Use your antibodies-online credentials, if available.
the successful purification of functionally intact Gbeta5 (显示 GNB5 ELISA试剂盒)-free recombinant RGS11 was reported that differentially interact with R7BP (显示 RGS7BP ELISA试剂盒) and Galpha (显示 SUCLG1 ELISA试剂盒)(oa).
RGS7 (显示 RGS7 ELISA试剂盒) and RGS11 are the key GTPase (显示 RACGAP1 ELISA试剂盒) accelerating proteins in the mGluR6 (显示 GRM6 ELISA试剂盒) pathway of retinal rod ON bipolar cells that set the sensitivity and time course of light-evoked responses.
Defective retinal depolarizing bipolar cells in regulators of G protein signaling (RGS) 7 (显示 RGS7 ELISA试剂盒) and 11 double null mice.
Identification and characterization of alternatively spliced murine Rgs11 isoforms: genomic structure and gene analysis
RGS11 staining is present in dendritic tips of rod ON-retinal bipolar cell and cone ON-retinal bipolar cell. Genetic disruption of RGS11 produced delays in the ON-BPC-derived electroretinogram b-wave, but no changes in the photoreceptor-derived a-wave.
The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
regulator of G-protein signalling 11
, regulator of G-protein signalling 9