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Ras Homolog Gene Family, Member A 抗体

(Ras Homolog Gene Family, Member A (RHOA))
Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA- DIAPH1 signaling pathway plays an important role in ERBB2- dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
RHOA 抗体  (AA 1-193) RHOA 抗体  (AA 1-193) RHOA 抗体 (AA 1-193) (ABIN559931)

RHOA 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1B12 unconjugated

RHOA 抗体  (AA 1-193) RHOA 抗体  (AA 1-193) RHOA 抗体 (AA 1-193) (ABIN559932)

RHOA 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1C1 unconjugated

RHOA 抗体  (AA 100-150) RHOA 抗体  (AA 100-150) RHOA 抗体 (AA 100-150) (ABIN351037)

RHOA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

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Popular Ras Homolog Gene Family, Member A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IF
Validations
  • (3)
  • (6)
Cat. No. ABIN559931
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), PLA
Validations
  • (6)
Cat. No. ABIN559932
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (6)
Cat. No. ABIN351037
Quantity 500 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN3020849
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (2)
  • (2)
Cat. No. ABIN758242
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (3)
Cat. No. ABIN7257513
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IHC (p), IF
Validations
  • (3)
Cat. No. ABIN790447
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP
Validations
  • (3)
Cat. No. ABIN6146932
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7269865
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7172843
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, PLA
Validations
  • (2)
Cat. No. ABIN513472
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7138096
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7127794
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN6266371
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (1)
Cat. No. ABIN3186754
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Ras Homolog Gene Family, Member A 抗体

Aktas, Un, Omer Barlas, Ozturk, Ilkay Karagul: "Evaluation of the Rho A/Rho-kinase pathway in the uterus of the rat model of polycystic ovary syndrome." in: Reproductive biology, (2019) (PubMed).

Stanley, Heo, Mauck, Mourkioti, Shore: "Elevated BMP and mechanical signaling through YAP1/RhoA Poises FOP Mesenchymal Progenitors for Osteogenesis." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, (2019) (PubMed).

Costa, Carina, Conigliaro, Raimondi, De Luca, Bellavia, Salamanna, Setti, Alessandro, Fini, Giavaresi: "miR-31-5p Is a LIPUS-Mechanosensitive MicroRNA that Targets HIF-1α Signaling and Cytoskeletal Proteins." in: International journal of molecular sciences, Vol. 20, Issue 7, (2019) (PubMed).

Gu, Feng, Yu, Yuan, Yin, Ding, Zhao, Xu, Xu, Che: "Fasudil attenuates soluble fms-like tyrosine kinase-1 (sFlt-1)-induced hypertension in pregnant mice through RhoA/ROCK pathway." in: Oncotarget, Vol. 8, Issue 61, pp. 104104-104112, (2017) (PubMed).

Zhang, He, Lu, Bian, Yang, Fu, Wu, Li: "HSF1 Relieves Amyloid-?-Induced Cardiomyocytes Apoptosis." in: Cell biochemistry and biophysics, (2015) (PubMed).

Jeong, Park, Kim, Kim, Ahn, Bae, Kim, Kim, Im, Lee, Kwon, Baek: "RhoA is associated with invasion and poor prognosis in colorectal cancer." in: International journal of oncology, Vol. 48, Issue 2, pp. 714-22, (2015) (PubMed).

Ma, Liu, Zhang, Geng, Li: "Relationship of RhoA signaling activity with ezrin expression and its significance in the prognosis for breast cancer patients." in: Chinese medical journal, Vol. 126, Issue 2, pp. 242-7, (2013) (PubMed).

Ellerbroek, Wennerberg, Burridge: "Serine phosphorylation negatively regulates RhoA in vivo." in: The Journal of biological chemistry, Vol. 278, Issue 21, pp. 19023-31, (2003) (PubMed).

Sawada, Itoh, Yamashita, Doi, Inoue, Masatsugu, Fukunaga, Sakaguchi, Sone, Yamahara, Yurugi, Nakao: "cGMP-dependent protein kinase phosphorylates and inactivates RhoA." in: Biochemical and biophysical research communications, Vol. 280, Issue 3, pp. 798-805, (2001) (PubMed).

Fagan, Oliveira, Pittler: "Sequence of rho small GTP-binding protein cDNAs from human retina and identification of novel 5' end cloning artifacts." in: Experimental eye research, Vol. 59, Issue 2, pp. 235-7, (1995) (PubMed).

Aliases for Ras Homolog Gene Family, Member A 抗体

ras homolog family member A (RHOA) 抗体
ras homolog family member A (Rhoa) 抗体
ras homolog family member A S homeolog (rhoa.S) 抗体
ras homolog family member A (rhoa) 抗体
ras homolog family member A L homeolog (rhoa.L) 抗体
ras homolog gene family, member Aa (rhoaa) 抗体
ras homolog family member Ca (rhoca) 抗体
ARH12 抗体
arh12 抗体
ARHA 抗体
Arha 抗体
arha 抗体
Arha1 抗体
Arha2 抗体
arha2 抗体
ARHC 抗体
RHO1 抗体
RHO12 抗体
rho12 抗体
rhoa 抗体
Rhoa 抗体
rhoae 抗体
RHOH12 抗体
rhoh12 抗体
wu:fa66g04 抗体
wu:fb26g07 抗体
xrhoa 抗体
zgc:64015 抗体
zgc:66058 抗体
zgc:85805 抗体
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