP8 抗体) can also directly cleave IL-1beta into its biologically active form, in the absence of canonical inflammasome components.
In this newborn mouse lung hypoxia-reoxygenation model, we found downregulation of genes of mediators of inflammation, an antiapoptotic gene expression pattern, and downregulation of DNA glycosylases. Sod1 (显示 SOD1 抗体) and Il1b were significantly differentially expressed when comparing reoxygenation using 60% O2 with air.
Report direct role of pleural cells in the pathogenesis of bleomycin-induced pulmonary fibrosis via caspase-1 (显示 CASP1 抗体)/IL-1beta pathway.
the senescence associated secretory phenotype was also increased significantly in the kidney of Sod1 (显示 SOD1 抗体)(-/)(-) mice compared to WT mice as measured by the expression of transcripts for IL-6 (显示 IL6 抗体) and IL-1b
These studies elucidate an important role for neutrophils and IL-1beta in lung carcinogenesis.
PLCd1 (显示 PLCD1 抗体) negatively regulates lipopolysaccharide-induced production of IL-1b and Fc gamma receptor (显示 FCGR1A 抗体)-mediated phagocytosis in macrophages.
these data are the first to show dramatic posttranscriptional control of inflammatory cytokine production by a relevant tissue-derived macrophage population and proteasomal degradation of proIL-1beta and NLRP3 (显示 NLRP3 抗体) as a mechanism to control inflammasome activation
data provide evidence that the NLRC4 (显示 NLRC4 抗体) inflammasome contributes to resistance through regulation of caspase-1 (显示 CASP1 抗体), IL-1beta and IL-18 (显示 IL18 抗体) in a CD11blowLy6Glow population of cells
Effects of pro-inflammatory cytokines, lipopolysaccharide and COX-2 (显示 COX2 抗体) mediators on human colonic neuromuscular function and epithelial permeability
Levels of IL-1beta and TNF-alpha (显示 TNF 抗体) in conjunctival biopsy specimens were increased in diabetic patients with dry eye
Serum and seminal levels of TNF-alpha (显示 TNF 抗体), IL-1beta, IL6 (显示 IL6 抗体) and IL8 (显示 IL8 抗体) were all significantly increased in the metabolic syndrome group.
sickle red blood cell induced TLR9 (显示 TLR9 抗体), NLRP3 (显示 NLRP3 抗体), Caspase-1 (显示 CASP1 抗体), IL-1beta and IL-18 (显示 IL18 抗体) expression and induced IL-1beta, LTB4 (显示 PTGR1 抗体) and nitrite production in PBMC cultures.
Reconstitution of ST2 (显示 SULT2A1 抗体) (IL-1R4) specific for IL-33 (显示 IL33 抗体) activity; no suppression by IL-1Ra (显示 IL1RN 抗体) though a common chain IL-1R3 (IL-1RAcP (显示 IL1RAP 抗体)) shared with IL-1 (显示 IL1A 抗体).
All the tested TLRAs induced greater infant IFN-alpha2 (显示 IFNA2 抗体) production compared to newborn and adult blood. In contrast, CpG induced greater IFN-gamma (显示 IFNG 抗体), IL-1beta, IL-4 (显示 IL4 抗体), IL-12p40, IL-10 (显示 IL10 抗体) and CXCL8 (显示 IL8 抗体) in newborn than in infant and adult blood.
SNPs in IL1B were associated with keratoconus in Chinese Han patients.
this study shows decreased expression of IL-1b in schizophrenia and bipolar patients
The results confirm that IL1B rs1143633 and rs16944 SNPs are negatively associated with post-traumatic stress disorder (PTSD) regarding them as protective variants for this disease.
the IL-1 (显示 IL1A 抗体) receptor is translocated to lipid rafts where receptor endocytosis occurs to enable the internalization-dependent IL-1 (显示 IL1A 抗体) signaling to activate the IL-1 (显示 IL1A 抗体)-induced gene expression.
This study showed that classical swine fever virus and p7 protein induced IL-1beta secretion and that p7 protein was a short-lived protein degraded by the proteasome.
local expression of IL-1beta and IL-8 (显示 IL8 抗体) in non-bacterial thrombotic endocarditis, Staphylococcus aureus infective endocarditis, animals with S. aureus sepsis without endocarditis and controls
IL1B regulates expression of IL1R1 (显示 IL1RN 抗体) and IL1RAP (显示 IL1RAP 抗体) and stimulates expression of PTGS1 (显示 PTGS1 抗体) and PTGS2 (显示 PTGS2 抗体) that are considered to be the most rate-limiting enzymes for endometrial synthesis of prostaglandins during the peri (显示 PLIN1 抗体)-implantation period of pregnancy in pigs.
the results presented here strongly suggest IL-1beta as a key molecule guiding tissue remodelling events after myocardial infarction.
The presence of embryos increased endometrial IL1B protein locally, while no differences regarding IL1R1 (显示 IL1RN 抗体) protein and IL1B and IL1R1 (显示 IL1RN 抗体) mRNA were detected.
For the inflammasome-dependent IL-1beta release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor (显示 P2RX7 抗体).
Role of TGF-beta1 (显示 TGFB1 抗体) and TNF-alpha (显示 TNF 抗体) in IL-1beta mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.
Testicular IL-1 alpha (显示 IL1A 抗体) and IL-1 beta concentrations were highest in the early post-natal period; however, IL-1 (显示 IL1A 抗体) bioactivity and IL-6 (显示 IL6 抗体) concentrations were greatest in the immediate pre-pubertal period.
Data describe the expression of IL-8, IL-1beta and their respective receptors, CXCR1 and IL-1R1 in bovine theca cells, and suggest that VEGF is associated with the IL system in theca cells in ovary.
Genes for IL-1alpha and IL-1beta are expressed and a functional IL-1R is present in bovine corpora lutea throughout luteal phase. IL-1alpha and IL-1beta may have different roles as regulating PGF (显示 PGF 抗体)(2alpha) and PGE (显示 LIPF 抗体)(2) production during luteal phase.
non-metalloproteinase mechanisms participate in IL-1 (显示 IL1A 抗体)-induced matrix degradation and loss of tissue material properties
dynamic compression stimulates cell proliferation and proteoglycan (显示 Vcan 抗体) synthesis in the presence of IL-1beta and/or inhibitors of the MAPKs and NFkappaB and AP-1 (显示 JUN 抗体) signalling pathways
These results indicate that activation of the intrinsic antistaphylococcal response in bovine endothelial cells (BEC), enhanced by TNF-alpha (显示 TNF 抗体) and IL-1beta, is effective to eliminate S. aureus and S. epidermidis.
the low friction of articular cartilage can be modified by TGF-beta1 (显示 TGFB1 抗体) and IL-1beta treatment and that the friction coefficient depends on multiple factors, including superficial zone protein localization and surface roughness
Mild heat shock increased the production of inflammatory cytokines, IL-1beta and IL-6 (显示 IL6 抗体) in rabbit cornea cells.
IL-1beta and TNF-alpha (显示 TNF 抗体) expression increases significantly during acute lung injury. Ambroxol combined with low-dose heparin inhibits teh release of IL-1beta and TNF-alpha (显示 TNF 抗体).
IL-1beta induced a significant reduction in the relative intrinsic activity of GLUT5 (显示 SLC2A5 抗体) and in this decrease are involved NO signal pathways; blockage of D-fructose intestinal uptake by IL-1beta may play an essential role in the pathophysiology of septic shock.
The inhibitory effect of IL-1beta on D-galactose absorption across mucosal side of enterocyte could be mediated by the activation of several kinases and nuclear factor kappa B.
Glucosamine hydrochloride treatment can can partially decrease the expression levels of IL-1 beta and increase the expression levels of TGF-beta 1 (显示 TGFB1 抗体), which delays the development of osteoarthritis.
In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of IL1B transcripts depending on luteal stage.
results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta,COX-2 (显示 COX2 抗体), and TGFbeta1 (显示 TGFB1 抗体)
Increased PGE2 production led to reduction in 5-LO (显示 ALOX5 抗体) products in LPS (显示 IRF6 抗体)-treated equine whole blood via IL-1b.
Results suggested that chemokine (显示 CCL1 抗体) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.
IL-1beta-induced up-regulation of matrix metalloproteinase 13 (显示 MMP13 抗体) mRNA was blocked by all concentrations of geldanamycin tested
This study examined effects of in vitro exposure to solutions of hay (显示 GTF2H5 抗体) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
, IL-1 beta
, interleukin-1 beta
, preinterleukin 1 beta
, prointerleukin-1 beta
, Interleukin-1 beta
, precursor interleukin-1beta
, interleukin-1 beta proprotein
, interleukin 1 beta
, lymphocyte proliferation-potentiating factor