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MAP3K3 抗体

(Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))
This gene product is a 626-amino acid polypeptide that is 96.5% identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively\; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
MAP3K3 抗体  (AA 1-220) MAP3K3 抗体  (AA 1-220) MAP3K3 抗体 (AA 1-220) (ABIN7268652)

MAP3K3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

MAP3K3 抗体 MAP3K3 抗体 MAP3K3 抗体 (ABIN7258882)

MAP3K3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

MAP3K3 抗体  (N-Term) MAP3K3 抗体  (N-Term) MAP3K3 抗体 (N-Term) (ABIN3044008)

MAP3K3 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

MAP3K3 抗体 by 适用

Find MAP3K3 抗体 for a variety of species such as anti-Mouse MAP3K3, anti-Human MAP3K3, anti-Rat MAP3K3. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find MAP3K3 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

MAP3K3 抗体 by 抗体来源

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MAP3K3 抗体 by 抗原表位

Find MAP3K3 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

MAP3K3 抗体 by 克隆形成能力

Find available monoclonal or polyclonal MAP3K3 抗体. Click on a link to go to the corresponding products.

MAP3K3 抗体 by 克隆

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MAP3K3 抗体 by 标记

Find MAP3K3 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MAP3K3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (4)
Cat. No. ABIN7268652
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (3)
Cat. No. ABIN7258882
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN3044008
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, PLA
Validations
  • (2)
Cat. No. ABIN517853
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6258264
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7299350
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (1)
Cat. No. ABIN7187280
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN7074682
Quantity 100 μL
Datasheet Datasheet

Application WB, IHC (p)
Validations
  • (1)
Cat. No. ABIN7211414
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN517854
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN517852
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF
Validations
  • (1)
Cat. No. ABIN3185519
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7268651
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, FACS, IF (cc)
Validations
Cat. No. ABIN6944073
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, IHC (p)
Validations
Cat. No. ABIN6284877
Quantity 50 μL
Datasheet Datasheet

Latest Publications for our MAP3K3 抗体

Yang, Lai, Lai, Hsu, Kuo, Yu, Lin, Yang, Kuo, Wu, Chung: "Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways." in: Anticancer research, Vol. 30, Issue 6, pp. 2135-43, (2010) (PubMed).

Nakamura, Johnson: "PB1 domains of MEKK2 and MEKK3 interact with the MEK5 PB1 domain for activation of the ERK5 pathway." in: The Journal of biological chemistry, Vol. 278, Issue 39, pp. 36989-92, (2003) (PubMed).

Huang, Yang, Lin, Walker, Cheng, Liu, Su: "Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3." in: Nature immunology, Vol. 5, Issue 1, pp. 98-103, (2003) (PubMed).

Uhlik, Abell, Johnson, Sun, Cuevas, Lobel-Rice, Horne, DellAcqua, Johnson: "Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock." in: Nature cell biology, Vol. 5, Issue 12, pp. 1104-10, (2003) (PubMed).

Ellinger-Ziegelbauer, Brown, Kelly, Siebenlist et al.: "Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 ..." in: The Journal of biological chemistry, Vol. 272, Issue 5, pp. 2668-74, (1997) (PubMed).

Aliases for MAP3K3 抗体

mitogen activated protein kinase kinase kinase 3 (Map3k3) 抗体
mitogen-activated protein kinase kinase kinase 3 (MAP3K3) 抗体
mitogen-activated protein kinase kinase kinase 3 (Map3k3) 抗体
mitogen-activated protein kinase kinase kinase 3 (map3k3) 抗体
AW548911 抗体
MAPKKK3 抗体
MEKK3 抗体
Mekk3 抗体
mKIAA4031 抗体
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