Arhgef9 (Arhgef9) ELISA试剂盒产品概述

Full name:
Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 ELISA试剂盒 (Arhgef9)
在www.antibodies-online.cn可供0 Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9) ELISA试剂盒的不同的供货商。 再加上,我们可以发Arhgef9 抗体 (55)Arhgef9 蛋白 (5)和数多这个蛋白质的别的产品。 总共65 Arhgef9产品已列进来了。
别名:
9630036L12Rik, A230067K14, ARHGEF9, COLLYBISTIN, EIEE8, HPEM-2, mKIAA0424, PEM-2, PEM2, wu:fj33b10
list all ELISA KIts 基因 基因ID UniProt
 Arhgef9 Arhgef9 23229 O43307
大鼠 Arhgef9 Arhgef9 66013 Q9QX73
小鼠 Arhgef9 Arhgef9 236915 Q3UTH8

显示所有的同义词

适于 Arhgef9 相互作用对的更多 ELISA 试剂盒

Human Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9) interaction partners

  1. Autism spectrum disorder patient with the smallest inactivating deletion in the collybistin gene.

  2. Collybistin forms a complex with mTOR (显示 FRAP1 ELISA试剂盒) and eIF3 (显示 EIF3A ELISA试剂盒) and by sequestering these proteins downregulates mTORC1 signaling and protein synthesis potentially contributing to intellectual disability and autism.

  3. Impairment of the membrane lipid binding activity of Collybistin R290H and a consequent defect in inhibitory synapse maturation represent a likely molecular pathomechanism of epilepsy and mental retardation in humans.

  4. The enhancement of Cb-induced gephyrin (显示 GPHN ELISA试剂盒) clustering by GTP (显示 AK3 ELISA试剂盒)-TC10 (显示 RHOQ ELISA试剂盒) does not depend on the guanine nucleotide exchange activity of Cb but involves an interaction that resembles reported interactions of other small GTPases with their effectors

  5. Phosphorylation of gephyrin (显示 GPHN ELISA试剂盒) in hippocampal neurons by cyclin-dependent kinase (显示 CDK1 ELISA试剂盒) CDK5 (显示 CDK5 ELISA试剂盒) at Ser (显示 SIGLEC1 ELISA试剂盒)-270 is dependent on collybistin.

  6. Data indicate that ARHGEF9 is likely to be responsible for syndromic X-linked mental retardation associated with epilepsy.

  7. These results reveal that G(s) and G(q) signalings regulate hPEM-2 functions through PKA and c-Src (显示 SRC ELISA试剂盒) in Neuro-2a neuroblastoma (显示 ARHGEF16 ELISA试剂盒) cells, respectively.

  8. major regulator of GABAergic postsynaptic gephyrin (显示 GPHN ELISA试剂盒) clustering

  9. Study propose that the collybistin-gephyrin (显示 GPHN ELISA试剂盒) complex has an intimate role in the clustering of GABA(A)Rs containing the alpha2 subunit.

  10. Here we identified residues critical for interaction with gephyrin (显示 GPHN ELISA试剂盒) in the linker region between the SH3 and the DH domains of collybistin.

Mouse (Murine) Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9) interaction partners

  1. Within this network, collybistin can adopt open/active and closed/inactive conformations to act as a switchable adaptor that links gephyrin (显示 GPHN ELISA试剂盒) to plasma membrane phosphoinositides.

  2. data show that collybistin co-clusters with gephyrin (显示 GPHN ELISA试剂盒) and GABA(A) Rs in synaptic puncta and is recruited to postsynaptic specializations early during synapse development; it co-localizes with GABA(A) Rs containing the alpha1, alpha2, or alpha3 subunits

  3. The results of this study provided evidence that the formation of gephyrin (显示 GPHN ELISA试剂盒) scaffolds at inhibitory synapses requires an intact Cb II PH-domain but is Cdc42 (显示 CDC42 ELISA试剂盒)-independent.

  4. The resolution crystal structure of the Cdc42 (显示 CDC42 ELISA试剂盒)-collybistin II complex reveals a novel conformation of the switch I region of Cdc42 (显示 CDC42 ELISA试剂盒), and biochemical data indicate that gephyrin (显示 GPHN ELISA试剂盒) negatively regulates collybistin activity.

  5. Cb is essential for gephyrin (显示 GPHN ELISA试剂盒)-dependent clustering of a specific set of GABA(A) receptors, but not required for glycine receptor (显示 GLRB ELISA试剂盒) postsynaptic localization.

  6. Data provide the first evidence that collybistin deficiency leads to significant changes of GABAergic inhibition, network excitability and synaptic plasticity in vivo.

Arhgef9 抗原简介

Antigen Summary

The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Arhgef9

  • Cdc42 guanine nucleotide exchange factor (GEF) 9 (ARHGEF9) Elisa Kit
  • Cdc42 guanine nucleotide exchange factor (GEF) 9b (arhgef9b) Elisa Kit
  • Cdc42 guanine nucleotide exchange factor (GEF) 9 (arhgef9) Elisa Kit
  • Cdc42 guanine nucleotide exchange factor (GEF) 9 (Arhgef9) Elisa Kit
  • CDC42 guanine nucleotide exchange factor (GEF) 9 (Arhgef9) Elisa Kit
  • rho guanine nucleotide exchange factor 9-like (LOC537718) Elisa Kit
  • 9630036L12Rik Elisa Kit
  • A230067K14 Elisa Kit
  • ARHGEF9 Elisa Kit
  • COLLYBISTIN Elisa Kit
  • EIEE8 Elisa Kit
  • HPEM-2 Elisa Kit
  • mKIAA0424 Elisa Kit
  • PEM-2 Elisa Kit
  • PEM2 Elisa Kit
  • wu:fj33b10 Elisa Kit

Protein level used designations for Arhgef9

Cdc42 guanine nucleotide exchange factor (GEF) 9 , Cdc42 guanine nucleotide exchange factor 9 , Cdc42 guanine exchange factor 9 , rho guanine nucleotide exchange factor 9-like , PEM-2 homolog , hPEM-2 collybistin , rac/Cdc42 guanine nucleotide exchange factor 9 , rho guanine nucleotide exchange factor 9 , collybistin I , collybistin

GENE ID SPECIES
422315 Gallus gallus
465666 Pan troglodytes
560923 Danio rerio
100018406 Monodelphis domestica
100054217 Equus caballus
100125033 Xenopus (Silurana) tropicalis
100338091 Oryctolagus cuniculus
100393157 Callithrix jacchus
100512575 Sus scrofa
100586595 Nomascus leucogenys
23229 Homo sapiens
66013 Rattus norvegicus
236915 Mus musculus
100171927 Pongo abelii
537718 Bos taurus
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