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Human p38 ELISA Kit for Cell ELISA - ABIN1981835
Han, Lee, Bibbs, Ulevitch: A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. in Science (New York, N.Y.) 1994
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Human p38 ELISA Kit for Sandwich ELISA - ABIN625229
Brenner, Rosenhagen, Brandt, Schmitt, Jung, Schemmer, Schmidt, Mieth, Bruckner, Lichtenstern, Martin, Weigand, Hofer: Cell death biomarkers as early predictors for hepatic dysfunction in patients after orthotopic liver transplantation. in Transplantation 2012
S. aureus evades phagophores and prevents further degradation by a MAPK14/p38alpha (显示 MAPK14 ELISA试剂盒) MAP kinase (显示 MAPK1 ELISA试剂盒)-mediated blockade of autophagy.
p38 (显示 CRK ELISA试剂盒)-dependent mechanism that phosphorylates GATA-2 (显示 GATA2 ELISA试剂盒) and increases GATA-2 (显示 GATA2 ELISA试剂盒) target gene activation has been demonstrated. This mechanism establishes a growth-promoting chemokine (显示 CCL1 ELISA试剂盒)/cytokine circuit in acute myeloid leukemia (显示 BCL11A ELISA试剂盒) cells.
our results strongly indicate that the crosstalk between p38 (显示 CRK ELISA试剂盒) and Akt (显示 AKT1 ELISA试剂盒) pathways can determine special AT-rich sequence-binding protein 2 (显示 SATB2 ELISA试剂盒) expression and epithelial character of non-small-cell lung carcinoma cells
Osmotic stress promotes TEAD4 (显示 TEAD4 ELISA试剂盒) cytoplasmic translocation via p38 MAPK (显示 MAPK14 ELISA试剂盒) in a Hippo-independent manner. Stress-induced TEAD inhibition predominates YAP (显示 YAP1 ELISA试剂盒)-activating signals and selectively suppresses YAP (显示 YAP1 ELISA试剂盒)-driven cancer cell growth.
TGF-beta (显示 TGFB1 ELISA试剂盒) induces p38alpha (mitogen-activated protein kinase 14 (显示 MAPK14 ELISA试剂盒) [MAPK14 (显示 MAPK14 ELISA试剂盒)]), which in turn phosphorylates NR4A1 (显示 NR4A1 ELISA试剂盒), resulting in nuclear export of the receptor.
Data suggest that suppression of nonsense-mediated RNA decay due to persistent DNA damage (from exposure to either mutagens, gamma rays, or oxidative stress) requires the activity of p38alpha (显示 MAPK14 ELISA试剂盒) MAPK (显示 MAPK1 ELISA试剂盒) (MAPK14 (显示 MAPK14 ELISA试剂盒), mitogen-activated protein kinase 14 (显示 MAPK14 ELISA试剂盒), MAP kinase p38 alpha (显示 MAPK14 ELISA试剂盒)); mRNA of ATF3 (activating transcription factor 3 (显示 ATF3 ELISA试剂盒)) is stabilized by persistent DNA damage in a p38alpha (显示 MAPK14 ELISA试剂盒) MAPK (显示 MAPK1 ELISA试剂盒)-dependent manner.
VEGF (显示 VEGFA ELISA试剂盒)-activated p38alpha (显示 MAPK14 ELISA试剂盒) phosphorylates coronin 1B (显示 CORO1B ELISA试剂盒) at Ser2 (显示 JAG2 ELISA试剂盒) and activates the Arp2 (显示 ACTR2 ELISA试剂盒)/3 complex by liberating it from coronin 1B (显示 CORO1B ELISA试剂盒).
findings show that endothelial MAPKs ERK (显示 EPHB2 ELISA试剂盒), p38 (显示 CRK ELISA试剂盒), and JNK (显示 MAPK8 ELISA试剂盒) mediate diapedesis-related and diapedesis-unrelated functions of ICAM-1 (显示 ICAM1 ELISA试剂盒) in cerebral and dermal microvascular endothelial cells
Tetraarsenic hexoxide (As4O6) induced G2/M arrest, apoptosis and autophagic cell death through PI3K (显示 PIK3CA ELISA试剂盒)/Akt (显示 AKT1 ELISA试剂盒) and p38 MAPK (显示 MAPK14 ELISA试剂盒) pathways alteration in SW620 colon cancer cells.
The N-Terminal phosphorylation of RB by p38 (显示 CRK ELISA试剂盒) bypasses its inactivation by cyclin (显示 PCNA ELISA试剂盒)-dependent kinases and prevents proliferation in cancer cells.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.