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Rat (Rattus) NOS1 ELISA Kit for Sandwich ELISA - ABIN416139
Tang, Fang, Zhou, Zhuang, Zhang, Gu, Hu: A novel mechanism of formaldehyde neurotoxicity: inhibition of hydrogen sulfide generation by promoting overproduction of nitric oxide. in PLoS ONE 2013
Human NOS1 ELISA Kit for Sandwich ELISA - ABIN414454
Yegin, Iyidir, Demirta?, Suyan?, Yetkin, Pa?ao?lu, Ilhan, Sucak: The interplay among iron metabolism, endothelium and inflammatory cascade in dysmetabolic disorders. in Journal of endocrinological investigation 2014
selected nNOS polymorphisms do not significantly contribute to Parkinson's disease risk in north Indian population.
Lysophosphatidylcholine induced nNOS uncoupling and nNOS(Ser852) phosphorylation, reduced NO and H2O2 production and improved superoxide production by modulating ERK1/2 (显示 MAPK1/3 ELISA试剂盒) activity in endothelial cells.
NOS1 (missense variant rs79487279) was associated with bipolar disorder.
Data suggest that NOS1 and NOS2 play roles in stress-induced surge in nitric oxide (NO) production; NO serves as mediator for development of secondary neurological disorders associated with stress such as anxiety and anxiety disorders. [REVIEW]
nNOS mediates the human coronary vasodilator response to mental stress, predominantly through actions at the level of coronary resistance vessels.
These findings highlight a key role of the TLR4 (显示 TLR4 ELISA试剂盒)-NOS1-AP1 (显示 FOSB ELISA试剂盒) signaling axis in regulating macrophage polarization
Association between NOS1 and PTSD severity and stress was found. NOS1 was associated with resilience.
Data show that metastasis associated 1 (MTA1 (显示 MTA1 ELISA试剂盒)) represses neuronal nitric oxide synthase (nNOS) expression upon oxygen glucose deprivation (OGD (显示 FGFR1 ELISA试剂盒))-induced oxidative stress.
Superoxide generation from NOS1 splice variants and its potential involvement in redox signal regulation has been described.
expression of neuronal NOS heterodimers in insect cells, where we take advantage of an exogenous heme-triggered chaperone-assisted assembly process, provides an approximately 43% yield in heterodimeric NOS.
In an animal model of Alzheimer's disease, nNOS dimers are disrupted in the cerebral cortex and may be involved in the decrease of nitric oxide production and the development of Alzheimer's disease.
Immunohistochemical analysis confirmed increased amount of NOS1 protein in neuronal somata and processes in the perilesional cortex in APP (显示 APP ELISA试剂盒)/PS1 (显示 PSEN1 ELISA试剂盒)-severe traumatic brain injury(TBI) mice compared to APP (显示 APP ELISA试剂盒)/PS1 (显示 PSEN1 ELISA试剂盒)-sham (p < 0.05) or Wt-sTBI mice (p < 0.01).
Ischemic postconditioning protects the heart against ischemia-reperfusion injury via the NOS1 pathway in the sarcoplasmic reticulum and mitochondria.
To investigate the role of medial ganglionic eminence-(MGE)-derived nNOS(+) interneurons in fear learning, donor MGE cells were transplanted into dentate gyrus of nNOS knock-out (nNOS(-/-)) or wild-type mice. Results showed that the transplantation of MGE cells promoted the acquisition of nNOS(-/-) but not the wild-type mice, suggesting the importance of nNOS(+) neurons in fear acquisition.
aerobic exercise training could improve cardiac systolic function and alleviate LV chamber dilation, cardiac fibrosis and hypertrophy in heart failure mice. The mechanism responsible for the protective effects of aerobic exercise is associated with the activation of the beta3-AR-nNOS-NO pathway.
These findings highlight a key role of the TLR4 (显示 TLR4 ELISA试剂盒)-NOS1-AP1 (显示 JUN ELISA试剂盒) signaling axis in regulating macrophage polarization
The findings indicate that the activation of sigma1R (显示 SIGMAR1 ELISA试剂盒) can alleviate postpartum "depression" through increasing nNOS-NO-CREB (显示 CREB1 ELISA试剂盒) activities.
To optimize a dystrophin (显示 DMD ELISA试剂盒) cDNA construct for therapeutic application we designed and produced four human minidystrophins within the packaging capacity of lentiviral vectors. Two novel minidystrophins retained the centrally located neuronal nitric oxide synthase (nNOS)-anchoring domain in order to achieve sarcolemmal nNOS restoration, which is lost in most internally deleted dystrophin (显示 DMD ELISA试剂盒) constructs.
nNOSmu is not essential for skeletal muscle glucose uptake during exercise, and the higher skeletal muscle glucose uptake during exercise in nNOSmu(-/-) mice may be due to compensatory increases in AMPK (显示 PRKAA1 ELISA试剂盒) activation.
nNOS expression levels increased with age in the hippocampus and cerebellum, but not in the cortex. Moreover, environmental enrichment reduced anxiety-like behaviors in aged mice and reduced nNOS expression levels in the cerebellum, but not in the cortex.
findings indicate that spinal transection affects nNOS and parvalbumin (显示 PVALB ELISA试剂盒) in different neuronal circuits
amyloid and oxidative stress-related disease proteins like NOS 1 is increased in expression and form localized accumulations in diabetic muscle in this rabbit model of diabetes.
Motoneurons in the ventral horns respond more sensitively to ischemia/reperfusion than do neurons localized in the other spinal cord regions. Changes in cNOS (显示 NOS3 ELISA试剂盒) activity may also influence the axonal conductance in the white matter.
Distribution pattern of the enzyme responsible for the synthesis of NO, nitric oxide synthase (显示 NOS ELISA试剂盒), in the population of primary afferent neurons of the trigeminal ganglion and mesencephalic trigeminal nucleus of the rabbit.
The regional distribution of nitric oxide synthase (显示 NOS ELISA试剂盒) activity and neuronal nitric oxide synthase immunoreactivity, measured segment by segment shows that nitric oxide may play a significant role in the stepping cycle in the quadrupeds.
NOS (显示 NOS ELISA试剂盒) via Nitric oxide production may play a neuroprotective role in ischemic/reperfusion injury.
the dynamics of glial cell line-derived neurotrophic factor (gdnf) and nitric oxide synthases (nos) mRNA expression in various regions of zebrafish brain
NOS1 is a key regulator of motor axon ontogeny in the developing vertebrate spinal cord.
The distribution pattern of nNOS gene expression showed the highest expression levels in the forebrain followed by the optic tectum, the brainstem and the spinal cord, whereas scarce expression was detected in the cerebellum.
glutamate (显示 GRIN2A ELISA试剂盒)-induced apoptosis was strongly reversed by nNOS inhibitors and weakly by iNOS (显示 NOS2 ELISA试剂盒) inhibitors, thus indicating nNOS involvement in glutamate (显示 GRIN2A ELISA试剂盒)-mediated apoptosis.
The expression, localization, and distribution of 3 nitric oxide synthase (显示 NOS ELISA试剂盒) enzymes through the estrous cycle in bovien fallopian tubes are reported.
Lys842 in neuronal nitric-oxide synthase enables the autoinhibitory insert to antagonize calmodulin (显示 KRIT1 ELISA试剂盒) binding, increase FMN (显示 FMN1 ELISA试剂盒) shielding, and suppress interflavin electron transfer
This study demonstrated for the first time a strong expression of NGF, TrkA, CGRP, nNOS and neuronal specific enolase in the majority of esophageal enteric nervous system components.
Our results suggest that the presence of low mycotoxin doses in feed slows down the mRNA expression of nitric oxide synthase-1 and nitric oxide synthase-2 genes which probably lowers the concentrations of nitric oxide, a common precursor of inflammation.
nNOS is an important regulator of renal hemodynamics in the newborn kidney, but not in the adult.
Data suggest that pig sperm contain bNOS, iNOS (显示 NOS2 ELISA试剂盒), and eNOS (显示 NOS3 ELISA试剂盒); up-regulation of NOS (显示 NOS ELISA试剂盒) by leptin (显示 LEP ELISA试剂盒) during acrosome reaction and inhibition of acrosome reaction by inhibitors of nitric oxide synthases suggests these enzymes are involved in acrosome reaction.
Periodic acceleration (pGz) acutely increases endothelial and neuronal nitric oxide synthase expression in endomyocardium of normal swine.
Regional difference in blood flow has no effect on nNOS protein content in different sized conduit arteries.
study concludes that in the cerebral cortex of newborn piglets, the mechanism of hypoxia-induced increased tyrosine phosphorylation of nNOS is mediated by nNOS-derived nitric oxide.
Data suggest that angiotensin II regulates nNOS and eNOS (显示 NOS3 ELISA试剂盒) expression and NOS (显示 NOS ELISA试剂盒) activity in afferent arterioles of the developing kidney via angiotensin 1 and 2 receptors.
form-deprivation myopia upregulates the expression of NMDAR1 (显示 GRIN1 ELISA试剂盒) and ncNOS and increases cGMP content in the retina. NMDAR1 (显示 GRIN1 ELISA试剂盒)/NO-cGMP pathway may contribute to abnormal visual signals during myopic progression.
The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.
NOS type I
, constitutive NOS
, neuronal NOS
, nitric oxide synthase, brain
, peptidyl-cysteine S-nitrosylase NOS1
, nitric oxidase synthase
, neuronal nitric oxide synthase
, nitric oxide synthase 1 (neuronal)
, Nitric oxide synthase, brain
, neuronal nitric oxide synthase 1
, nitric oxide synthase 1 L homeolog
, LOW QUALITY PROTEIN: nitric oxide synthase, brain