anti-RHOA (RHOA) 抗体产品概述

Full name:
anti-Ras Homolog Gene Family, Member A 抗体 (RHOA)
在www.antibodies-online.cn可供9 Ras Homolog Gene Family, Member A (RHOA) 抗体的2不同的供货商。 再加上,我们可以发RHOA 蛋白 (7)RHOA 试剂盒 (6)和数多这个蛋白质的别的产品。 总共22 RHOA产品已列进来了。
别名:
ARH12, Arha, Arha1, Arha2, RHO1, RHO12, Rhoa, RHOH12, wu:fa66g04, wu:fb26g07, xrhoa, zgc:66058, zgc:85805

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  1. Human Polyclonal RHOA Primary Antibody for IHC, ELISA - ABIN1994388 : Yeramian, Chardin, Madaule, Tavitian: Nucleotide sequence of human rho cDNA clone 12. in Nucleic acids research 1987 (PubMed)
    Show all 2 references for 1994388

更多抗RHOA的相互作用对抗体

Xenopus laevis Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. Mgc's GAP activity down-regulates the active populations of RhoA and Rac1 at localized regions of epithelial cells and is necessary for successful cytokinesis and cell-cell junction structure

  2. Data show that shortly after anaphase onset oocytes and embryonic cells exhibit cortical waves of Rho activity and F-actin polymerization.

  3. CASZ1 (显示 CASZ1 抗体)/Egfl7 (显示 EGFL7 抗体)/RhoA pathway is necessary for promoting endothelial cell behaviors associated with proper vascular assembly.

  4. RhoA can be considered a component of the intracellular pattern formation system.

  5. Kazrin (显示 KAZ 抗体) interacts with ARVCF (显示 ARVCF 抗体)-catenin, spectrin and p190B (显示 ARHGAP5 抗体) RhoGAP (显示 ARHGAP1 抗体), and modulates RhoA activity.

  6. Morphogenesis of the primitive gut tube is generated by Rho/ROCK/myosin II-mediated endoderm rearrangements.

Human Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. P311 could accelerate skin wound reepithelialization by promoting the migration of Epidermal Stem Cell through RhoA and Rac1 activation.

  2. Findings indicate a tumor suppressive role for G protein subunit alpha 13 (Galpha13 (显示 GNA13 抗体)) and rhoA GTP-binding protein (RhoA) in Burkitt's lymphoma and diffuse large B-cell lymphoma (DLBCL).

  3. RhoA/ROCK and Raf-1 (显示 RAF1 抗体)/CK2 (显示 CSNK2A1 抗体) pathway are responsible for TNF-alpha (显示 TNF 抗体)-mediated endothelial cytotoxicity via regulation of the vimentin (显示 VIM 抗体) cytoskeleton.

  4. Rac (显示 AKT1 抗体) is required to stimulate the remodeling of mast cells, triggering actin-mediated flattening of the cell periphery to create an active degranulation zone, whereas RhoA controls the streaming of highly motile granules into the active zone.

  5. the use of N1-Guanyl (显示 GUCA2A 抗体)-1,7-diaminoheptane, a DHPS (显示 DHPS 抗体) inhibitor, resulted in a significant decrease in tumor formation in vivo. In patients with esophageal squamous cell carcinoma (ESCC), overexpression of DHPS (显示 DHPS 抗体) in ESCC tumors was significantly associated with worse recurrence-free survival, and correlated with distant metastasis.

  6. Besides controlling cyclin (显示 PCNA 抗体)/CDK (显示 CDK4 抗体) kinase activity, p27 (显示 PAK2 抗体) also regulates cytoskeletal dynamics, cell motility and cell invasion. Following processing by caspases, p27 (显示 PAK2 抗体) fails to bind to RhoA and to inhibit its activation, and thereby abolishes the ability of p27 (显示 PAK2 抗体) to stimulate cell migration and invasion

  7. Higher proportions of early-onset Diffuse Gastric Cancers (DGCs) contained somatic mutations in CDH1 (显示 CDH1 抗体) or TGFBR1 (显示 TGFBR1 抗体) compared with late-onset DGCs. A smaller proportion of early-onset DGCs contained somatic mutations in RHOA. CDH1 (显示 CDH1 抗体) alterations, but not RHOA mutations, were associated with shorter survival times. Female predominance in early-onset DGC (显示 GGCX 抗体) may be related to relatively high rates of somatic CDH1 (显示 CDH1 抗体) and TGFBR1 (显示 TGFBR1 抗体) mutations.

  8. Data suggest that SmgGDS (显示 RAP1GDS1 抗体)-558 splice variant exhibits a fold containing tandem copies of armadillo (显示 PKP1 抗体)-repeat motifs not present in other guanine nucleotide exchange factors (GEFs); SmgGDS (显示 RAP1GDS1 抗体) harbors distinct positively and negatively charged regions, both of which play critical roles in binding to RhoA and in GEF (显示 SLC2A4RG 抗体) activity. (SmgGDS (显示 RAP1GDS1 抗体) = smg (显示 SNRPG 抗体) p21 (显示 CDKN1A 抗体) stimulatory GDP exchange protein; RhoA = ras homolog gene family, member A (显示 CXCL14 抗体))

  9. RhoA had a positive effect on ESC proliferation, and PKN1 (显示 PKN1 抗体) activity was up-regulated by the active RhoA mutant (G14V) and suppressed by RhoA T19N. The effect of RhoA on ESC proliferation is mediated by activation of the PKN1 (显示 PKN1 抗体)-cyclin D1 (显示 CCND1 抗体) pathway in vitro.

  10. RhoA works in concert with Fmn1 to control assembly of the specialized apical actin network in multiciliated epithelial cells.

Pig (Porcine) Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. Pseudorabies virus US3 expression led to RhoA phosphorylation at serine 188 to induce actin rearrangements.

  2. Data indicate that TNF-alpha (显示 TNF 抗体) stimulates Rac (显示 AKT1 抗体), ADAM17/TACE (显示 ADAM17 抗体), and RhoA through the guanine nucleotide exchange factor (显示 ARHGEF12 抗体) (GEF)-H1 (显示 ARHGEF2 抗体).

  3. Contractile pulmonary arterial myocytes exhibit marked Rho-dependent actin polymerization in hypoxia, with increased active RhoA and LIMK (显示 LIMK1 抗体) phosphorylation.

  4. Results suggest that Rac1 and RhoA are regulated by TGFbeta1 (显示 TGFB1 抗体) in the process of endothelial tube formation in collagen I gels.

  5. The concentration of RhoA mRNA and activated RhoA enzyme were greater in urothelium than in detrusor. Rho kinase (显示 ROCK1 抗体) inhibitor Y-27632 showed a stronger inhibitory effect in detrusor with intact urothelium.

  6. Thrombin (显示 F2 抗体) stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1 (显示 F2R 抗体), RhoA, and myocardin (显示 MYOCD 抗体).

Mouse (Murine) Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. P311 could accelerate skin wound reepithelialization by promoting the migration of Epidermal Stem Cell through RhoA and Rac1 activation.

  2. We show that RhoA mRNA levels were significantly higher compared with the RhoB mRNA levels in ESCs (显示 NR2E3 抗体) as well in various cancer cell lines and this difference could be accounted for by differences in the activities of the corresponding promoters.

  3. Results strongly support the hypothesis that spinal RhoA/ROCK signaling plays a central role in the neuropathic pain. In addition, simvastatin might exert its antihyperalgesic and antiallodynic effects through the attenuation of sensitization of spinal nociceptive transmission that is modulated by mechanisms dependent on the RhoA/ROCK signaling.

  4. Findings suggest that atorvastatin attenuates diabetes-associated renal injury by reducing reactive oxygen species (ROS (显示 ROS1 抗体)) generation, RhoA activity and normalizing Akt (显示 AKT1 抗体)/GSK3beta (显示 GSK3b 抗体) signaling pathways.

  5. findings describe a novel RhoA regulatory mechanism.

  6. ANXA1 (显示 ANXA1 抗体) restores Abeta42-induced blood brain barrier disruption through inhibition of RhoA-ROCK signaling pathway

  7. study delineates a mechanism in which NCAM (显示 NCAM1 抗体) promotes ephrin-A5 (显示 EFNA5 抗体)-dependent clustering of EphA3 (显示 EPHA3 抗体) through interaction of the NCAM (显示 NCAM1 抗体) Ig2 domain and the EphA3 (显示 EPHA3 抗体) CRD (显示 CRX 抗体), stimulating EphA3 (显示 EPHA3 抗体) autophosphorylation and RhoA signaling necessary for growth cone repulsion in GABAergic interneurons in vitro, which may extend to remodeling of axonal terminals of interneurons in vivo.

  8. M0 and M2 macrophages have a radically different phenotype and polarity from M1 macrophages, and that this is mirrored in dissonant response to RhoA pathway interference.

  9. the cross-talk between canonical and non-canonical signaling pathways of Wnt3A (显示 WNT3A 抗体), which induces GSK-3beta (显示 GSK3b 抗体) phosphorylation and beta-catenin (显示 CTNNB1 抗体) accumulation through RhoA and ROCK activation.

  10. these findings reveal that Arhgef1 functions as a negative regulator of neurite outgrowth through regulating RhoA-cofilin pathway and actin dynamics.

Cow (Bovine) Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. RhoA and membrane fluidity mediates the spatially polarized Src (显示 SRC 抗体)/FAK (显示 PTK2 抗体) activation in response to shear stress.

  2. the Lbc (显示 AKAP13 抗体)/alpha-catulin (显示 CTNNAL1 抗体) axis participates in 5-HT (显示 DDC 抗体)-induced PASMC mitogenesis and RhoA/ROCK signaling, and may be an interventional target in diseases involving vascular smooth muscle remodeling.

  3. The RhoA/ROCK signaling pathway is an important negative regulator of vascular calcification.

  4. Vascular endothelial-cadherin signals through RhoA and actin cytoskeletal and affects cell-matrix adhesion

  5. Thrombospondin has a role in inducing RhoA inactivation through FAK (显示 PTK2 抗体)-dependent signaling to stimulate focal adhesion disassembly

  6. KCl directly increased Rho and ROCK activities in a concentration-dependent fashion that paralleled closely the effect of KCl on lung smooth muscle tone and [Ca(2 (显示 CA2 抗体)+)](i), as well as the voltage-dependent Ca(2 (显示 CA2 抗体)+) currents

  7. the Rho-ROCK signal pathway contributes to VEGF-induced hyperpermeability. Myosin light-chain phosphorylation and actin stress fiber formation occur concomitantly with the increase in permeability upon VEGF stimulation.

  8. Formation of polygonal actin network in endothelial cells is a novel rhoA associated response to hypertonic stress.

  9. Cadherins, RhoA and Rac1, have important roles in mechanotransduction and that endothelial and smooth muscle cells use different mechanisms to respond to stretch.

  10. Results indicate that hypergravity induces ATP release and actin reorganization via RhoA activation and FAK (显示 PTK2 抗体) phosphorylation, thereby activating cell proliferation and migration in bovine aortic endothelial cells.

Zebrafish Ras Homolog Gene Family, Member A (RHOA) interaction partners

  1. Activating Rho could be beneficial to suppress Kras mutant-induced liver malignancies.

RHOA 抗原简介

Antigen Summary

Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA- DIAPH1 signaling pathway plays an important role in ERBB2- dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.

Alternative names and synonyms associated with RHOA

  • RSA-14-44 protein (RSA-14-44) 抗体
  • ras homolog family member A (RHOA) 抗体
  • ras homolog family member A (rhoa-b) 抗体
  • ras homolog family member A (rhoa) 抗体
  • ras homolog family member A (Rhoa) 抗体
  • ras homolog family member A (rhoa-a) 抗体
  • ras homolog gene family, member A (Rhoa) 抗体
  • ras homolog gene family, member A (RHOA) 抗体
  • ras homolog gene family, member Aa (rhoaa) 抗体
  • ARH12 抗体
  • Arha 抗体
  • Arha1 抗体
  • Arha2 抗体
  • RHO1 抗体
  • RHO12 抗体
  • Rhoa 抗体
  • RHOH12 抗体
  • wu:fa66g04 抗体
  • wu:fb26g07 抗体
  • xrhoa 抗体
  • zgc:66058 抗体
  • zgc:85805 抗体

Protein level used designations for RHOA

ras homolog gene family, member A , transforming protein RhoA , aplysia ras-related homolog A2 , Aplysia ras-related homolog 12 , h12 , oncogene RHO H12 , rho cDNA clone 12 , small GTP binding protein RhoA , plysia ras-related homolog A2 , rho1 GTP-binding protein , Rho A , Ras family member A , Rho family GTPase , aplysia ras-related homolog A , aplysia ras-related homolog A1 , ras homolog A1 , ras homolog A2 , ras homolog gene family, member A1 , ras homolog gene family, member A2 , gb , p21 , RhoA GTPase

GENE ID SPECIES
297173 Rattus norvegicus
100302078 Ovis aries
380133 Xenopus laevis
448080 Xenopus (Silurana) tropicalis
387 Homo sapiens
117273 Rattus norvegicus
403954 Canis lupus familiaris
379416 Xenopus laevis
396849 Sus scrofa
11848 Mus musculus
338049 Bos taurus
395442 Gallus gallus
406411 Danio rerio
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