Use your antibodies-online credentials, if available.
We found p-JNK2 up-regulation in AUC and its early down-regulation in UC-CRC (显示 CALR ELISA试剂盒) and CRC (显示 CALR ELISA试剂盒) carcinogenesis.
JNK2 was a novel direct target of miR (显示 MLXIP ELISA试剂盒)-20a-5p.
The release of infectious respiratory syncytial virus (RSV) virions from infected cells was significantly reduced by JNK1 (显示 MAPK8 ELISA试剂盒)/2 siRNA knockdown, implicating JNK1 (显示 MAPK8 ELISA试剂盒)/2 as a key host factor for RSV virus production.
PXR (显示 NR1I2 ELISA试剂盒) regulates the intestinal epithelial barrier during inflammation by modulating cytokine-induced MLCK (显示 MYLK ELISA试剂盒) expression and JNK1 (显示 MAPK8 ELISA试剂盒)/2 activation
Phloretin is able to inhibit NSCLC A549 cell growth by inducing apoptosis through P38 MAPK (显示 MAPK14 ELISA试剂盒) and JNK1 (显示 MAPK8 ELISA试剂盒)/2 pathways, and therefore may prove to be an adjuvant to the treatment of non-small cell lung cancer
In hepatocytes, JNK1 (显示 MAPK8 ELISA试剂盒) and JNK2 appear to have combined effects in protecting from drug-induced liver injury.
Inhibition of JNK1 (显示 MAPK8 ELISA试剂盒)/2 activity suppressed Hedgehog (显示 SHH ELISA试剂盒) pathway activity in acquired chemoresistant cancer cells.
although JNK (显示 MAPK8 ELISA试剂盒) activation and RIP3 (显示 RIPK3 ELISA试剂盒) expression are induced by FS, neither contributes to the liver injury.
These data suggest that JNK1 (显示 MAPK8 ELISA试剂盒)/2 may play an important role in promoting the replication of Penicillium marneffei.
Interleukin-1 acts via the JNK-2 signaling pathway to induce aggrecan (显示 ACAN ELISA试剂盒) degradation by human chondrocytes.
activation of JNK (显示 MAPK8 ELISA试剂盒) in the endoplasmic reticulum stress response precedes activation of XBP1 (显示 XBP1 ELISA试剂盒).
JNK-2 regulates aggrecan (显示 ACAN ELISA试剂盒) degradation in cultured murine cartilage and surgically induced osteoarthritis in vivo following mechanical destabilization of the knee joint.
activation of astrocyte MMP2 (显示 MMP2 ELISA试剂盒)/JNK1 (显示 MAPK8 ELISA试剂盒)/2 contributes to the pathogenesis of pain hypersensitivity in the complex regional pain syndrome model
JNK1 (显示 MAPK8 ELISA试剂盒)/2-dependent regulation of p66ShcS36 phosphorylation, is reported.
This study demonstrated that the disruption of JNK2 appears to have a greater impact on tolerance than the other isoforms in the tail-flick but not the hot-plate test.
although JNK (显示 MAPK8 ELISA试剂盒) activation and RIP3 (显示 MPRIP ELISA试剂盒) expression are induced by FS, neither contributes to the liver injury.
morphine activated JNK2 through an arrestin-independent Src- and PKC-dependent mechanism, whereas fentanyl activated JNK2 through a Src-GRK3/arrestin-2-dependent and PKC-independent mechanism.
studies herein support that JNK2 inhibits cell differentiation in normal and cancer-derived mammary cells
Presynaptic c-Jun N-terminal Kinase 2 regulates NMDA receptor-dependent glutamate (显示 GRIN1 ELISA试剂盒) release.
this study indicates that JNK2 is a physiological kinase responsible for eNOS (显示 NOS3 ELISA试剂盒)-Ser (显示 SIGLEC1 ELISA试剂盒)(116) phosphorylation and regulates NO production.
Data show that proinflammatory cytokines induction was ERK1/2 (显示 MAPK1/3 ELISA试剂盒) and JNK1 (显示 MAPK8 ELISA试剂盒)/2 dependent.
These data suggest that the p38 (显示 MAPK14 ELISA试剂盒) and JNK (显示 MAPK8 ELISA试剂盒) signaling pathways play pivotal roles in PRRSV replication and may regulate immune responses during virus infection.
MPK9 and MPK12 (显示 MAPK12 ELISA试剂盒) are positive regulators of salicylic acid signaling in Arabidopsis guard cells.
MPK9 and MPK12 (显示 MAPK12 ELISA试剂盒) are key regulators mediating both abscisic acid (ABA) and Methyl jasmonate (MeJA) signalling in guard cells.
Data suggest that MPK9 is autoactivated via phosphorylation independent of any upstream MAPK (显示 MAPK1 ELISA试剂盒) kinase signaling; autophosphorylation occurs at both threonine and tyrosine residues in Thr (显示 TRH ELISA试剂盒)-Asp (显示 ASIP ELISA试剂盒)-Tyr (显示 TYR ELISA试剂盒) motif and in C-terminal regulatory extension.
MPK9 and MPK12 (显示 MAPK12 ELISA试剂盒) function redundantly downstream of extracellular reactive oxygen production and intracellular accumulation, cytosolic alkalisation and Ca(2 (显示 CA2 ELISA试剂盒)+)cytosolic oscillation in yeast elcictor-induced stomatal closure
MPK9 and MPK12 (显示 MAPK12 ELISA试剂盒) act downstream of ROS (显示 ROS1 ELISA试剂盒) and cytosolic Ca2 (显示 CA2 ELISA试剂盒)+ and upstream of anion channels in the guard cell abscisic acid signaling cascade.
MAP kinases MPK9 and MPK12 (显示 MAPK12 ELISA试剂盒) are preferentially expressed in guard cells and positively regulate ROS (显示 ROS1 ELISA试剂盒)-mediated ABA signaling.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
mitogen-activated protein kinase 9
, Jun kinase
, MAP kinase 9
, MAPK 9
, c-Jun N-terminal kinase 2
, c-Jun kinase 2
, stress-activated protein kinase 1a
, stress-activated protein kinase JNK2
, JNK/SAPK alpha
, mitogen activated protein kinase 9
, protein kinase, mitogen-activated 9
, stress activated protein kinase alpha II
, janus kinase 2
, c-JUN amino-terminal kinase-2 alpha1