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Grsf1 controls translation of the protein Use1, possibly by positioning the 40S ribosomal subunit and associated translation factors in front of the translation start site.
Uba6 (显示 UBA6 ELISA试剂盒) and Use1 (显示 UBE2Z ELISA试剂盒) promote proteasomal turnover of Ube3a (显示 ube3a ELISA试剂盒) in mouse embryo fibroblasts (MEFs) and catalyze Ube3a (显示 ube3a ELISA试剂盒) ubiquitylation in vitro.
Domain analyses of Sec22b revealed that the R-SNARE motif, a selective domain for forming a SNARE complex with syntaxin18 and/or D12, was responsible for the inhibition of phagocytosis.
p31 (显示 ATP6V1E1 ELISA试剂盒) is an essential molecule involved in the maintenance of endoplasmic reticulum (ER) morphology and that its deficiency leads to ER stress-induced apoptosis.
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.
, embryonic development factor 2
, vesicle transport protein USE1
, 26S proteasome non-ATPase regulatory subunit 8
, 26S proteasome regulatory subunit RPN12
, 26S proteasome regulatory subunit S14
, 26S proteasome regulatory subunit p31
, ATPase, H+ transporting, V1 subunit E
, ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E
, V-ATPase subunit E 1
, V-type proton ATPase subunit E 1
, VATPase, H+ transporting, lysosomal V1 subunit E1
, vacuolar H(+)-ATPase, E subunit
, vacuolar H+ ATPase E1
, vacuolar proton pump subunit E 1
, proteasome 26S non-ATPase subunit 8 b
, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 b
, proteasome 26S non-ATPase subunit 8
, proteasome 26S subunit, non-ATPase, 8
, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 a
, proteasome 26S non-ATPase subunit 8 a
, proteasome (prosome, macropain) 26S subunit, non-ATPase, 8