anti-MAP3K12 (MAP3K12) 抗体产品概述

在www.antibodies-online.cn可供59 Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12) 抗体的13不同的供货商。 再加上,我们可以发MAP3K12 蛋白 (7)和数多这个蛋白质的别的产品。 总共71 MAP3K12产品已列进来了。
别名:
Delta1, DKFZp459K2433, DLK, DLK-1, FA1, map3k12, map3k12a, MEKK12, MGC151798, MUK, pG2, PK, Pref-1, PREF1, zgc:77370, ZOG, ZPK, ZPKP1
列出全部抗体 基因 基因ID UniProt
MAP3K12 8788 P80370
MAP3K12 25579 Q63796
MAP3K12 26404 Q60700

最受欢迎的抗anti-MAP3K12 (MAP3K12) 抗体

抗Human MAP3K12 抗体:

抗Rat (Rattus) MAP3K12 抗体:

抗Mouse (Murine) MAP3K12 抗体:

所有可销售的anti-MAP3K12 抗体

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更多抗MAP3K12的相互作用对抗体

Human Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12) interaction partners

  1. results demonstrate that miR (显示 MLXIP 抗体)-129-5p inhibits non-small cell lung cancer stemness and chemoresistance through direct targeting of DLK1 (显示 DLK1 抗体)

  2. A complex defect of DLK1 (显示 DLK1 抗体) ( approximately 14-kb deletion and 269-bp duplication) was identified in a family with central precocious puberty. This deletion included the 5' untranslated region and the first exon of DLK1 (显示 DLK1 抗体), including the translational start site. Only family members who inherited the defect from their father have precocious puberty, consistent with the known imprinting of DLK1 (显示 DLK1 抗体).

  3. Loss of DLK1 (显示 DLK1 抗体) expression is associated with fetal growth retardation complications of pregnancy.

  4. LZK (显示 MAP3K13 抗体) cooperates with DLK (显示 DAPK3 抗体) to promote retinal ganglion cell death in response to axon injury.

  5. In neonatal skin, DLK1 (显示 DLK1 抗体) exhibited a high degree of monoallelic expression from the paternal allele.

  6. The study evaluated the roles of extracellular soluble DLK1 (显示 DLK1 抗体), comprising six EGF (显示 EGF 抗体)-like domains and juxtamembrane regions, in human pancreatic cancer MIA (显示 MIA 抗体) PaCa-2 cells in vitro and in vivo. Soluble DLK1 (显示 DLK1 抗体) exerted antitumor effects not only in cancer cell migration and anchorage-independent cell growth but also in in vivo tumor growth.

  7. Treatment of mice with recombinant human DLK1 (显示 DLK1 抗体) during pregnancy has significant effects on AT of the offspring. This can be associated with counter-regulatory changes in the Notch1 (显示 NOTCH1 抗体) signaling cascade.

  8. NOTCH1 (显示 NOTCH1 抗体) ligand Delta-like 1 (显示 DLL1 抗体) homolog (DLK1 (显示 DLK1 抗体)) self interacts

  9. Pref-1 (显示 DLK1 抗体) induces insulin (显示 INS 抗体) synthesis and secretion via two independent pathways

  10. REVIEW: Regulation of Beta-Cell Function and Mass by the Dual Leucine Zipper Kinase

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12) interaction partners

  1. Results provide the first evidence that axon guidance genes are downstream targets of the dual leucine zipper kinase (DLK) signaling pathway, which through their regulation probably modulates neuronal cell development, structure and function.

  2. LZK (显示 MAP3K13 抗体) cooperates with DLK (显示 DAPK3 抗体) to promote retinal ganglion cell death in response to axon injury.

  3. the prevention of the nuclear localization of DLK (显示 DAPK3 抗体) as induced by prediabetic signals with consecutive suppression of beta-cell apoptosis might constitute a novel target in the therapy of diabetes mellitus

  4. Data assesses DLK's role in axons of adult, injured CNS neurons in vivo and shows that DLK (显示 DAPK3 抗体) does not appear to have a critical function in axonal degeneration; function appears restricted to soma

  5. This study provides compelling evidence for the pivotal roles of the ZPK/DLK and MKK4/MAP2K4 (显示 MAP2K4 抗体)-dependent mechanism in axotomy-induced motoneuron death in neonates

  6. DLK (显示 DAPK3 抗体)-inducible knockouts displayed a modest increase in basal synaptic transmission but had an attenuation of the JNK/c-Jun stress response pathway activation and significantly reduced neuronal degeneration after kainic acid-induced seizures.

  7. Abundance of DLK (显示 DAPK3 抗体) in turn controlled the levels of downstream JNK (显示 MAPK8 抗体) signaling and apoptosis.

  8. DLK (显示 DAPK3 抗体) is required for RGC JNK (显示 MAPK8 抗体) activation and cell death in a rodent model of optic neuropathy

  9. The cell intrinsic factors that determine whether a neuron regenerates or undergoes apoptosis in response to axonal injury are not well defined. DLK (显示 DAPK3 抗体) is an essential upstream mediator of both of these divergent outcomes in the same cell type.

  10. These data demonstrate that DLK (显示 DAPK3 抗体) enhances regeneration by promoting a retrograde injury signal that is required for the activation of the neuronal proregenerative program.

MAP3K12 抗原简介

Antigen Summary

This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.

Alternative names and synonyms associated with MAP3K12

  • mitogen-activated protein kinase kinase kinase 12 (map3k12) 抗体
  • mitogen-activated protein kinase kinase kinase 12 (MAP3K12) 抗体
  • mitogen-activated protein kinase kinase kinase 12 (map3k12-a) 抗体
  • delta-like 1 homolog (Drosophila) (DLK1) 抗体
  • mitogen activated protein kinase kinase kinase 12 (Map3k12) 抗体
  • mitogen-activated protein kinase kinase kinase 12 (Map3k12) 抗体
  • Delta1 抗体
  • DKFZp459K2433 抗体
  • DLK 抗体
  • DLK-1 抗体
  • FA1 抗体
  • map3k12 抗体
  • map3k12a 抗体
  • MEKK12 抗体
  • MGC151798 抗体
  • MUK 抗体
  • pG2 抗体
  • PK 抗体
  • Pref-1 抗体
  • PREF1 抗体
  • zgc:77370 抗体
  • ZOG 抗体
  • ZPK 抗体
  • ZPKP1 抗体

Protein level used designations for MAP3K12

mitogen-activated protein kinase kinase kinase 12 , mitogen activated protein kinase kinase kinase 12 type A , fetal antigen 1 , preadipocyte factor 1 , protein delta homolog 1 , secredeltin , MAPK-upstream kinase , Mitogen activated protein kinase 12 (Zipper (leucine) protein kinase) , Zipper (leucine) protein kinase , dual leucine zipper bearing kinase , dual leucine zipper kinase , leucine-zipper protein kinase , mixed lineage kinase , dual leucine zipper kinase DLK , leucine zipper protein kinase , protein kinase MUK , mitogen activated protein kinase kinase kinase 12 , zipper (leucine) protein kinase

GENE ID SPECIES
404626 Danio rerio
451940 Pan troglodytes
505427 Bos taurus
607170 Canis lupus familiaris
703059 Macaca mulatta
100064002 Equus caballus
100113430 Xenopus laevis
100172208 Pongo abelii
100358158 Oryctolagus cuniculus
100408788 Callithrix jacchus
100469942 Ailuropoda melanoleuca
100517714 Sus scrofa
8788 Homo sapiens
25579 Rattus norvegicus
7786 Homo sapiens
26404 Mus musculus
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