anti-牛 MAPK14 抗体 for Immunoprecipitation

Recommended MAPK14 Antibody (supplied by: Log in to see )

抗原
Mitogen-Activated Protein Kinase 14 (MAPK14) 抗体
  • AP22.98
  • AP22_98
  • ATMPK14
  • mitogen-activated protein kinase 14
  • 186F5S
  • BG:DS00797.3
  • CG7393
  • D-p38
  • D-p38 MAPK
  • D-p38b
  • Dm p38b
  • Dmel\\CG7393
  • Dmp38b
  • Dp38
  • Dp38b
  • ESTS:186F5S
  • Mpk34C
  • anon-sts23
  • dp38b
  • p38
  • p38 MAPK
  • p38 beta
  • p38B
  • p38Kb
  • p38beta
  • CSBP
  • CSBP1
  • CSBP2
  • CSPB1
  • EXIP
  • Mxi2
  • PRKM14
  • PRKM15
  • RK
  • SAPK2A
  • p38ALPHA
  • Crk1
  • Csbp1
  • p38-alpha
  • p38MAPK
  • p38a
  • p38alpha
  • SAPK2a
  • CRK1
  • Csbp2
  • Exip
  • Hog
  • Prkm14
  • Prkm15
  • Sapk2A
  • p38Hog
  • csbp
  • mapk14a
  • mxi2
  • sapk2
  • sapk2a
  • mitogen-activated protein kinase 14
  • CG7393 gene product from transcript CG7393-RA
  • mitogen activated protein kinase 14
  • MPK14
  • MAPK14
  • Mapk14
  • p38b
  • mapk14
抗原表位
AA 341-360
51
43
24
17
16
10
10
9
9
9
8
8
8
8
7
5
5
5
4
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
小鸡, 牛, 犬, 豚鼠, Hamster, 人, 猴, 小鼠, 猪, 兔, 大鼠, 绵羊
297
135
128
25
16
15
12
10
10
9
7
4
4
4
3
3
3
2
1
1
1
宿主

239
60
2
2
克隆类型
多克隆
标记
This MAPK14 antibody is un-conjugated
12
9
9
9
9
7
1
1
1
1
1
1
1
1
1
1
1
应用范围
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
276
125
74
55
38
37
13
9
9
7
6
2
2
1
1
Supplier
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产品编号 ABIN5551337
3,587.17 ¥
(含税, 含运费)
来自4A Biotech Co.,Ltd.(本地经销商)
获取报价
中国 北京 101111
No. 88 KeChuang 6th Street
Room 801-803
Beijing Economic Technological Development Area
4A Biotech Co.,Ltd.
Tel 400-7060-959
传真 +86 10 56315212-8813
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1911926 IP WB Rabbit IgG AA 300-360, C-Term Log in to see Polyclonal
1 ABIN1911924 IP WB Rabbit IgG AA 1-50 Log in to see Polyclonal
1 ABIN307668 IP ELISA WB Rabbit AA 347-360 Log in to see Polyclonal
1 ABIN1102944 IP IHC WB Rabbit Log in to see Polyclonal
1 ABIN302107 IP WB Rabbit AA 341-360 Log in to see Polyclonal

General

抗原 Mitogen-Activated Protein Kinase 14 (MAPK14) 抗体
抗原表位 AA 341-360
(51), (43), (24), (17), (16), (10), (10), (9), (9), (9), (8), (8), (8), (8), (7), (5), (5), (5), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 小鸡, 牛, 犬, 豚鼠, Hamster, 人, 猴, 小鼠, 猪, 兔, 大鼠, 绵羊
(297), (135), (128), (25), (16), (15), (12), (10), (10), (9), (7), (4), (4), (4), (3), (3), (3), (2), (1), (1), (1)
宿主
(239), (60), (2), (2)
克隆类型
多克隆
标记 This MAPK14 antibody is un-conjugated
(12), (9), (9), (9), (9), (7), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
应用范围 Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
(276), (125), (74), (55), (38), (37), (13), (9), (9), (7), (6), (2), (2), (1), (1)
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MAPK14抗体详情

MAPK14目标详情 使用细节 贮存及处理 图像
特异性 Detects ~43 kDa corresponding to the molecular mass of p38 on SDS-PAGE immunoblots.
纯化方法 Serum
免疫原 A 20 residue synthetic peptide based on the Human p38 (residues 341-360) with the Cysteine residue added and coupled to KLH
亚型 IgG

MAPK14目标详情

MAPK14抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 MAP Kinase p38 alpha / MAPK14 (MAPK14 Antibody 摘要)
背景 The MAPK (mitogen activated protein kinase) comprises a family of ubiquitous praline-directed, protein-serine/threonine kinases which signal transduction pathways that control intracellular events including acute responses to hormones and major developmental changes in organisms (1). This super family consists of stress activated protein kinases (SAPKs), extracellular signal-regulated kinases (ERKs), and p38 kinases, each of which forms a separate pathway (2). The kinase members that populate each pathway are sequentially activated by phosphorylation. Upon activation, p38 MAPK/SAPK2α translocates into the nucleus where it phosphorylates one or more nuclear substrates, effecting transcriptional changes and other cellular processes involved in cell growth, division, differentiation, inflammation, and death (3). Specifically p38 always acts as a pro-apoptotic factor with its activation leading to the release of cytochrome c from mitochondria and cleavage of caspase 3 and its downstream effector, PARP (4). p38 MAPK is activated by a variety of chemical stress inducers including hydrogen peroxide, heavy metals, anisomycin, sodium salicylate, LPS, and biological stress signals such as tumor necrosis factor, interleukin-1, ionizing and UV irradiation, hyperosmotic stress and chemotherapeutic drugs (5). As a result, p38 alpha has been widely validated as a target for inflammatory disease including rheumatoid arthritis, COPD and psoriasis (6) and has also been implicated in cancer, CNS and diabetes (7).Synonyms: CSBP, CSBP1, CSBP2, CSPB1, Cytokine suppressive anti-inflammatory drug-binding protein, MAX-interacting protein 2, MXI2, Mitogen-activated protein kinase 14, SAPK2A, p38 alpha
基因ID 1432
NCBI登录号 NP_001306
UniProt Q16539
研究领域 Kinases/Phosphatases
途径 MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling

使用细节

MAPK14抗体详情 MAPK14目标详情 贮存及处理 图像 回页首
应用备注 Western blot: A 1/5000 dilution of this antibody was sufficient for detection of p38 in 20 μgof HeLa cell lysate by ECL Immunoblot analysis. Immunoprecipitation: 1/250. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用

贮存及处理

MAPK14抗体详情 MAPK14目标详情 使用细节 图像 回页首
状态 Liquid
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.