anti-MAX (MAX) 抗体产品概述

Full name:
anti-Max Protein 抗体 (MAX)
在www.antibodies-online.cn可供30 Max Protein (MAX) 抗体的1不同的供货商。 再加上,我们可以发和数多这个蛋白质的别的产品。 总共36 MAX产品已列进来了。
别名:
AA960152, AI875693, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8

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抗Mouse (Murine) MAX 抗体:

抗Human MAX 抗体:

抗Rat (Rattus) MAX 抗体:

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更多抗MAX的相互作用对抗体

Mouse (Murine) Max Protein (MAX) interaction partners

  1. Studies suggest that inducible MYC Associated Factor X (MAX) knockout embryonic stem cells (ESCs (显示 NR2E3 抗体)) provide an excellent platform for exploring the molecular mechanisms of meiosis initiation.

  2. Myc (显示 MYC 抗体) represses C/EBPdelta (显示 CEBPD 抗体) expression by associating with the C/EBPdelta (显示 CEBPD 抗体) proximal promoter as a transient component of a repressive complex that includes Max and Miz1 (显示 PIAS2 抗体)

  3. The switch from Mnt (显示 MNT 抗体)-Max to Myc (显示 MYC 抗体)-Max during bile duct ligation (cholestasis) and in hepatocytes treated with lithocholic acid is responsible for the induction in p53 (显示 TP53 抗体) and cyclin D1 (显示 CCND1 抗体) expression and contributes to apoptosis.

  4. the c-Myc (显示 MYC 抗体)-Max complex exerts its transcriptional regulatory role and hnRNP U (显示 HNRNPU 抗体) may be a coactivator of this transcriptional activator complex.

Human Max Protein (MAX) interaction partners

  1. Sequence-specific DNA binding by MYC (显示 MYC 抗体)/MAX to low-affinity non-E-box motifs

  2. The SDHA (显示 SDHA 抗体), TMEM127 (显示 TMEM127 抗体), MAX, and SDHAF2 (显示 Sdhaf2 抗体) genes contribute to hereditary pheochromocytoma and paraganglioma.

  3. These results suggest that the wild type Max homodimer is important for attenuating the binding of c-Myc (显示 MYC 抗体) to specific and non-specific DNA, whereas alternative splicing (e.g. DeltaMax) is unable to do so. Conversely, the splicing of Max into DeltaMax could provoke an increase in overall chromatin bound c-Myc (显示 MYC 抗体).

  4. The mechanism of inhibition of c-Myc (显示 MYC 抗体) transcriptional activity by Miz-1 (显示 ZBTB17 抗体) that binds c-Myc (显示 MYC 抗体) while competing for binding with Max has been described.

  5. The introduction of wild-type MAX cDNA into PC12 cells significantly decreased MYC's ability to bind to canonical E-boxes, while pathogenic MAX proteins were not able to fully repress MYC (显示 MYC 抗体) activity. Further clinical and molecular evaluation of variant carriers corroborated the results obtained with the functional assessment.

  6. Celastrol and some of its quinone methidecontaining analogs directly inhibit c-Myc (显示 MYC 抗体)-Max heterodimers in tumor cells.

  7. We confirmed that these dimeric inhibitors directly bind to Myc (显示 MYC 抗体) blocking its interaction with Max and affect transcription of MYC (显示 MYC 抗体) dependent genes.

  8. MYC (显示 MYC 抗体) is part of a network of bHLHLZ proteins centered on the MYC (显示 MYC 抗体) heterodimeric partner MAX and its counterpart, the MAX-like protein MLX (显示 MLX 抗体).

  9. Myc (显示 MYC 抗体) and its obligate heterodimeric partner, Max, are integral to the coordinated recruitment and post-translational modification of components of the core transcriptional machinery.

  10. Here we review the activities of MYC (显示 MYC 抗体), MNT (显示 MNT 抗体) and other MAX interacting proteins in the setting of T and B cell activation (显示 BLNK 抗体) and oncogenesis

MAX 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with MAX

  • Max protein (Max) 抗体
  • MYC associated factor X (MAX) 抗体
  • MYC associated factor X (Max) 抗体
  • AA960152 抗体
  • AI875693 抗体
  • bHLHd4 抗体
  • bHLHd5 抗体
  • bHLHd6 抗体
  • bHLHd7 抗体
  • bHLHd8 抗体

Protein level used designations for anti-Max Protein (MAX) 抗体

myc-associated factor X , myc-binding novel HLH/LZ protein , protein max , protein myn , class D basic helix-loop-helix protein 4

GENE ID SPECIES
17187 Mus musculus
100858676 Gallus gallus
4149 Homo sapiens
540616 Bos taurus
60661 Rattus norvegicus
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