Myocyte Enhancer Factor 2A (MEF2A) ELISA试剂盒产品概述

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Myocyte Enhancer Factor 2A ELISA试剂盒 (MEF2A)
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A430079H05Rik, adcad1, mef2, mef2a, rsrfc4, rsrfc9, sl2, wu:fd19d02, xmef2a

适于 Myocyte Enhancer Factor 2A 相互作用对的更多 ELISA 试剂盒

Trematode (Schistosoma mansoni) Myocyte Enhancer Factor 2A (MEF2A) interaction partners

  1. Using a dominant-negative SmMef2 mutant, authors provide evidence that SmMef2 may regulate genes in the WNT (显示 WNT2 ELISA试剂盒) pathway.

  2. The authors identify and characterize Mef2 (显示 MYEF2 ELISA试剂盒) from the schistosome worm Schistosoma mansoni (SmMef2).

Human Myocyte Enhancer Factor 2A (MEF2A) interaction partners

  1. in leiomyosarcomas (LMS), this two-faced trait of MEF2 is relevant for tumor aggressiveness. Class IIa HDACs are overexpressed in 22% of LMS, where high levels of MEF2, HDAC4 (显示 HDAC4 ELISA试剂盒) and HDAC9 (显示 HDAC9 ELISA试剂盒) inversely correlate with overall survival. The knock out of HDAC9 (显示 HDAC9 ELISA试剂盒) suppresses the transformed phenotype of LMS cells, by restoring the transcriptional proficiency of some MEF2-target loci

  2. The discovery of a novel MEF2A mutation in a Chinese family with premature CAD (显示 CAD ELISA试剂盒)/MI suggests that MEF2A may have a significant role in the pathogenesis of premature CAD (显示 CAD ELISA试剂盒)/MI.

  3. The findings of this study are consistent with MEF2A deregulation conferring risk of formal thought disorder.

  4. Variants in the 3'-UTR of MEF2A are associated with coronary artery disease in a Chinese Han population.

  5. p38 MAPK (显示 MAPK14 ELISA试剂盒) is a key regulator of canonical Wnt (显示 WNT2 ELISA试剂盒) signaling by promoting a phospho-dependent interaction between MEF2 and beta-catenin (显示 CTNNB1 ELISA试剂盒) to enhance cooperative transcriptional activity and cell proliferation.

  6. Mechanistically, MEF-2 (显示 MYEF2 ELISA试剂盒) was recruited to the viral promoter (LTR, long terminal repeat) in the context of chromatin, and constituted Tax (显示 CNTN2 ELISA试剂盒)/CREB (显示 CREB1 ELISA试剂盒) transcriptional complex via direct binding to the HTLV-1 LTR.

  7. Our results revealed a link and interaction between MEF2A and miR (显示 MLXIP ELISA试剂盒)-143 and suggested a potential mechanism for MEF2A to regulate H(2)O(2) -induced VSMC senescence.

  8. six or seven amino acid deletions and synonymous mutations (147143G-->A)in exon 11 of the MEF2A gene may be correlated with susceptibility to coronary artery disease in the Chinese population

  9. MEF2A is targeted to lysosomes for chaperone-mediated autophagy degradation; oxidative stress-induced (显示 SQSTM1 ELISA试剂盒) lysosome destabilization leads to the disruption of MEF2A degradation as well as the dysregulation of its function

  10. MEF2 transcription factors promotes epithelial-mesenchymal transition and invasiveness of hepatocellular carcinoma through TGF-beta1 (显示 TGFB1 ELISA试剂盒) autoregulation circuitry.

Mouse (Murine) Myocyte Enhancer Factor 2A (MEF2A) interaction partners

  1. these data indicate that MEF2 (显示 MEF2C ELISA试剂盒) and AP-1 (显示 JUN ELISA试剂盒) confer antagonistic regulation of Hspb7 (显示 HSPB7 ELISA试剂盒) gene expression in skeletal muscle, with implications for autophagy and muscle atrophy.

  2. Nuclear HDAC4 (显示 HDAC5 ELISA试剂盒) binds to chromatin as well as to MEF2A transcription factor, leading to histone deacetylation and altered neuronal gene expression. By using a Cdkl5 (显示 CDKL5 ELISA试剂盒) knockout (Cdkl5 (显示 CDKL5 ELISA试剂盒) -/Y) mouse model, we found that hypophosphorylated HDAC4 (显示 HDAC5 ELISA试剂盒) translocates to the nucleus of neural precursor cells, thereby reducing histone 3 acetylation.

  3. Knockdown of MEF2A significantly reduced hyperglycemia-induced cardiac fibroblast proliferation and migration, myofibroblast differentiation, matrix metalloproteinase (显示 MMP20 PLURAL_@17599@) activities, and collagen production.

  4. Lentivirus-mediated MEF 2A shRNA accelerates inflammation and atherosclerosis in APOE (显示 APOE ELISA试剂盒) knockout mice, but has no effect on lipoprotein levels in plasma.

  5. microRNAs encoded by the Gtl2-Dio3 (显示 DIO3 ELISA试剂盒) noncoding RNA locus function downstream of the MEF2A

  6. Our results indicated that exercise-induced CPT1b (显示 CPT1B ELISA试剂盒) expression was at least in part mediated by HDAC5 (显示 HDAC5 ELISA试剂盒)/MEF2A interaction.

  7. MEF2A is targeted to lysosomes for chaperone-mediated autophagy degradation; oxidative stress-induced (显示 SQSTM1 ELISA试剂盒) lysosome destabilization leads to the disruption of MEF2A degradation as well as the dysregulation of its function

  8. Whereas MEF2A is absolutely required for proper myoblast differentiation, MEF2B (显示 MEF2B ELISA试剂盒), -C, and -D were found to be dispensable for this process.

  9. A role for endogenous MEF2 (显示 MEF2C ELISA试剂盒) factors exclusively in hormone/Fsk/cAMP-induced Nr4a1 (显示 NR4A1 ELISA试剂盒) gene expression in mouse MA-10 Leydig cells.

  10. Combined deletion of the Mef2a, c, and d genes results in a blockade to muscle regeneration.

Xenopus laevis Myocyte Enhancer Factor 2A (MEF2A) interaction partners

  1. These results show that NLK specifically regulates the MEF2A activity required for anterior formation in Xenopus development.

Cow (Bovine) Myocyte Enhancer Factor 2A (MEF2A) interaction partners

  1. polymorphisms in the bovine MEF2A gene and their effect on the MEF2A mRNA expression level in the longissimus dorsi muscle

Zebrafish Myocyte Enhancer Factor 2A (MEF2A) interaction partners

  1. Mef2 (显示 MYEF2 ELISA试剂盒) controls skeletal muscle formation after terminal differentiation.

  2. Results suggest that myocyte-specific enhancer factor 2A is essential for cardiac contractility

  3. Results suggest that myocyte enhancer factor 2A is essential for zebrafish posterior somite development.

Myocyte Enhancer Factor 2A (MEF2A) 抗原简介

Antigen Summary

The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Myocyte Enhancer Factor 2A (MEF2A)

  • myocyte enhancer factor 2A (MEF2A) Elisa Kit
  • myocyte-specific enhancer factor 2A (EDI_092490) Elisa Kit
  • myocyte-specific enhancer factor 2A (EDI_038250) Elisa Kit
  • myocyte-specific enhancer factor 2a (Smp_161530) Elisa Kit
  • myocyte-specific enhancer factor 2a (Smp_129430) Elisa Kit
  • myocyte enhancer factor 2A (mef2a) Elisa Kit
  • myocyte enhancer factor 2A (Mef2a) Elisa Kit
  • myocyte enhancer factor 2a (Mef2a) Elisa Kit
  • myocyte enhancer factor 2aa (mef2aa) Elisa Kit
  • A430079H05Rik Elisa Kit
  • adcad1 Elisa Kit
  • mef2 Elisa Kit
  • mef2a Elisa Kit
  • rsrfc4 Elisa Kit
  • rsrfc9 Elisa Kit
  • sl2 Elisa Kit
  • wu:fd19d02 Elisa Kit
  • xmef2a Elisa Kit

Protein level used designations for MEF2A

myocyte-specific enhancer factor 2A , myocyte-specific enhancer factor 2a , myocyte enhancer factor 2A , MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) , myocyte-specific enhancer factor 2A-like , myocyte-specific enhancer factor 2A homolog , serum response factor-like protein 1 , SL-2 , XMEF2A1 , serum response factor-like protein 2 , xMEF2A , etID309779.18 , myocyte enhancer factor 2a

GENE ID SPECIES
100050068 Equus caballus
5881199 Entamoeba dispar SAW760
5883634 Entamoeba dispar SAW760
8341405 Schistosoma mansoni
8345426 Schistosoma mansoni
100171617 Pongo abelii
453680 Pan troglodytes
708956 Macaca mulatta
100216045 Xenopus (Silurana) tropicalis
100399429 Callithrix jacchus
100555625 Anolis carolinensis
100589007 Nomascus leucogenys
4205 Homo sapiens
17258 Mus musculus
309957 Rattus norvegicus
395670 Gallus gallus
479021 Canis lupus familiaris
100037273 Sus scrofa
100339777 Oryctolagus cuniculus
380452 Xenopus laevis
407231 Bos taurus
30564 Danio rerio
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