MAP3K2 (MAP3K2) ELISA试剂盒产品概述

Full name:
Mitogen-Activated Protein Kinase Kinase Kinase 2 ELISA试剂盒 (MAP3K2)
在www.antibodies-online.cn可供0 Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) ELISA试剂盒的不同的供货商。 再加上,我们可以发MAP3K2 抗体 (55)MAP3K2 蛋白 (7)和数多这个蛋白质的别的产品。 总共68 MAP3K2产品已列进来了。
别名:
9630061B06Rik, AI585793, MEKK2, Mekk2b
list all ELISA KIts 基因 基因ID UniProt
大鼠 MAP3K2 MAP3K2 171492  
 MAP3K2 MAP3K2 10746 Q9Y2U5
小鼠 MAP3K2 MAP3K2 26405  

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适于 MAP3K2 相互作用对的更多 ELISA 试剂盒

Human Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) interaction partners

  1. miR (显示 MLXIP ELISA试剂盒)-34c-3p may regulate triple-negative breast cancer progression by directly targeting the 3'-untranslated region of mitogen-activated protein kinase kinase kinase 2 (MAP3K2).

  2. Study found miR (显示 MLXIP ELISA试剂盒)-186 expression significantly decreased in lung cancer tissues and cells and MAP3K2 expression increased in the same cancer tissues. Also, results confirmed that MAP3K2 is a target gene of miR (显示 MLXIP ELISA试剂盒)-186 and both expression correlated with prognosis.

  3. SMYD3 (显示 SMYD3 ELISA试剂盒)-mediated methylation of MAP3K2 increases mutant K-Ras (显示 HRAS ELISA试剂盒)-induced activation of ERK1/2 (显示 MAPK1/3 ELISA试剂盒). (Review)

  4. Restoration of miR17/20a in solid tumor cells enhances the natural killer cell antitumor activity by targeting Mekk2

  5. HBXIP (显示 HBXIP ELISA试剂盒) activated ERK1/2 (显示 MAPK1/3 ELISA试剂盒) through up-regulating MEKK2.

  6. MEKK2 has a novel function as a regulator of ubiquitylation-dependent paxillin (显示 PXN ELISA试剂盒) redistribution in breast tumour cells.

  7. EBV microRNA BART (显示 BSND ELISA试剂盒) 18-5p targets MAP3K2 to facilitate persistence in vivo by inhibiting viral replication in B cells.

  8. Inhibitors of apoptosis proteins regulate myogenic differentiation by directly suppressing MEKK2/3-MEK5 (显示 MAP2K5 ELISA试剂盒)-ERK5 (显示 MAPK7 ELISA试剂盒) signaling.

  9. methylation of MAP3K2 by SMYD3 increases MAP kinase signalling and promotes the formation of Ras-driven carcinomas

  10. results strongly support a role for MEKK2 as a regulator of signaling that modulates breast tumor cell spread area and migration through control of focal adhesion stability

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) interaction partners

  1. FGF2 (显示 FGF2 ELISA试剂盒)/MEKK2 pathway mediates an alternative nonclassical pathway for beta-catenin (显示 CTNNB1 ELISA试剂盒) activation, and this pathway is a key regulator of bone formation by osteoblasts

  2. Stk38 (显示 STK38 ELISA试剂盒) protein kinase (显示 CDK7 ELISA试剂盒) has a role in inhibiting TLR9 (显示 TLR9 ELISA试剂盒)-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages

  3. methylation of MAP3K2 by SMYD3 increases MAP kinase signalling and promotes the formation of Ras-driven carcinomas

  4. MEKK2 is regulated through a phosphorylation-dependent association with 14-3-3 (显示 YWHAQ ELISA试剂盒), a group of adapters that modulate dimerization and association between proteins

  5. MEKK2 signaling contributes to right ventricular hypertrophy and altered myocardial inflammatory gene expression in response to hypoxia-induced pulmonary hypertension.

  6. MEKK2 alone can suppress T-cell TGF-beta (显示 TGFB1 ELISA试剂盒) responses. MEKK2 or MEKK3 (显示 MAP3K3 ELISA试剂盒) can cause ERK1/2 (显示 MAPK1/3 ELISA试剂盒) to phosphorylate SMAD2 (显示 SMAD2 ELISA试剂盒)/3 and suppress R-SMAD (显示 SMAD1 ELISA试剂盒)-dependent transcription. MEKK2 and MEKK3 (显示 MAP3K3 ELISA试剂盒) play overlapping roles in regulating Th-cell differentiation via TGF-beta (显示 TGFB1 ELISA试剂盒)

  7. Data show that HDAC4 (显示 HDAC5 ELISA试剂盒) binds and promotes the deacetylation and activation of a key MAP3 kinase, MEKK2.

  8. Data from experiments with Mekk2(-/-) mice show that MEKK2 may be required for controlling the strength of T cell receptor/CD3 (显示 CD3E ELISA试剂盒) signaling.

  9. PB1 domain mediates the association of MEKK2 and MEKK3 (显示 MAP3K3 ELISA试剂盒) with MEK5 (显示 MAP2K5 ELISA试剂盒) and that the respective PB1 domains of these kinases are critical for regulation of the ERK5 (显示 MAPK7 ELISA试剂盒) pathway.

  10. Rap1 (显示 TERF2IP ELISA试剂盒) and MEKK2 are critical upstream signaling molecules mediating BDNF (显示 BDNF ELISA试剂盒) stimulation of ERK5 (显示 MAPK7 ELISA试剂盒) in central nervous system neurons

MAP3K2 抗原简介

Antigen Summary

The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

Alternative names and synonyms associated with MAP3K2

  • mitogen activated protein kinase kinase kinase 2 (Map3k2) Elisa Kit
  • mitogen-activated protein kinase kinase kinase 2 (MAP3K2) Elisa Kit
  • mitogen-activated protein kinase kinase kinase 2 (Map3k2) Elisa Kit
  • 9630061B06Rik Elisa Kit
  • AI585793 Elisa Kit
  • MEKK2 Elisa Kit
  • Mekk2b Elisa Kit

Protein level used designations for MAP3K2

mitogen-activated protein kinase kinase kinase 2 , MAP/ERK kinase kinase 2 , MAPK/ERK kinase kinase 2 , MEK kinase 2 , MEKK 2 , mitogen activated protein kinase kinase kinase 2 , protein kinase MEKK2b

GENE ID SPECIES
171492 Rattus norvegicus
10746 Homo sapiens
26405 Mus musculus
612902 Canis lupus familiaris
100050628 Equus caballus
504592 Bos taurus
424225 Gallus gallus
100621234 Sus scrofa
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