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UCP2 抗体

(Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [provided by RefSeq, Jul 2008].
UCP2 抗体  (Internal Region) UCP2 抗体  (Internal Region) UCP2 抗体 (Internal Region) (ABIN5539644)

Verified UCP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

UCP2 抗体  (AA 154-289) UCP2 抗体  (AA 154-289) UCP2 抗体 (AA 154-289) (ABIN7428086)

UCP2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C12 unconjugated

UCP2 抗体  (AA 99-216) UCP2 抗体  (AA 99-216) UCP2 抗体 (AA 99-216) (ABIN7435031)

UCP2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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Find UCP2 抗体 for a variety of species such as anti-Human UCP2, anti-Mouse UCP2, anti-Rat UCP2. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular UCP2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF
Validations
  • (7)
Cat. No. ABIN5539644
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7428086
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7435031
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, ICC, FACS
Validations
  • (5)
Cat. No. ABIN5542465
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro)
Validations
  • (2)
  • (2)
Cat. No. ABIN675428
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, ICC, FACS
Validations
  • (3)
Cat. No. ABIN5542464
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (4)
Cat. No. ABIN1175758
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC
Validations
  • (4)
Cat. No. ABIN1175761
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7244378
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ICC, IF
Validations
  • (3)
Cat. No. ABIN7043873
Quantity 25 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (1)
Cat. No. ABIN7159951
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN521239
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN521237
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
  • (1)
Cat. No. ABIN5518965
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF (cc), IF (p), ICC, IHC (p), IHC (fro)
Validations
Cat. No. ABIN6945251
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our UCP2 抗体

Bo, Xie, Guo, Zhang, Guan, Li, Lu, Meng: "Methylglyoxal Impairs Insulin Secretion of Pancreatic β-Cells through Increased Production of ROS and Mitochondrial Dysfunction Mediated by Upregulation of UCP2 and MAPKs." in: Journal of diabetes research, Vol. 2016, pp. 2029854, (2016) (PubMed).

Kim, Hong, Kim, Kim, Jang, Leem, Park, Lee, Koh: "S-adenosyl methionine prevents endothelial dysfunction by inducing heme oxygenase-1 in vascular endothelial cells." in: Molecules and cells, Vol. 36, Issue 4, pp. 376-84, (2014) (PubMed).

Liu, Shim, Nguyen, Gibbons, Mitchell, Poirier: "Tempol protects cardiomyocytes from nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 139, Issue 1, pp. 133-41, (2014) (PubMed).

Dando, Fiorini, Pozza, Padroni, Costanzo, Palmieri, Donadelli: "UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells." in: Biochimica et biophysica acta, Vol. 1833, Issue 3, pp. 672-9, (2013) (PubMed).

Vázquez-Medina, Popovich, Thorwald, Viscarra, Rodriguez, Sonanez-Organis, Lam, Peti-Peterdi, Nakano, Nishiyama, Ortiz: "Angiotensin receptor-mediated oxidative stress is associated with impaired cardiac redox signaling and mitochondrial function in insulin-resistant rats." in: American journal of physiology. Heart and circulatory physiology, Vol. 305, Issue 4, pp. H599-607, (2013) (PubMed).

Liu, He, Li: "Exhaustive training increases uncoupling protein 2 expression and decreases Bcl-2/Bax ratio in rat skeletal muscle." in: Oxidative medicine and cellular longevity, Vol. 2013, pp. 780719, (2013) (PubMed).

Chuang, Lin, Huang, Chang, Liou, Chen, Chang, Chan et al.: "Peroxisome proliferator-activated receptors ?/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status ..." in: Journal of neuroinflammation, Vol. 9, pp. 184, (2012) (PubMed).

Montez, Vázquez-Medina, Rodríguez, Thorwald, Viscarra, Lam, Peti-Peterdi, Nakano, Nishiyama, Ortiz: "Angiotensin receptor blockade recovers hepatic UCP2 expression and aconitase and SDH activities and ameliorates hepatic oxidative damage in insulin resistant rats." in: Endocrinology, Vol. 153, Issue 12, pp. 5746-59, (2012) (PubMed).

De Souza, Araújo, Stoppiglia, Pauli, Ropelle, Rocco, Marin, Franchini, Carvalheira, Saad, Boschero, Carneiro, Velloso: "Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 4, pp. 1153-63, (2007) (PubMed).

Aliases for UCP2 抗体

mitochondrial uncoupling protein 2 (PTRG_09289) 抗体
uncoupling protein 2 (UCP2) 抗体
mitochondrial uncoupling protein 2 (LOC100282746) 抗体
uncoupling protein 2 (mitochondrial, proton carrier) L homeolog (ucp2.L) 抗体
uncoupling protein 2 (mitochondrial, proton carrier) (ucp2) 抗体
uncoupling protein 2 (ucp2) 抗体
uncoupling protein 1 (ucp1) 抗体
uncoupling protein 2 (mitochondrial, proton carrier) (Ucp2) 抗体
uncoupling protein 2 (Ucp2) 抗体
ATUCP2 抗体
BMIQ4 抗体
cb74 抗体
DKFZp470P1633 抗体
K19M22.21 抗体
K19M22_21 抗体
MGC53319 抗体
MGC75881 抗体
SLC25A8 抗体
Slc25a8 抗体
UCP2 抗体
ucp2 抗体
UCPH 抗体
uncoupling protein 2 抗体
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