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抗Rat (Rattus) 抗体:
Caenorhabditis elegans (C. elegans) Monoclonal PSMD11 Primary Antibody for ELISA, WB - ABIN450004
Vilchez, Morantte, Liu, Douglas, Merkwirth, Rodrigues, Manning, Dillin: RPN-6 determines C. elegans longevity under proteotoxic stress conditions. in Nature 2012
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Human Polyclonal PSMD11 Primary Antibody for IP, WB - ABIN4348274
Welk, Coux, Kleene, Abeza, Trümbach, Eickelberg, Meiners: Inhibition of Proteasome Activity Induces Formation of Alternative Proteasome Complexes. in The Journal of biological chemistry 2016
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Cow (Bovine) Polyclonal PSMD11 Primary Antibody for WB - ABIN2779581
Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007
Data show that activated PKA phosphorylates the 19S subunit, Rpn6/PSMD11 (regulatory particle non-ATPase 6 (显示 MT-ATP6 抗体)/proteasome subunit D11) at Ser14.
human embryonic stem cells (hESCs) exhibit high proteasome activity that is correlated with increased levels of the 19S proteasome subunit PSMD11 (known as RPN-6 in Caenorhabditis elegans) and a corresponding increased assembly of the 26S/30S proteasome
AMP-activated protein kinase (显示 PRKAA2 抗体) is able to interact physically with this subunit and modify its phosphorylation status.
interaction with ubiquitinated NF-kappaB2/p100 (显示 CUX1 抗体)
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene.
proteasome 26S non-ATPase subunit 11
, 26S proteasome non-ATPase regulatory subunit 11B
, 26S proteasome regulatory subunit RPN6-B
, proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
, 26S proteasome non-ATPase regulatory subunit 11
, 26S proteasome regulatory subunit 9
, 26S proteasome regulatory subunit RPN6
, 26S proteasome regulatory subunit S9
, 26S proteasome regulatory subunit p44.5