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抗Human MAPK13 抗体:
抗Mouse (Murine) MAPK13 抗体:
抗Rat (Rattus) MAPK13 抗体:
Human Monoclonal MAPK13 Primary Antibody for IF, WB - ABIN968270
Jiang, Zhang, Chen, Zhou, Liu, Bian, Zhou, Chen: [Study on the needle biopsies of 100 prostatic adenocarcinoma]. in Zhonghua bing li xue za zhi Chinese journal of pathology 2002
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AtMKK6 (显示 MAP2K6 抗体)-AtMPK13 (显示 MAPK1/3 抗体) module positively regulates lateral root formation.[AtMPK13 (显示 MAPK1/3 抗体)]
The p38delta (显示 MAPK1/3 抗体) mitogen-activated protein kinase (显示 MAPK1 抗体) was identified as a novel regulator of NLRP3 (显示 NLRP3 抗体) inflammasome activation in primary human macrophages, and thus, represents a potential target for modulation of atherosclerotic inflammation.
p38delta (显示 MAPK1/3 抗体) expression was significantly higher in esophageal squamous cell carcinoma tissues compared with paired normal controls. No significant association was found for p38delta (显示 MAPK1/3 抗体) between its expression and other clinicopathological parameters. In Eca109 cells, p38delta (显示 MAPK1/3 抗体) can promote the cell growth and motility. p38delta (显示 MAPK1/3 抗体) overexpression promotes tumorigenesis in nude mice when p38delta (显示 MAPK1/3 抗体) was stably over-expressed and p38ga...
MAPK13 gene knockdown using siRNA reduced the aldehyde dehydrogenase high cell population and abrogated the tumor-initiating ability.
p38gamma (显示 MAPK12 抗体) and p38delta (显示 MAPK1/3 抗体) reprogram liver metabolism by modulating neutrophil infiltration and provide a potential target for NAFLD (显示 TSC2 抗体) therapy
MAPK13 (显示 MAPK1/3 抗体) undergoes a larger interlobe configurational rearrangement upon activation compared with MAPK14 (显示 MAPK14 抗体).
PKCdelta (显示 PKCd 抗体) activates a MEKK1 (显示 MAP3K1 抗体)/MEK3 (显示 MAP2K3 抗体)/p38delta (显示 MAPK1/3 抗体) MAPK (显示 MAPK1 抗体) cascade to increase p53 (显示 TP53 抗体) levels and p53 (显示 TP53 抗体) drives p21(Cip1 (显示 CDKN1A 抗体)) gene expression.
esophageal squamous cell carcinoma cell lines which are p38delta (显示 MAPK1/3 抗体)-negative grew more quickly than cell lines which express endogenous p38delta (显示 MAPK1/3 抗体).
DNA methylation (显示 HELLS 抗体) alterations are widespread in melanoma; epigenetic silencing of MAPK13 (显示 MAPK1/3 抗体) contributes to melanoma progression
Data indicate that p38delta (显示 MAPK1/3 抗体) mediates oncogene (显示 RAB1A 抗体)-induced senescence through a p53 (显示 TP53 抗体)- and p16(INK4A (显示 CDKN2A 抗体))-independent mechanism.
GSK3alpha, GSK3beta (显示 GSK3b 抗体), and MAPK13 (显示 MAPK1/3 抗体) were found to be the most active tau kinases, phosphorylating tau at all four epitopes.
Results reveal that p38delta (显示 MAPK1/3 抗体) contributes both cell-autonomous and paracrine effects during the course of skin tumor formation.
p38gamma (显示 MAPK12 抗体) and p38delta (显示 MAPK1/3 抗体) control heart growth by modulating mTOR (显示 FRAP1 抗体) pathway through DEPTOR (显示 DEPTOR 抗体) phosphorylation and subsequent degradation.
Together, our results establish that p38gamma (显示 MAPK12 抗体) and p38delta (显示 MAPK1/3 抗体) are central to colitis-associated colon cancer formation through regulation of hematopoietic cell response to injury, and validate p38gamma (显示 MAPK12 抗体) and p38kappa as potential targets for cancer therapy.
p38gamma (显示 MAPK12 抗体) and p38delta (显示 MAPK1/3 抗体) are crucial regulators of inflammatory joint destruction in collagen-induced arthritis.
p27 (显示 CDKN1B 抗体) inhibition of COX-2 (显示 COX2 抗体) expression was specifically due to phosphorylation of transcription factor cAMP response element binding (CREB (显示 CREB1 抗体)) phosphorylation mediated by p38beta (显示 MAPK11 抗体) and p38delta (显示 MAPK1/3 抗体).
Aberrant p38delta (显示 MAPK1/3 抗体)-PKD1 (显示 PKD1 抗体) signaling in neutrophils may underlie development of acute lung injury and life-threatening acute respiratory distress syndrome.
p38gamma (显示 MAPK12 抗体) and p38delta (显示 MAPK1/3 抗体) kinases regulate the Toll-like receptor 4 (TLR4 (显示 TLR4 抗体))-induced cytokine production by controlling ERK1/2 (显示 MAPK1/3 抗体) protein kinase (显示 CDK7 抗体) pathway activation
results indicate that p38gamma (显示 MAPK12 抗体) and p38delta (显示 MAPK1/3 抗体) have a role in the suppression of tumor development
This gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene.
MAP kinase 13
, MAPK 13
, MAP kinase p38 delta
, mitogen-activated protein kinase p38 delta
, stress-activated protein kinase 4
, SAPK/Erk/kinase 4
, mitogen activated protein kinase 13
, p38 delta MAP kinase
, mitogen-activated protein kinase 13